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| Protein General Information (TTD Target) |
Top |
| Full Name |
GTPase HRas (HRAS)
|
Literature-reported
|
Target Info
|
| UniProt ID |
RASH_HUMAN
|
| Gene Name |
HRAS
|
| Gene ID |
3265
|
| Interacting TTD Target Information |
Top |
| Interacting Successful Target(s) |
Serine/threonine-protein kinase B-raf (BRAF) |
Target Info
|
PPI Info
|
[1] |
| Interacting Clinical trial Target(s) |
Proto-oncogene c-RAF (c-RAF) |
Target Info
|
PPI Info
|
[2] |
| Interacting Patented-recorded Target(s) |
Galectin-1 (LGALS1) |
Target Info
|
PPI Info
|
[3] |
| Interacting Literature-reported Target(s) |
GTPase activating protein (RASA1) |
Target Info
|
PPI Info
|
[4] |
| References |
Top |
| REF 1 |
Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles. Oncotarget. 2016 May 3;7(18):26628-52.
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| REF 2 |
Stimulation of Ras guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) upon tyrosine phosphorylation by the Cdc42-regulated kinase ACK1. J Biol Chem. 2000 Sep 22;275(38):29788-93.
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| REF 3 |
Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation. Oncogene. 2001 Nov 8;20(51):7486-93.
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| REF 4 |
EGFR phosphorylates FAM129B to promote Ras activation. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):644-9.
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