Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T12797 | Target Info | |||
| Target Name | Bcl-2-related protein A1 (BCL2A1) | ||||
| Synonyms |
Protein GRS; Protein BFL-1; Hemopoietic-specific early response protein; HBPA1; GRS; Bcl2-L-5; Bcl-2-like protein 5; BFL1; BCL2L5
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| Target Type | Patented-recorded Target | ||||
| Gene Name | BCL2A1 | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 3 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
1-(3,4-Dichlorophenyl)-3-chloro-4-[benzylamino]azoline-2,5-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1271992; DTXSID80360811; ZINC939247; STL333085; AKOS002314749; MCULE-2742925695; ST50322484; SR-01000236068; SR-01000236068-1
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
3-Chloro-1-(3,4-dichlorophenyl)-4-piperidin-1-ylpyrrole-2,5-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1271938; MLS-0066990.0001; CBMicro_048117; SCHEMBL13912138; BDBM39119; cid_1180675; ZINC939261; STL332374; AKOS002266960; MCULE-8172101525; BIM-0048210.P001; ST50183359; SR-01000205839; SR-01000205839-1; 1-(3,4-dichlorophenyl)-4-chloro-3-piperidylazoline-2,5-dione; 3-chloranyl-1-(3,4-dichlorophenyl)-4-piperidin-1-yl-pyrrole-2,5-dione; 3-chloro-1-(3,4-dichlorophenyl)-4-(1-piperidinyl)pyrrole-2,5-dione; 3-chloro-1-(3,4-dichlorophenyl)-4-(piperidin-1-yl)-1H-pyrrole-2,5-dione; 3-chloro-1-(3,4-dichlorophenyl)-4-(piperidino)-1H-pyrrole-2,5-dione; 3-chloro-1-(3,4-dichlorophenyl)-4-piperidino-3-pyrroline-2,5-quinone
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
3-Chloro-1-(3,4-dichlorophenyl)-4-(pyrrolidino)-1H-pyrrole-2,5-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1271937; SCHEMBL13912151; BDBM50330081; MLS-0067126.0001
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Inhibition of Bfl-1 with N-aryl maleimides. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6560-4. | ||||
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