miRNA Details
| miRNA General Information | |||||
|---|---|---|---|---|---|
| miRNA Mature ID | hsa-miR-558 | ||||
| miRNA Stemloop AC | MI0003564 | ||||
| miRNA Stemloop ID | hsa-mir-558 | ||||
| Sequence | ugagcugcuguaccaaaau | ||||
| TTD Target(s) Regulated by This miRNA | Heparanase (HPSE) | Successful Target | Target Info | [1] | |
| Prostaglandin G/H synthase 2 (COX-2) | Successful Target | Target Info | [2] | ||
| Protein(s) Regulated by This miRNA | Serine/threonine-protein kinase LMTK1 | Regulated Protein | [3] | ||
| References | |||||
| REF 1 | miRNA-558 promotes gastric cancer progression through attenuating Smad4-mediated repression of heparanase expression. Cell Death Dis. 2016 Sep 29;7(9):e2382. | ||||
| REF 2 | MicroRNA-558 regulates the expression of cyclooxygenase-2 and IL-1-induced catabolic effects in human articular chondrocytes. Osteoarthritis Cartilage. 2013 Jul;21(7):981-9. | ||||
| REF 3 | Downregulation of AATK mediates microRNA-558-induced resistance of A549 cells to radiotherapy.Mol Med Rep. 2016 Sep;14(3):2846-52. | ||||
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