miRNA Details
miRNA General Information | |||||
---|---|---|---|---|---|
miRNA Mature ID | hsa-miR-483-5p | ||||
miRNA Stemloop AC | MI0002467 | ||||
miRNA Stemloop ID | hsa-mir-483 | ||||
Sequence | aagacgggaggaaagaagggag | ||||
TTD Target(s) Regulated by This miRNA | Extracellular signal-regulated kinase 1 (ERK1) | Clinical trial Target | Target Info | [1] | |
Notch-3 receptor (NOTCH3) | Clinical trial Target | Target Info | [2] | ||
Transforming protein RhoA (RHOA) | Discontinued Target | Target Info | [3] | ||
Activated leukocyte cell adhesionmolecule (ALCAM) | Clinical trial Target | Target Info | [4] | ||
Protein(s) Regulated by This miRNA | Creatine kinase B-type | Regulated Protein | [5] | ||
Protein FAM160B2 | Regulated Protein | [6] | |||
Serum response factor | Regulated Protein | [7] | |||
References | |||||
REF 1 | MiR-483-5p suppresses the proliferation of glioma cells via directly targeting ERK1. FEBS Lett. 2012 May 7;586(9):1312-7. | ||||
REF 2 | Characterization of microRNA profile in human cumulus granulosa cells: Identification of microRNAs that regulate Notch signaling and are associated with PCOS. Mol Cell Endocrinol. 2015 Mar 15;404:26-36. | ||||
REF 3 | miR-125a-3p and miR-483-5p promote adipogenesis via suppressing the RhoA/ROCK1/ERK1/2 pathway in multiple symmetric lipomatosis. Sci Rep. 2015 Jul 7;5:11909. | ||||
REF 4 | miR-483-5p promotes invasion and metastasis of lung adenocarcinoma by targeting RhoGDI1 and ALCAM. Cancer Res. 2014 Jun 1;74(11):3031-42. | ||||
REF 5 | Extracellular metabolic energetics can promote cancer progression.Cell. 2015 Jan 29;160(3):393-406. | ||||
REF 6 | Retinoic acid induced 16 enhances tumorigenesis and serves as a novel tumor marker for hepatocellular carcinoma.Carcinogenesis. 2012 Dec;33(12):2578-85. | ||||
REF 7 | MiR-483-5p controls angiogenesis in vitro and targets serum response factor.FEBS Lett. 2011 Oct 3;585(19):3095-100. |
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