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Target General Information |
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Target ID |
T64205 |
Target Info
|
Target Name |
Signal transducer and activator of transcription 1 (STAT1) |
Synonyms |
Transcription factor ISGF-3 components p91/p84; Signal transducers and activators of transcription factor; Signal transducer and activator of transcription 1-alpha/beta; STAT-1; P91 |
Target Type |
Patented-recorded Target |
Gene Name |
STAT1 |
Biochemical Class |
Transcription factor |
UniProt ID |
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Patent(s) and the Corresponding Patented Drug(s) |
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World Intellectual Property Organization (WIPO) |
Patent ID |
WO2006071812 |
Title |
Platinum Iv Complex Inhibitor. |
Abstract |
The invention disclosed herein provides methods for diagnosing and treating diseases and/or conditions associated with dysregulated Stat3-mediated activity. |
Applicant(s) |
H. Lee Moffitt Cancer Center and Research Institute |
Representative Drug(s) |
D01BVU |
Drug Info
|
IC50 = 4100 nM |
[1] |
References |
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REF 1 |
A STAT inhibitor patent review: progress since 2011.Expert Opin Ther Pat. 2015;25(12):1397-421.
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