Prodrug Information
| Prodrug General Information | Top | |||||
|---|---|---|---|---|---|---|
| Prodrug ID |
DM9S7X
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| Prodrug Name |
PMID26729077-Compound-26
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| Indication | Inflammation [ICD-11: 1A00-CA43.1] | Investigative | [1] | |||
| Activation |
Prodrug 
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Parent Drug 
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| 2D MOL | 2D MOL 3D MOL | |||||
| Prodrug Strategy |
Classical prodrug strategy
[Carrier linked prodrug]
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| Improved property |
Increase solubility
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[1] | ||||
| Description |
PMID26729077-Compound-26 shows 64-fold solubility and greater skin permeation than quercetin.
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[1] | ||||
| Parent Drug General Information | Top | |||||
|---|---|---|---|---|---|---|
| Parent Drug ID |
D0ULR5
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| Parent Drug Name |
Quercetin
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| Synonyms |
A-8821; CQ0011; Cyanidelonon 1522; Cyanidenolon 1522; Enicostemma Littorale Blume; Ericin; Flavin meletin; K00029; Kvercetin; Kvercetin [Czech]; LDN 0052529; LDN-0052529; LIM-5662; LK87600000; LNS-5662; Meletin; N1841; Q 0125; Q0025; Quer; Quercetin; Quercetin-Sophoretin; Quercetine; Quercetol; Quercitin; Quertin; Quertine; Ritacetin; Sophoretin; Xanthaurine; (+)-3,3',4',5,7-Pentahydroxyflavone; 3',4',5,7-Tetrahydroxyflavan-3-ol; 3',4',5,7-pentahydroxy-Flavone; 3',4',5,7-tetrahydroxyflavon-3-ol; 3',5,7-Tetrahydroxyflavan-3-ol; 3,3',4',5,7-Pentahydroxyflavone; 3,3',4',5,7-pentahydroxy-Flavone; 3,3',4,5,7-Pentahydroxyflavone; 3,4',5,5',7-pentahydroxy-Flavone; 3,4',5,7-Pentahydroxyflavone; 3,5,7,3',4'-Pentahydroxyflavon; 3,5,7,3',4'-Pentahydroxyflavone; 3,7,3',4'-Pentahydroxyflavone
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| Formula |
C15H10O7
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| Canonical SMILES |
C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O
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| InChI |
1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
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| InChIKey |
REFJWTPEDVJJIY-UHFFFAOYSA-N
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| CAS Number |
CAS 117-39-5
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| PubChem Compound ID | ||||||
| ChEBI ID |
CHEBI:16243
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| References | Top | |||||
|---|---|---|---|---|---|---|
| REF 1 | In vitro evaluation of quercetin-3-O-acyl esters as topical prodrugs. Int J Pharm. 2007 May 24;336(2):257-62. | |||||
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