Drug Information
Drug General Information | Top | |||
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Drug ID |
DU10JI
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Drug Name |
CTP-543
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Synonyms |
Deuruxolitinib; D8-ruxolitinib; UNII-0CA0VSF91Y; Deuruxolitinib (USAN); Deuruxolitinib [USAN]; C-21543; (3R)-3-(2,2,3,3,4,4,5,5-octadeuteriocyclopentyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile; 1513883-39-0; CTP543; CHEMBL4594381; SCHEMBL19555526; GTPL11410; WHO 11622; D11866; (3R)-3-(2,2,3,3,4,4,5,5-D8)cyclopentyl-3-(4-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)-1Hpyrazol-1-yl)propanenitrile; H-Pyrazole-1-propanenitrile, beta-(cyclopentyl-2,2,3,3,4,4,5,5-d8)-4-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)-, (betaR)-
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Drug Type |
Small molecular drug
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Indication | Alopecia [ICD-11: ED70; ICD-9: 704.09] | Phase 2 | [1] | |
Company |
Concert Pharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C17H18N6
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Canonical SMILES |
C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
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InChI |
1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1/i1D2,2D2,3D2,4D2
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InChIKey |
HFNKQEVNSGCOJV-FBXGHSCESA-N
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CAS Number |
CAS 1513883-39-0
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PubChem Compound ID |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT03898479) Extension Study to Evaluate Safety and Efficacy of CTP-543 in Adults With Alopecia Areata. U.S. National Institutes of Health. | |||
REF 2 | Clinical pipeline report, company report or official report of Concert Pharmaceuticals. |
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