Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DUBW95
|
|||
| Drug Name |
Omburtamab
|
|||
| Drug Type |
Antibody
|
|||
| Indication | Neuroblastoma [ICD-11: 2D11.2; ICD-9: 194] | Phase 2/3 | [1] | |
| Company |
Y-mAbs Therapeutics
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | B7 homolog 3 (CD276) | Target Info | Inhibitor | [2] |
| KEGG Pathway | Cell adhesion molecules (CAMs) | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT03275402) 131I-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous System/Leptomeningeal Metastases. U.S. National Institutes of Health. | |||
| REF 2 | Mast cell proliferation in the cerebrospinal fluid after intraventricular administration of anti-B7H3 immunotherapy. Cancer Immunol Immunother. 2021 Feb 3. | |||
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