Target's General Information
Target ID T32282
Target Name Prolactin (PRL)
Synonyms GHA1
Target Type Discontinued
Gene Name PRL
Biochemical Class Somatotropin/prolactin
UniProt ID PRL_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Multiple sclerosis
Example drug NTx-488 Discontinued in Phase 2 [1], [2], [3]
Tissue Spinal cord
Level of differential expression between the patients in the disease section of the tissue section of the tissue adjacent to the disease section Fold-change: -0.36
Z-score: -1.56
P-value: 2.46E-02
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
References
REF 1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028330)
REF 2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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