Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
DI54FM
|
|||
Drug Name |
SAGE-718
|
|||
Drug Type |
Small molecule
|
|||
Indication | Alzheimer disease [ICD-11: 8A20; ICD-10: G30, G30.9; ICD-9: 331] | Phase 2 | [1] | |
Company |
Sage Therapeutics
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | N-methyl-D-aspartate receptor (NMDAR) | Target Info | Modulator | [2] |
References | Top | |||
---|---|---|---|---|
REF 1 | ClinicalTrials.gov (NCT04602624) An Open-Label Evaluation of the Safety and Tolerability of SAGE-718 in Participants With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease. U.S.National Institutes of Health. | |||
REF 2 | SAGE-718: A First-in-Class N-Methyl-d-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive Impairment. J Med Chem. 2022 Jul 14;65(13):9063-9075. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.