Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T13127 | Target Info | |||
| Target Name | Farnesyl protein transferase (Ftase) | ||||
| Synonyms |
Ras proteins prenyltransferase; Protein farnesyltransferase; Ftase; CAAX farnesyltransferase
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|
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| Target Type | Successful Target | ||||
| Gene Name | FNTB; FNTA | ||||
| Biochemical Class | Alkyl aryl transferase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 117 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Desloratadine
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|
Approved | Compound Info | ||
| Synonyms |
Aerius; Allex; Azomyr; Claramax; Clarinex; Denosin; Desalex; Descarboethoxyloratadine; Descarboethoxyoratidine; Desloratidine; Neoclarityn; Opulis; Clarinex RediTabs; Desloratadine [USAN]; Essex brand of desloratadine; Schering brand of desloratadine; Sch 34117; Aerius (TN); Claramax (TN); Clarinex (TN); NeoClarityn (TN); Sch-34117; Schering-Plough brand of desloratadine; Desloratadine (USAN/INN); 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine; 8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
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|
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| Activity |
IC50 ~ 65000 nM
|
[1] | |||
| Compound Name |
B-581
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|
Terminated | Compound Info | ||
| Synonyms |
149759-96-6; B581; FTase Inhibitor I; B 581; B-581; CHEMBL91722; CHEBI:83620; N-[2(S)-(2(R)-2-Amino-3-mercaptopropylamino)-3-methylbutyl]-L-phenylalanyl-L-methionine trifluoroacetate salt; (S)-2-((S)-2-((S)-2-((R)-2-amino-3-mercaptopropylamino)-3-methylbutylamino)-3-phenylpropanamido)-4-(methylthio)butanoic acid; CBiol_001875; H-Cys-psi(CH2NH)Val-psi(CH2NH)Phe-Met-OH; AC1L31RF; BSPBio_001466; KBioSS_000186; KBioGR_000186; SCHEMBL2723960; KBio3_000372; KBio2_005322; KBio2_000186; KBio3_000371; KBio2_002754; CTK8E9094
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|
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| Activity |
IC50 = 50000 nM
|
[2] | |||
| Compound Name |
Gliotoxin
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|
Terminated | Compound Info | ||
| Synonyms |
gliotoxin; 67-99-2; Aspergillin; UNII-5L648PH06K; CCRIS 4025; Gliotoxin from Gliocladium fimbriatum; NSC 102866; BRN 0050675; AI3-62383; CHEBI:5385; CHEMBL331627; S.N. 12870; Gliotoxin, Gladiocladium fimbriatum; 5L648PH06K; 10H-3,10a-Epidithiopyrazino(1,2-a)indole-1,4-dione, 2,3,5a,6-tetrahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-; Gliotoxins; 10H-3,10a-Epidithiopyrazino(1,2-a)indole-1,4-dione, 2,3,5a,6-hydroxy-3- (hydroxymethyl)-2-methyl-, (3R-(3-alpha,5a-beta,6-beta,10a-alpha))-
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|
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| Activity |
IC50 = 80000 nM
|
[3] | |||
| Compound Name |
(2S)-2-[3-(Dibenzofuran-4-yl)-4-cyano-5-(isopropylthio)thiophene-2-ylcarbonylamino]-4-(methylthio)butanoic acid methyl ester
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3133576
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|
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
N'-[2-(Methylthio)ethyl]-N'-(ethoxycarbonylmethyl)-3-(4-chlorophenyl)-4-cyano-5-(isopropylthio)-2-thiophenecarbohydrazide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3133568
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|
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
4-Cyano-3-(2,4-dimethoxyphenyl)-5-propan-2-ylsulfanylthiophene-2-carboxylic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3221160
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|
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
Methyl (2R)-2-[[3-(4-chlorophenyl)-4-cyano-5-propan-2-ylsulfanylthiophene-2-carbonyl]amino]-4-methylsulfanylbutanoate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL569400
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|
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
Ethyl 4-cyano-3-(2,4-dimethoxyphenyl)-5-propan-2-ylsulfanylthiophene-2-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3221159
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|
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
Methyl (2S)-2-[[(2S,3S)-2-[(4-cyano-3-phenyl-5-propan-2-ylsulfanylthiophene-2-carbonyl)amino]-3-methylpentanoyl]amino]-4-methylsulfanylbutanoate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3133585
