| Target's General Information |
| Target ID |
T00884 |
| Target Name |
C-X-C chemokine receptor type 1 (CXCR1) |
| Synonyms |
Interleukin-8 receptor A; IL8RA; IL-8R A; IL-8 receptor type 1; High affinity interleukin-8 receptor A; CXCR-1; CXC-R1; CMKAR1; CDw128a; CD181 |
| Target Type |
Successful |
| Gene Name |
CXCR1 |
| Biochemical Class |
GPCR rhodopsin |
| UniProt ID |
CXCR1_HUMAN |
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People |
| Disease |
Chronic obstructive pulmonary disease |
| Tissue |
Lung tissue |
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 0.12
Z-score: 0.32
P-value: 1.29E-01
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
|
| Disease |
Chronic obstructive pulmonary disease |
| Tissue |
Small airway epithelium |
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 0.07
Z-score: 0.2
P-value: 1.66E-01
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
|
| Target's Expression Profile across Various Tissues of Healthy Individual |
|
| References |
| REF 1 |
Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
|
| REF 2 |
NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.
|
