Target and Its Patented Drug(s)
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T89360 | Target Info | |||
| Target Name | Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) | ||||
| Synonyms | IMPDH-II; IMPDH 2; IMPD2; IMPD 2; IMP dehydrogenase 2 | ||||
| Target Type | Successful Target | ||||
| Gene Name | IMPDH2 | ||||
| Biochemical Class | CH-OH donor oxidoreductase | ||||
| UniProt ID | |||||
| Patent(s) and the Corresponding Patented Drug(s) | Top | ||||
|---|---|---|---|---|---|
| United States Patent and Trademark Office (USPTO) | |||||
| Patent ID | US20026399773 | ||||
| Title | Compounds Derived From An Amine Nucleus That Are Inhibitors of Impdh Enzyme. | ||||
| Applicant(s) | Bristol-Myers Squibb Co | ||||
| Representative Drug(s) | D09HTY | Drug Info | IC50 = 12 nM | [1] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors: a patent and scientific literature review (2002-2016).Expert Opin Ther Pat. 2017 Jun;27(6):677-690. | ||||
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