Drug Information
| Drug General Information | Top | |||
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| Drug ID |
DUM25X
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| Drug Name |
BMS-986120
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| Synonyms |
1478712-37-6; UNII-WDT28B7071; WDT28B7071; 4-(4-(((6-methoxy-2-(2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl)benzofuran-4-yl)oxy)methyl)-5-methylthiazol-2-yl)morpholine; 4-[4-[[6-methoxy-2-(2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-1-benzofuran-4-yl]oxymethyl]-5-methyl-1,3-thiazol-2-yl]morpholine; 4-(4-(((6-Methoxy-2-(2-methoxyimidazo(2,1-b)(1,3,4)thiadiazol-6-yl)benzofuran-4-yl)oxy)methyl)-5-methylthiazol-2-yl)morpholine; CHEMBL3716726; SCHEMBL15348871; GTPL10269; BDBM176061; EX-A3977; BMS986120; HY-19837; CS-0016978; US9688695, 94; 2-methoxy-6-[6-methoxy-4-[[5-methyl-2-(4-morpholinyl)-4-thiazolyl]methoxy]-2-benzofuranyl]-imidazo[2,1-b]-1,3,4-thiadiazole; Imidazo(2,1-b)-1,3,4-thiadiazole, 2-methoxy-6-(6-methoxy-4-((5-methyl-2-(4-morpholinyl)-4-thiazolyl)methoxy)-2-benzofuranyl)
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| Drug Type |
Small molecular drug
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| Indication | Thrombosis [ICD-11: DB61-GB90] | Phase 1 | [1] | |
| Company |
Bristol-Myers Squibb
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| Structure |
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Download2D MOL |
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| Formula |
C23H23N5O5S2
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| Canonical SMILES |
CC1=C(N=C(S1)N2CCOCC2)COC3=CC(=CC4=C3C=C(O4)C5=CN6C(=N5)SC(=N6)OC)OC
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| InChI |
1S/C23H23N5O5S2/c1-13-17(25-21(34-13)27-4-6-31-7-5-27)12-32-18-8-14(29-2)9-19-15(18)10-20(33-19)16-11-28-22(24-16)35-23(26-28)30-3/h8-11H,4-7,12H2,1-3H3
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| InChIKey |
MINMDCMSHDBHKG-UHFFFAOYSA-N
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| CAS Number |
CAS 1478712-37-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostate apoptosis response-4 (PAWR) | Target Info | Antagonist | [2] |
| References | Top | |||
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| REF 1 | ClinicalTrials.gov (NCT02439190) CV004-007 Thrombosis Chamber Study. U.S. National Institutes of Health. | |||
| REF 2 | PAR4 (Protease-Activated Receptor 4) Antagonism With BMS-986120 Inhibits Human Ex Vivo Thrombus Formation. Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):448-456. | |||
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