Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Z6BY
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Former ID |
DNC006980
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Drug Name |
JWH-243
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Synonyms |
JWH-243; CHEMBL220413; BDBM50192609
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C27H27NO2
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Canonical SMILES |
CCCCCN1C=C(C=C1C2=CC=C(C=C2)OC)C(=O)C3=CC=CC4=CC=CC=C43
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InChI |
1S/C27H27NO2/c1-3-4-7-17-28-19-22(18-26(28)21-13-15-23(30-2)16-14-21)27(29)25-12-8-10-20-9-5-6-11-24(20)25/h5-6,8-16,18-19H,3-4,7,17H2,1-2H3
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InChIKey |
IQIAZANEJACDNJ-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Cannabinoid receptor 1 (CB1) | Target Info | Inhibitor | [1] |
Cannabinoid receptor 2 (CB2) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Rap1 signaling pathway | ||||
Retrograde endocannabinoid signaling | ||||
Panther Pathway | Endogenous cannabinoid signaling | |||
Pathway Interaction Database | N-cadherin signaling events | |||
Reactome | Class A/1 (Rhodopsin-like receptors) | |||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Small Ligand GPCRs | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
BDNF signaling pathway | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB1 and CB2 receptors. Bioorg Med Chem Lett. 2006 Oct 15;16(20):5432-5. |
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