Target expression details
| Target's General Information | |||||
|---|---|---|---|---|---|
| Target ID | T08910 | ||||
| Target Name | GABA(A) receptor gamma-2 (GABRG2) | ||||
| Synonyms | Gamma-aminobutyric acid receptor subunit gamma-2; GABA(A) receptor subunit gamma-2 | ||||
| Target Type | Successful | ||||
| Gene Name | GABRG2 | ||||
| Biochemical Class | Neurotransmitter receptor | ||||
| UniProt ID | GBRG2_HUMAN | ||||
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People | |||||
| Disease | Epilepsy | ||||
| Example drug | ZK-93423 | Phase 3 | [1], [2], [3], [4] | ||
| Tissue | Peritumoral cortex tissue | ||||
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
|
|||||
| Target's Expression Profile across Various Tissues of Healthy Individual | |||||
|
|||||
| References | |||||
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4346). | ||||
| REF 2 | Abecarnil enhances GABA-induced currents in acutely isolated cerebellar Purkinje cells. Neuropharmacology. 1995 Feb;34(2):157-63. | ||||
| REF 3 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | ||||
| REF 4 | NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.