Target's General Information
Target ID T92777
Target Name Intestinal maltase-glucoamylase (MGAM)
Synonyms MGAM
Target Type Successful
Gene Name MGAM
Biochemical Class Glycosylase
UniProt ID MGA_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Type 2 diabetes
Example drug Miglitol Approved [1], [2], [3]
Tissue Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.02
Z-score: -0.24
P-value: 4.59E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
References
REF 1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4842).
REF 2 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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