Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DA85NC
|
|||
| Drug Name |
60P002
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Dengue [ICD-11: 1D20-1D2Z; ICD-10: A90, R50] | Phase 2 | [1] | |
| Company |
60 Degrees Pharmaceuticals
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Platelet-activating factor receptor (PTAFR) | Target Info | Antagonist | [2] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Staphylococcus aureus infection | ||||
| NetPath Pathway | IL5 Signaling Pathway | |||
| Leptin Signaling Pathway | ||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (q) signalling events | ||||
| Interferon gamma signaling | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Small Ligand GPCRs | ||||
| Interferon gamma signaling | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT02569827) Celgosivir or Modipafant as Treatment for Adult Participants With Uncomplicated Dengue Fever in Singapore. U.S. National Institutes of Health. | |||
| REF 2 | Clinical pipeline report, company report or official report of 60 Degrees Pharmaceuticals. | |||
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