Target's General Information
Target ID T85158
Target Name Lymphotoxin-alpha (LTA)
Synonyms Tumor necrosis factor ligand superfamily member 1; TNFSF1; TNFB; TNF-beta; LT-alpha
Target Type Clinical trial
Gene Name LTA
Biochemical Class Cytokine: tumor necrosis factor
UniProt ID TNFB_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Rheumatoid arthritis
Example drug Anti-LT alpha Phase 2 [1], [2], [3]
Tissue Synovial tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.19
Z-score: -0.92
P-value: 9.54E-03
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
References
REF 1 Clinical pipeline report, company report or official report of Genentech (2011).
REF 2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.