Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
DX5T4D
|
|||
Drug Name |
LY3857210
|
|||
Indication | Pain [ICD-11: MG30-MG3Z] | Phase 2 | [1] | |
Company |
Lilly
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | P2X purinoceptor 7 (P2RX7) | Target Info | Inhibitor | [2] |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Reactome | The NLRP3 inflammasome | |||
WikiPathways | Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways |
References | Top | |||
---|---|---|---|---|
REF 1 | ClinicalTrials.gov (NCT05630196) Randomized, Placebo-Controlled, Phase 2 Clinical Trial to Evaluate LY3857210 for the Treatment of Chronic Low Back Pain. U.S.National Institutes of Health. | |||
REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2023. Adis Insight |
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