| Target's General Information |
| Target ID |
T16117 |
| Target Name |
Nitric-oxide synthase brain (NOS1) |
| Synonyms |
Peptidyl-cysteine S-nitrosylase NOS1; Nitric oxide synthase, brain; Neuronal NOS; NOS, type I; NOS type I; NNOS; NC-NOS; N-NOS; BNOS |
| Target Type |
Clinical trial |
| Gene Name |
NOS1 |
| Biochemical Class |
Paired donor oxygen oxidoreductase |
| UniProt ID |
NOS1_HUMAN |
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People |
| Disease |
Asthma |
| Tissue |
Nasal and bronchial airway |
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 0.02
Z-score: 0.07
P-value: 5.20E-01
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
|
| Disease |
Septic shock |
| Tissue |
Whole blood |
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 0.06
Z-score: 0.41
P-value: 1.03E-09
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
|
| Target's Expression Profile across Various Tissues of Healthy Individual |
|
| References |
| REF 1 |
Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
|
| REF 2 |
NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.
|