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|
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
2-[(2-Methoxyphenyl)acetyl]-4alpha,9alpha-ethano-5-hydroxy-9-phenyl-2,3,4,9-tetrahydro-1H-benzo[f]isoindole-3abeta(9abetaH)-carboxylic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL53295; BDBM50088006; RPR-131168
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| Activity |
Ki = 50000 nM
|
[6] | |||
| Compound Name |
4-Cyano-5-propan-2-ylsulfanyl-3-(3,4,5-trimethoxyphenyl)thiophene-2-carboxylic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3221148
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|
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
4-Cyano-3-(3,5-dimethoxyphenyl)-5-propan-2-ylsulfanylthiophene-2-carboxylic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3221156
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|
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
Ethyl 4-cyano-3-(3-methoxyphenyl)-5-propan-2-ylsulfanylthiophene-2-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3221139
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|
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
3-(2-Methoxyphenyl)-4-cyano-5-(isopropylthio)thiophene-2-carboxylic acid (1l)
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3221144; BDBM238363
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|
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
Methyl (2S)-2-[[5-butan-2-ylsulfanyl-3-(4-chlorophenyl)-4-cyanothiophene-2-carbonyl]amino]-4-methylsulfanylbutanoate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3133581
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|
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
2-(1H-Indol-3-yl)-N-isopropyl-N-pyridin-4-ylmethyl-acetamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL352341; SCHEMBL6667785; BDBM50098017; N-(4-Pyridinylmethyl)-N-isopropyl-1H-indole-3-acetamide
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|
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
N-(1-Adamantyl)-3-(4-chlorophenyl)-4-cyano-5-(isopropylthio)-2-thiophenecarboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3133570
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|
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
Ethyl 3-(4-chlorophenyl)-4-cyano-5-propan-2-ylsulfanylthiophene-2-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL581850; SCHEMBL16798046; ZINC1037674; CCG-252509; MCULE-1632726050
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|
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
2-(1-Butyl-2-phenyl-1H-indol-3-yl)-N-isopropyl-N-pyridin-4-ylmethyl-acetamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL168469; BDBM50098031; N-(4-Pyridinylmethyl)-N-isopropyl-1-butyl-2-phenyl-1H-indole-3-acetamide
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|
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(2R,3R,5S)-5-Tert-butyl-2-(4-chlorophenyl)-1-(2-methylphenyl)sulfonylpyrrolidine-3-carboxylic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3218389; P5-H6; BDBM50496835
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|
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
4-Cyano-3-(3,4-dimethoxyphenyl)-5-propan-2-ylsulfanylthiophene-2-carboxylic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3221152
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|
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
Ethyl 4-cyano-3-phenoxy-5-propan-2-ylsulfanylthiophene-2-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3221169
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|
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
2-[2-[2-[(10R,13S,17R)-17-Hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-2-oxoethyl]butanedioic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL341962; BDBM50067828
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|
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| Activity |
IC50 = 50000 nM
|
[9] | |||
| Compound Name |
(S)-4-Methyl-2-({4-[(pyridin-4-ylmethyl)-amino]-biphenyl-2-carbonyl}-amino)-pentanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL26720; GGTI-2139; BDBM50076132
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|
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| Activity |
IC50 = 50000 nM
|
[10] | |||
| Compound Name |
Ethyl 4-cyano-3-(2-hydroxyphenyl)-5-propan-2-ylsulfanylthiophene-2-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3221145
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|
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
