Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DMU9P2
|
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| Drug Name |
Efanesoctocog alfa
|
|||
| Synonyms |
BIVV001; Altuviiio
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|
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| Drug Type |
Protein
|
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| Indication | Haemophilia A [ICD-11: 3B10.0; ICD-9: 286] | Approved | [1] | |
| Company |
Sanofi
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Coagulation factor VIII (F8) | Target Info | Replacement | [2] |
| KEGG Pathway | Complement and coagulation cascades | |||
| Panther Pathway | Blood coagulation | |||
| Pathwhiz Pathway | Coagulation | |||
| Reactome | Platelet degranulation | |||
| Intrinsic Pathway of Fibrin Clot Formation | ||||
| Common Pathway of Fibrin Clot Formation | ||||
| COPII (Coat Protein 2) Mediated Vesicle Transport | ||||
| Cargo concentration in the ER | ||||
| WikiPathways | Complement and Coagulation Cascades | |||
| Blood Clotting Cascade | ||||
| Formation of Fibrin Clot (Clotting Cascade) | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of Sanofi | |||
| REF 2 | Efanesoctocog alfa for hemophilia A: results from a phase 1 repeat-dose study. Blood Adv. 2022 Feb 22;6(4):1089-1094. | |||
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