Target expression details
| Target's General Information | |||||
|---|---|---|---|---|---|
| Target ID | T19760 | ||||
| Target Name | Mixed lineage kinase 1 (MAP3K9) | ||||
| Synonyms | PRKE1; Mitogen-activated protein kinase kinase kinase 9; MLK1 | ||||
| Target Type | Clinical trial | ||||
| Gene Name | MAP3K9 | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | M3K9_HUMAN | ||||
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People | |||||
| Disease | Asthma | ||||
| Example drug | CEP1347 | Phase 2/3 | [1], [2], [3] | ||
| Tissue | Nasal and bronchial airway | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 0.48 Z-score: 0.76 P-value: 9.49E-06 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Target's Expression Profile across Various Tissues of Healthy Individual | |||||
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| References | |||||
| REF 1 | Targeting the JNK signaling pathway for stroke and Parkinson's diseases therapy. Curr Drug Targets CNS Neurol Disord. 2005 Feb;4(1):63-7. | ||||
| REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | ||||
| REF 3 | NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5. | ||||
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