Target's General Information
Target ID T86014
Target Name Sphingosine kinase 1 (SPHK1)
Synonyms SPK 1; SPK; SPHK1; SK 1; Acetyltransferase SPHK1
Target Type Clinical trial
Gene Name SPHK1
Biochemical Class Kinase
UniProt ID SPHK1_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Arteriosclerosis
Example drug F-12509A Terminated [1], [2], [3]
Tissue Peripheral blood
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.01
Z-score: -0.06
P-value: 7.48E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
References
REF 1 F-12509A, a new sphingosine kinase inhibitor, produced by a discomycete. J Antibiot (Tokyo). 2000 May;53(5):459-66.
REF 2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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