| Patent(s) and the Corresponding Patented Drug(s) |
Top |
| World Intellectual Property Organization (WIPO) |
| Patent ID |
WO2012107499 |
| Title |
Lysine Demethylase Inhibitors for Myeloproliferative or Lymphoproliferative Diseases or Disorders. |
| Abstract |
The present invention relates to methods and compositions for the treatment or prevention of diseases and disorder associated with myeloproliferative and lymphoproliferative disorders. In particular, the invention relates to an LSD1 inhibitor for use in treating or preventing diseases and disorder associated with myeloproliferative and lymphoproliferative disorders. |
| Applicant(s) |
Oryzon Genomics Sa |
| Representative Drug(s) |
D01CIK |
Drug Info
|
N.A. |
Click to Show More |
[1] |
|
2
|
D07MQD
|
Drug Info
|
N.A.
|
[1] |
|
3
|
D0UE4K
|
Drug Info
|
N.A.
|
[1] |
| Patent ID |
WO2012107498 |
| Title |
Lysine Demethylase Inhibitors for Myeloproliferative Disorders. |
| Abstract |
The invention relates to methods and compositions for the treatment or prevention of diseases and disorders associated with myeloproliferative disorders. In particular, the invention relates to an LSD 1 inhibitor for use in treating or preventing Philadelphia chromosome negative myeloproliferative disorders. |
| Applicant(s) |
Oryzon Genomics, Sa |
| Representative Drug(s) |
D01CIK |
Drug Info
|
N.A. |
Click to Show More |
[1] |
|
2
|
D07MQD
|
Drug Info
|
N.A.
|
[1] |
|
3
|
D0UE4K
|
Drug Info
|
N.A.
|
[1] |
| Patent ID |
WO2011030108 |
| Title |
Jmjd2 Demethylase Inhibitors. |
| Abstract |
The present invention relates to inhibitors of JMJD2 subfamily histone lysyl demethylase enzymes. In particular, the invention relates to compounds that are capable of inhibiting a JMJD2 subfamily histone lysyl demethylase without also inhibiting a 2-oxoglutarate dependent oxygenase that is not a JMJD2 subfamily histone lysyl demethylase, and to assays for the identification of inhibitors of JMJD2 subfamily histone lysyl demethylase enzymes. |
| Applicant(s) |
Isis Innovation Limited |
| Representative Drug(s) |
D05PXW |
Drug Info
|
N.A. |
Click to Show More |
[2] |
|
2
|
D09YFD
|
Drug Info
|
N.A.
|
[2] |
|
3
|
D0JQ9Z
|
Drug Info
|
N.A.
|
[2] |
|
4
|
D0X2AU
|
Drug Info
|
N.A.
|
[2] |
|
5
|
D0X6SJ
|
Drug Info
|
N.A.
|
[2] |
| Patent ID |
WO2010043721 |
| Title |
Oxidase Inhibitors and Their Use. |
| Abstract |
The invention relates to phenylcyclopropylamine acetamide derivatives and their use in treating diseases. |
| Applicant(s) |
Oryzon Genomics Sa |
| Representative Drug(s) |
D0UL9U |
Drug Info
|
N.A. |
[1] |
| Patent ID |
WO2015181380 |
| Title |
Cyclopropylamine Compounds As Histone Demethylase Inhibitors. |
| Abstract |
The present disclosure relates to cyclopropyl compounds of general formula (I), wherein R1, and R2 are as defined in the specification. The present application also relates to pharmaceutical compositions containing such compounds and to their use in therapy. |
| Applicant(s) |
Ieo - Istituto Europeo Di Oncologia Srl |
| United States Patent and Trademark Office (USPTO) |
| Patent ID |
US20130137720 |
| Title |
Histone Demethylase Inhibitors and Methods for Using The Same. |
| Representative Drug(s) |
D09NCT |
Drug Info
|
IC50 = 4300 nM |
[2] |
| European Patent Office (EPO) |
| Patent ID |
EP2177502 |
| Title |
Preparation of N-(2 Phenylcyclopropyl) Amino Acid Derivatives for Treatment of Cancer. |
| Applicant(s) |
Oryzon Genomics Sa, Spain |
| Representative Drug(s) |
D0UL9U |
Drug Info
|
N.A. |
[1] |
| Japan Patent Office (JPO) |
| Patent ID |
JP2011168581 |
| Title |
Preparation of Hydroxamic Acid Derivatives As Jhdm Inhibitors. |
| Representative Drug(s) |
D0MJ4L |
Drug Info
|
IC50 = 3000 nM |
[2] |
