Target and Its Patented Drug(s)
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T59459 | Target Info | |||
| Target Name | JNK-interacting protein 1 peptide (pepJIP1) | ||||
| Synonyms | PRKM8IP; Mitogen-activated protein kinase 8-interacting protein 1; JNK-interacting protein 1; JNK MAP kinase scaffold protein 1; JIP1; JIP-1; Islet-brain 1; IB1; IB-1; C-Jun-amino-terminal kinase-interacting protein 1 | ||||
| Target Type | Patented-recorded Target | ||||
| Gene Name | MAPK8IP1 | ||||
| UniProt ID | |||||
| Patent(s) and the Corresponding Patented Drug(s) | Top | ||||
|---|---|---|---|---|---|
| World Intellectual Property Organization (WIPO) | |||||
| Patent ID | WO2010108155 | ||||
| Title | Modulators of Cystic Fibrosis Transmembrane Conductance Regulator. | ||||
| Abstract | This invention relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R is COOH or CH2OH. | ||||
| Applicant(s) | Vertex Pharmaceuticals Incorporated | ||||
| Representative Drug(s) | D0ID4H | Drug Info | IC50 = 1000 nM | [1] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | c-Jun N-terminal kinase inhibitors: a patent review (2010 - 2014).Expert Opin Ther Pat. 2015;25(8):849-72. | ||||
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