Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
DW7PT6
|
|||
Drug Name |
SPK-8011
|
|||
Drug Type |
Gene therapy
|
|||
Indication | Haemophilia A [ICD-11: 3B10.0; ICD-9: 286] | Phase 1/2 | [1] | |
Company |
Spark Therapeutics
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Coagulation factor VIII (F8) | Target Info | Replacement | [1] |
KEGG Pathway | Complement and coagulation cascades | |||
Panther Pathway | Blood coagulation | |||
Pathwhiz Pathway | Coagulation | |||
Reactome | Platelet degranulation | |||
Intrinsic Pathway of Fibrin Clot Formation | ||||
Common Pathway of Fibrin Clot Formation | ||||
COPII (Coat Protein 2) Mediated Vesicle Transport | ||||
Cargo concentration in the ER | ||||
WikiPathways | Complement and Coagulation Cascades | |||
Blood Clotting Cascade | ||||
Formation of Fibrin Clot (Clotting Cascade) |
References | Top | |||
---|---|---|---|---|
REF 1 | Clinical pipeline report, company report or official report of Spark Therapeutics. |
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