Target's General Information
Target ID T89034
Target Name Plasminogen (PLG)
Synonyms Plasmin
Target Type Successful
Gene Name PLG
Biochemical Class Peptidase
UniProt ID PLMN_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Alzheimer's disease
Example drug Plasminogen concentrate Phase 2/3 [1], [2], [3]
Tissue Entorhinal cortex
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.01
Z-score: -0.09
P-value: 8.61E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
References
REF 1 ClinicalTrials.gov (NCT01554956) Efficacy/Safety of Human Plasminogen Eye Drop in Ligneous Conjunctivitis Patients. U.S. National Institutes of Health.
REF 2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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