Target's General Information
Target ID T57718
Target Name Melanoma-associated antigen C2 (MAGEC2)
Synonyms MAGEE1 antigen; MAGEE1; MAGEC2 antigen; MAGE-E1 antigen; MAGE-C2 antigen; Hepatocellular carcinomaassociated antigen 587; Hepatocellular carcinoma-associated antigen 587; HCA587; Cancer/testis antigen 10; CT10
Target Type Clinical trial
Gene Name MAGEC2
Biochemical Class Melanoma associated antigen
UniProt ID MAGC2_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Lung cancer
Example drug CV-9201 Phase 1/2 [1], [2], [3]
Tissue Lung tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.08
Z-score: 0.43
P-value: 1.99E-21
Level of differential expression between the patients in the disease section of the tissue section of the tissue adjacent to the disease section Fold-change: -1.70E-03
Z-score: -0.01
P-value: 1.36E-10
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
References
REF 1 ClinicalTrials.gov (NCT00923312) Trial of an RNActive-Derived Cancer Vaccine in Stage IIIB/IV Non Small Cell Lung Cancer (NSCLC). U.S. National Institutes of Health.
REF 2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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