| Patent(s) and the Corresponding Patented Drug(s) |
Top |
| World Intellectual Property Organization (WIPO) |
| Patent ID |
WO2012070024 |
| Title |
Carbonic Anhydrase Inhibitors with Antimetastatic Activity. |
| Abstract |
Compositions for the treatment of cancer comprising coumarin and thiocoumarin derivatives of Formulas I- XII are disclosed. Said derivatives preferentially inhibit carbonic anhydrase IX and XII (which are associated with hypoxic and metastatic tumours) over inhibiting carbonic anhydrase I and II activity. The compositions therefore are suited for treatment of hypoxic or metastatic cancers due to this selective mechanism of action. |
| Applicant(s) |
Metasignal Therapeutics Inc |
| Representative Drug(s) |
D02VIR |
Drug Info
|
N.A. |
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[1] |
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2
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D0CE8B
|
Drug Info
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N.A.
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[1] |
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3
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D0F8XZ
|
Drug Info
|
N.A.
|
[1] |
| Patent ID |
WO2010139678 |
| Title |
Treatment of Mammalian Disorders Mediated By Alpha-Carbonic Anhydrase Isoforms. |
| Abstract |
The present invention pertains to 4-(4-methyliperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin- 3-yl)pyrimidin-2-ylamino)phenyl]-benzamide or a pharmaceutically acceptable salt thereof, or 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino}-/-[5-(4--methyl-1H-imidazol-1-yl)-3-(trifluoro- methy!)phenyl] benzamide or a pharmaceutically acceptable salt thereof, for the treatment of disorders mediated by alpha-carbonic anhydrase isoforms selected from intraocular hypertension (glaucoma), epilepsy, Lennox-Gastaut syndrome, altitude sickness, headaches, neurological disorders and obesity. |
| Applicant(s) |
University of Tampere |
| Representative Drug(s) |
D07DGA |
Drug Info
|
N.A. |
Click to Show More |
[1] |
|
2
|
D0OE4F
|
Drug Info
|
N.A.
|
[1] |
| Patent ID |
WO2015063249 |
| Title |
Modulator of Bone Mineralization Based On A Combination of Polyphosphate/Carbonate and Carbonic Anhydrase Activators. |
| Abstract |
The invention relates to the application of a combination of at least one inorganic polyphosphate (polyP) and/or a salt of said polyP and calcium [polyP (Ca2+ salt)] and bicarbonate/calcium-carbonate, optionally together with at least one carbonic anhydrase activatora carbonic anhydrase (CA) activator or a material comprising these combinations for the treatment of bone defects, such as, for example, for a prophylaxis and treatment of osteoporosis and other bone diseases. The combinations, e.g. of a CA activator and polyP or polyP (Ca2+ complex) can be used both as a drug or food supplement, and as a material to be injected into bone tissue. |
| Applicant(s) |
Werner E. G. MLLER |
| Patent ID |
WO2015025283 |
| Title |
Dual Action Carbonic Anhydrase Inhibitors. |
| Abstract |
The present invention is directed to novel carbonic anhydrase IX inhibitors comprising a nitroimidazole moiety substituted with a heterocycle or phosphinate and having sulfonamide, sulfamate or sulfamide groups. The present invention is also related to the use of these novel carbonic anhydrase IX inhibitors in cancer treatment, especially radiotherapy and chemotherapy and the use in treatment of infections. |
| Applicant(s) |
Stichting Maastricht Radiation Oncology "Maastro - Clinic" |
| Patent ID |
WO2013050426 |
| Title |
Carbonic Anhydrase Inhibitor Comprising A Dithiocarbamate. |
| Abstract |
A carbonic anhydrase inhibitor which comprises a compound of general formula: R1R2N-CS2-M+ for use in the treatment of microbial infection, eye disease or cancer; wherein R1 and R2 are each independently selected from H or an organic substituent, or together form a ring, and optionally contain one or more heteroatoms; wherein R and R2 together comprise at least 5 carbon atoms or at least 2 carbon atoms and a heteroatom, or R2 comprises at least 4 carbon atoms; and wherein M+ comprises a monovalent cation. |
| Applicant(s) |
Universitetet I Oslo |
| Patent ID |
WO2008071421 |
| Title |
Nitrate Esters of Carbonic Anhydrase Inhibitors. |
| Abstract |
Nitroderivatives of carbonic anhydrase inhibitors having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma, ocular hypertension, age-related macular degeneration, diabetic macular edema, diabetic retinopathy, hypertensive retinopathy and retinal vasculopathies, cancer, epilepsy, high-altitude disorders and neuromuscular diseases. |
| Applicant(s) |
Nicox S.A |
| United States Patent and Trademark Office (USPTO) |
| Patent ID |
US2014303390 |
| Title |
Carbonic Anhydrase Inhibitors and Method of Their Production. |
| Patent ID |
US2017056350 |
| Title |
Targeted Treatment of Anerobic Cancer. |
| Patent ID |
US20160279084 |
| Title |
Targeted Treatment of Anerobic Cancer. |
| Patent ID |
US2016015730 |
| Title |
Treatment of Pulmonary Hypertension with Carbonic Anhydrase Inhibitors. |
| Patent ID |
US2013336923 |
| Title |
Carbonic Anhydrase Ix (G250) Antibodies and Methods of Use Thereof. |
| Patent ID |
US2013053392 |
| Title |
Carbonic Anhydrase Inhibitors. |
| Patent ID |
US2011091576 |
| Title |
Therapeutic and Prophylactic Uses of Cell Specific Carbonic Anhydrase Enzymes In Treating Aging Disorders Due To Oxidative Stress and As Growrh Factors of Stem Cells. |
| European Patent Office (EPO) |
| Patent ID |
EP2823826 |
| Title |
Inhibitors of Carbonic Anhydrase Ix. |
| Japan Patent Office (JPO) |
| Patent ID |
JP2012250949 |
| Title |
Combination of Adenosine Derivative and Carbonic Anhydrase Inhibitor and Beta-Receptor Blocker. |
| China National Intellectual Property Administration (CNIPA) |
| Patent ID |
CN106822174 |
| Title |
Thermosensitive Cyclodextrin-Based Carbonic Anhydrase Inhibitor and Preparation Method Thereof. |
| Applicant(s) |
Univ Shanghai |
| Intellectual Property Office in India (IP India) |
| Patent ID |
IN1948MU2015 |
| Title |
Method for The Synthesis of Bifunctional Cerium Oxide Nanoparticle with Enhanced Antioxidant and Carbonic Anhydrase Inhibitory Activity. |
| Canadian Intellectual Property Office (CIPO) |
| Patent ID |
CA2948743 |
| Title |
Antibody Binding To Carbonic Anhydrase and Use Thereof. |
| Patent ID |
CA2856812 |
| Title |
Carbonic Anhydrase Inhibitors with Antimetastatic Activity. |
| Intellectual Property Office of Australia (IP Australia) |
| Patent ID |
AU2011250022 |
| Title |
Novel Antibody To A Carbonic Anhydrase. |
