Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D7K0GP
|
|||
| Drug Name |
PT630
|
|||
| Drug Type |
Peptide
|
|||
| Indication | Colon cancer [ICD-11: 2B90.Z] | Preclinical | [1] | |
| Lung cancer [ICD-11: 2C25.0; ICD-9: 162] | Preclinical | [1] | ||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dipeptidyl peptidase 4 (DPP-4) | Target Info | Inhibitor | [1] |
| Prolyl endopeptidase FAP (FAP) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Protein digestion and absorption | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| TGF_beta_Receptor Signaling Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice. J Clin Invest. 2009 Dec;119(12):3613-25. | |||
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