Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D12THW
|
|||
| Drug Name |
AGN-241751
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Major depressive disorder [ICD-11: 6A70.3; ICD-10: F32.2; ICD-9: 296.2, 296.3] | Phase 2 | [1] | |
| Company |
Allergan
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | N-methyl-D-aspartate receptor (NMDAR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT03586427) AGN-241751 in the Treatment of Major Depressive Disorder. U.S. National Institutes of Health. | |||
| REF 2 | Positive modulation of NMDA receptors by AGN-241751 exerts rapid antidepressant-like effects via excitatory neurons. Neuropsychopharmacology. 2021 Mar;46(4):799-808. | |||
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