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| Protein General Information |
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| Full Name |
E3 ubiquitin-protein ligase RNF168 (RNF168)
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| UniProt ID |
RN168_HUMAN
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| Gene Name |
RNF168
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| Gene ID |
165918
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| Interacting TTD Target Information |
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| Interacting Clinical trial Target(s) |
Lysine-specific histone demethylase 1 (LSD) |
Target Info
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PPI Info
|
[1] |
| Interacting Literature-reported Target(s) |
Tumor suppressor p53-binding protein 1 (TP53BP1) |
Target Info
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PPI Info
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[2] |
| References |
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| REF 1 |
The histone demethylase LSD1/KDM1A promotes the DNA damage response. J Cell Biol. 2013 Nov 11;203(3):457-70.
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| REF 2 |
Modulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damage. Nucleic Acids Res. 2015 Jul 13;43(12):5936-47.
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