Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T03644 | Target Info | |||
| Target Name | Synuclein alpha (SNCA) | ||||
| Synonyms |
PARK1; Non-A4 component of amyloid precursor; Non-A beta component of AD amyloid; NACP; Alpha-synuclein
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| Target Type | Clinical trial Target | ||||
| Gene Name | SNCA | ||||
| Biochemical Class | Synuclein | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Brilliant Blue R
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Investigative | Compound Info | ||
| Synonyms |
Acid Blue 83; COOMASSIE BRILLIANT BLUE R; AcidBlue83; UNII-TKL1K0PT9A; TKL1K0PT9A; Coomassie Brilliant Blue R250; CHEMBL4279842; Acid Cyanine 6B; Solar Cyanine 6B; MFCD00041762; Alizarin Rubinol 5G; Coomassie Brilliant Blue R-250; Coomassie Brilliant Blue R250 (C.I. 42660); Brilliant Blue R, pure; C.I. Acid Blue 83; Brilliant indocyanin 6B; Eriosin Brilliant Cyanine 6B; bril-liant blue r; EINECS 228-060-5; Brilliant Blue R soln.; Brilliant Blue R-250; C45H44N3NaO7S2; C45H44N3O7S2Na; CBB R250; SCHEMBL1925726; CBB R-250; DTXSID80910613; BDBM50464535; AKOS015902422; Brilliant Blue R solution, Ready-to-Use; AS-13946; SC-95729; B3194; FT-0624039; Q418516; Brilliant blue R; Coomassie brilliant blue R-250; Acid Blue 83; CI 42660
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| Activity |
IC50 = 322000 nM
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[1] | |||
| References | Top | ||||
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| REF 1 | A routinely used protein staining dye acts as an inhibitor of wild type and mutant alpha-synuclein aggregation and modulator of neurotoxicity. Eur J Med Chem. 2018 Jan 1;143:1174-1184. | ||||
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