Drug Information
Drug General Information | Top | |||
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Drug ID |
D92KUQ
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Drug Name |
ARN-6039
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Synonyms |
6-methoxy-5-morpholino-2-((3-(trifluoromethyl)pyridin-2-yl)methyl)-2,3-dihydro-1H-inden-1-one; 1675206-11-7; SCHEMBL16552820; COc1cc2C(=O)C(Cc3ncccc3C(F)(F)F)Cc2cc1N1CCOCC1
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Drug Type |
Small molecular drug
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Indication | Multiple sclerosis [ICD-11: 8A40] | Phase 1 | [1] | |
Company |
Arrien Pharmaceuticals; Boston Pharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C21H21F3N2O3
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Canonical SMILES |
COC1=C(C=C2CC(C(=O)C2=C1)CC3=C(C=CC=N3)C(F)(F)F)N4CCOCC4
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InChI |
1S/C21H21F3N2O3/c1-28-19-12-15-13(11-18(19)26-5-7-29-8-6-26)9-14(20(15)27)10-17-16(21(22,23)24)3-2-4-25-17/h2-4,11-12,14H,5-10H2,1H3
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InChIKey |
CQSDLVKTQRLMJB-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Nuclear receptor ROR-gamma (RORG) | Target Info | Agonist | [2] |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT03237832) A Phase 1 Study of ARN-6039 (ARN-6039). U.S. National Institutes of Health. | |||
REF 2 | Clinical pipeline report, company report or official report of Arrien Pharmaceuticals. |
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