miRNA General Information
miRNA Mature ID hsa-miR-613
miRNA Stemloop AC MI0003626
miRNA Stemloop ID hsa-mir-613
Sequence aggaauguuccuucuuugcc
TTD Target(s) Regulated by This miRNA Cyclin-dependent kinase 4 (CDK4) Successful Target Target Info [1]
ATP-binding cassette transporter A1 (ABCA1) Successful Target Target Info [2]
Brain-derived neurotrophic factor (BDNF) Clinical trial Target Target Info [3]
Oxysterols receptor LXR-alpha (NR1H3) Patented-recorded Target Target Info [4]
Protein(s) Regulated by This miRNA Metalloproteinase inhibitor 3 Regulated Protein [5]
References
REF 1 MiR-613 induces cell cycle arrest by targeting CDK4 in non-small cell lung cancer. Cell Oncol (Dordr). 2016 Apr;39(2):139-47.
REF 2 miR-613 regulates cholesterol efflux by targeting LXR and ABCA1 in PPAR activated THP-1 macrophages. Biochem Biophys Res Commun. 2014 Jun 6;448(3):329-34.
REF 3 MicroRNA-613 regulates the expression of brain-derived neurotrophic factor in Alzheimer's disease. Biosci Trends. 2016 Nov 15;10(5):372-377.
REF 4 MicroRNA hsa-miR-613 targets the human LXR gene and mediates a feedback loop of LXR autoregulation. Mol Endocrinol. 2011 Apr;25(4):584-96.
REF 5 Integrated analyses of microRNA and mRNA expression profiles in aggressive papillary thyroid carcinoma.Mol Med Rep. 2013 Nov;8(5):1353-8.

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