Target's General Information
Target ID T39123
Target Name G-protein coupled receptor 54 (KISS1R)
Synonyms KiSS-1 receptor GPR54; KISS1R; GPR54
Target Type Discontinued
Gene Name KISS1R
Biochemical Class GPCR rhodopsin
UniProt ID KISSR_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Prostate cancer
Example drug TAK-683 Discontinued in Phase 1 [1], [2]
Tissue Prostate
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.74
Z-score: 0.91
P-value: 2.51E-03
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
References
REF 1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028256)
REF 2 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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