Ethyl 4-cyano-3-(4-methoxyphenyl)-5-propan-2-ylsulfanylthiophene-2-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3221135
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|
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
Methyl (2S)-2-[benzoyl-[1-(1,3-thiazole-4-carbonyl)piperidin-4-yl]amino]-4-methylsulfanylbutanoate;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL542985
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|
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| Activity |
IC50 = 52500 nM
|
[11] | |||
| Compound Name |
Ggti-2418
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Investigative | Compound Info | ||
| Synonyms |
UNII-M67G28K74K; CHEMBL3218390; M67G28K74K; 501010-06-6 (free acid); GGTI 2418; Geranylgeranyl transferase inhibitor-2148; SCHEMBL16112087; SCHEMBL19236435; DTXSID80198212; EX-A3132; BDBM50496833; MFCD25976818; SB17250; BS-17117; HY-16231; CS-0006195; A13112; Z-3149; Q27283547
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| Activity |
IC50 = 53000 nM
|
[8] | |||
| Compound Name |
3-Oxo-2-(phosphonomethyl)-3-[[(6E)-3,3,7,11-tetramethyldodeca-6,10-dienyl]amino]propanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL99145; SCHEMBL8967850; SCHEMBL8967871; BDBM50453721
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|
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| Activity |
IC50 = 55000 nM
|
[12] | |||
| Compound Name |
[(3Z)-4-[4-(Dimethylamino)pyridin-1-ium-1-yl]-2-ethoxycarbonyl-5-oxo-5-(3-oxo-4H-1,4-benzoxazin-6-yl)penta-1,3-dienylidene]azanide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2435015; BDBM50493659
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| Activity |
IC50 = 55220 nM
|
[13] | |||
| Compound Name |
1-[4-(8-Methoxy-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidin-1-yl]ethanone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL131155; SCHEMBL8878769; BDBM50007456; 1-[4-(8-Methoxy-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-ethanone; 5,6-Dihydro-11-(1-acetyl-4-piperidinylidene)-8-methoxy-11H-benzo[5,6]cyclohepta[1,2-b]pyridine
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|
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| Activity |
IC50 = 56000 nM
|
[14] | |||
| Compound Name |
2-Ethyl-butyric acid 2-((10R,13S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl ester
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL141968; BDBM50067853
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|
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| Activity |
IC50 = 56000 nM
|
[9] | |||
| Compound Name |
(S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldisulfanyl-propionylamino)-methyl]-3-benzyloxy-tetrahydro-pyran-2-carbonyl}-amino)-4-methyl-pentanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL189409; BDBM50150662
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| Activity |
IC50 = 57000 nM
|
[15] | |||
| Compound Name |
(S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}-benzoylamino)-4-methylsulfanyl-butyric acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL60780; SCHEMBL8367905; BDBM50079665; N-[3-[(4-Imidazolylmethyl)aminomethyl]benzoyl]-L-methionine; (2S)-2-[[3-[(1H-imidazol-5-ylmethylamino)methyl]benzoyl]amino]-4-methylsulfanylbutanoic acid
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| Activity |
IC50 = 57600 nM
|
[16] | |||
| Compound Name |
3-Benzoyl-5-methyl-N-prop-2-ynylindolizine-1-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361078; BDBM50036278
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|
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| Activity |
IC50 = 57800 nM
|
[17] | |||
| Compound Name |
(2S)-4-Methyl-2-[[2-naphthalen-1-yl-4-(pyridin-4-ylmethylamino)benzoyl]amino]pentanoic Acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL282814; SCHEMBL6781382; GGTI-2164; BDBM50076145; (S)-4-Methyl-2-{2-naphthalen-1-yl-4-[(pyridin-4-ylmethyl)-amino]-benzoylamino}-pentanoic acid
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| Activity |
IC50 = 58000 nM
|
[10] | |||
| Compound Name |
[1-(3H-Imidazol-4-ylmethyl)-7-phenyl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-(2-methoxy-naphthalen-1-yl)-methanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL358499; SCHEMBL3502129; BDBM50083408
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| Activity |
IC50 = 58000 nM
|
[18] | |||
| Compound Name |
Kurasoin A
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1233878; BDBM50492943; Q27462087
