miRNA General Information
miRNA Mature ID hsa-miR-522-3p
miRNA Stemloop AC MI0003177
miRNA Stemloop ID hsa-mir-522
Sequence aaaaugguucccuuuagagugu
TTD Target(s) Regulated by This miRNA Transcription factor SOX-2 (SOX2) Literature-reported Target Target Info [1]
Protein(s) Regulated by This miRNA DENN domain-containing protein 2D Regulated Protein [2]
Frataxin, mitochondrial Regulated Protein [3]
Prostaglandin reductase 1 Regulated Protein [4]
References
REF 1 MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis. PLoS One. 2011 Jan 27;6(1):e16617.
REF 2 Downregulation of miR-522 suppresses proliferation and metastasis of non-small cell lung cancer cells by directly targeting DENN/MADD domain containing 2D.Sci Rep. 2016 Jan 19;6:19346.
REF 3 Genetic variations creating microRNA target sites in the FXN 3'-UTR affect frataxin expression in Friedreich ataxia.PLoS One. 2013;8(1):e54791.
REF 4 Novel involvement of miR-522-3p in high-mobility group box 1-induced prostaglandin reductase 1 expression and reduction of phagocytosis.Biochim Biophys Acta Mol Cell Res. 2017 Apr;1864(4):625-633.

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