Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0ZY8H
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| Former ID |
DNC011414
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| Drug Name |
HI-280
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| Synonyms |
HI-280; CHEMBL40642; DDE280; AC1LAQRF; SCHEMBL14560609; CTK7B5926; BDBM50078253; 3-(Methylethyl)-6-(methylthiomethylthio)-4-benzylhydropyridin-2-one; 4-benzyl-6-(methylsulfanylmethylsulfanyl)-3-propan-2-yl-1H-pyridin-2-one; 4-benzyl-3-isopropyl-6-(methylsulfanylmethylsulfanyl)-1H-pyridin-2-one; 4-Benzyl-3-isopropyl-6-methylsulfanylmethylsulfanyl-1H-pyridin-2-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H21NOS2
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| Canonical SMILES |
CC(C)C1=C(C=C(NC1=O)SCSC)CC2=CC=CC=C2
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| InChI |
1S/C17H21NOS2/c1-12(2)16-14(9-13-7-5-4-6-8-13)10-15(18-17(16)19)21-11-20-3/h4-8,10,12H,9,11H2,1-3H3,(H,18,19)
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| InChIKey |
CCFCAWLPLYLQBS-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human immunodeficiency virus Reverse transcriptase (HIV RT) | Target Info | Inhibitor | [1] |
| References | Top | |||
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| REF 1 | Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistan... Bioorg Med Chem Lett. 1999 Jun 7;9(11):1593-8. | |||
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