Target and Its Patented Drug(s)
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T67054 | Target Info | |||
| Target Name | 5-HT 1 receptor (5HT1R) | ||||
| Synonyms | Serotonin receptor 1; 5-hydroxytryptamine receptor 1; 5-HT1 receptor | ||||
| Target Type | Patented-recorded Target | ||||
| Gene Name | NO-GeName | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Patent(s) and the Corresponding Patented Drug(s) | Top | ||||
|---|---|---|---|---|---|
| World Intellectual Property Organization (WIPO) | |||||
| Patent ID | WO2016187377 | ||||
| Title | Compounds and Methods for Modulating Serotonin Receptors In The Periphery. | ||||
| Abstract | This invention relates to, in part, compositions and methods that are useful for, inter alia, the treatment of various diseases, including those linked to binding at a serotonin receptor in the Gl tract. | ||||
| Applicant(s) | Northeastern University | ||||
| United States Patent and Trademark Office (USPTO) | |||||
| Patent ID | US20160244429 | ||||
| Title | Substituted Piperazine Compounds and Methods of Use Thereof. | ||||
| Representative Drug(s) | D0M9LM | Drug Info | Ki = 0.5 nM | Click to Show More | [1] |
| 2 | D0T7HK | Drug Info | Ki = 0.53 nM | [1] | |
| 3 | D0F9TY | Drug Info | Ki = 4.2 nM | [1] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | 5-HT1A receptor ligands and their therapeutic applications: review of new patents.Expert Opin Ther Pat. 2018 Sep;28(9):679-689. | ||||
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