Target expression details
| Target's General Information | |||||
|---|---|---|---|---|---|
| Target ID | T48873 | ||||
| Target Name | Synaptic vesicle amine transporter (SLC18A2) | ||||
| Synonyms | Vesicular amine transporter; Vesicular Monoamine Transporter; VMAT; VAT; Solute carrier family 18 member 2; SLC18A2; Monoamine transporter | ||||
| Target Type | Successful | ||||
| Gene Name | SLC18A2 | ||||
| Biochemical Class | Major facilitator superfamily | ||||
| UniProt ID | VMAT2_HUMAN | ||||
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People | |||||
| Disease | Alzheimer's disease | ||||
| Example drug | AV 133 | Phase 3 | [1], [2] | ||
| Tissue | Entorhinal cortex | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: -0.04 Z-score: -0.11 P-value: 2.69E-02 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027191) | ||||
| REF 2 | NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5. | ||||
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