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| Activity |
IC50 = 59000 nM
|
[19] | |||
| Compound Name |
1-(1H-Indol-3-yl)-4-phenylbutane-2,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1233879; BDBM50492942; Q27462086
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|
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| Activity |
IC50 = 59000 nM
|
[19] | |||
| Compound Name |
2-[3-[5-[[[(2S)-1-[[(2S)-1-[[(1S)-1-Carboxy-3-methylsulfanylpropyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]methyl]-1-methylimidazol-2-yl]propyl]butanedioic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL590239; BDBM50481631; N-[2-(4,5-Dicarboxypentyl)-1-methyl-1H-imidazole-5-ylmethyl]-Val-Phe-Met-OH
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| Activity |
IC50 = 60000 nM
|
[20] | |||
| Compound Name |
3-[(3Ar,6R,9S)-3-(1,5-Dimethyl-hexyl)-9-ethyl-3a,6-dimethyl-7-oxo-dodecahydro-cyclopenta[a]naphthalen-6-yl]-propionic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL140345; BDBM50067820
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|
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| Activity |
IC50 = 60000 nM
|
[9] | |||
| Compound Name |
2-[[(4E,8E)-5,9,13-Trimethyltetradeca-4,8,12-trienoyl]amino]propanedioic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL598573; BDBM50481620
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|
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| Activity |
IC50 = 60000 nM
|
[20] | |||
| Compound Name |
(7E,11E)-8,12,16-Trimethyl-5-oxoheptadeca-7,11,15-trienoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL586003; BDBM50481629
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|
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| Activity |
IC50 = 60000 nM
|
[20] | |||
| Compound Name |
(8E,12E)-9,13,17-Trimethyl-5-oxooctadeca-8,12,16-trienoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL597132; BDBM50481626
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|
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| Activity |
IC50 = 60000 nM
|
[20] | |||
| Compound Name |
[(3Z)-4-[4-(Dimethylamino)pyridin-1-ium-1-yl]-2-ethoxycarbonyl-5-(4-fluorophenyl)-5-oxopenta-1,3-dienylidene]azanide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2435002; BDBM50493677
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|
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| Activity |
IC50 = 62300 nM
|
[13] | |||
| Compound Name |
[(3Z)-4-[4-(Dimethylamino)pyridin-1-ium-1-yl]-2-ethoxycarbonyl-5-(4-methoxyphenyl)-5-oxopenta-1,3-dienylidene]azanide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2435010; BDBM50493662
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|
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| Activity |
IC50 = 62670 nM
|
[13] | |||
| Compound Name |
(2S)-3-Hydroxy-2-[[(2S)-4-methyl-2-[[(2S)-3-methyl-2-[(2-phenylmethoxybenzoyl)amino]butanoyl]amino]pentanoyl]amino]propanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL55617; BDBM50450067
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|
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| Activity |
IC50 = 63000 nM
|
[21] | |||
| Compound Name |
(2R)-2-(3-Carbazol-9-ylpropanoylamino)-3-sulfanylpropanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623715; BDBM50498789
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|
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| Activity |
IC50 = 65400 nM
|
[22] | |||
| Compound Name |
(2S,3S)-2-Imidazol-1-ylmethyl-2,3,5,6,7,8-hexahydro-naphtho[2,3-b]thiophen-3-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL423705; BDBM50061493
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|
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| Activity |
IC50 ~ 70000 nM
|
[14] | |||
| Compound Name |
Methyl (2S)-2-[(2R)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-methylbutanamido]-3-(4-hydroxy-2,3-dimethylphenyl)propanamido]-4-(methylsulfanyl)butanoate
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|
Investigative | Compound Info | ||
| Synonyms |
Compound XV; CAAX Analogue 15; CHEMBL203879; BDBM13372
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|
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| Activity |
IC50 = 70500 nM
|
[23] | |||
| Compound Name |
3-Benzoyl-7-methylindolizine-1-carboxylic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3361072; BDBM50036271
Click to Show/Hide
|
||||
| Activity |
IC50 = 72300 nM
|
[17] | |||
| Compound Name |
5-Chloro-2-imidazol-1-ylmethyl-2,3-dihydro-benzo[b]thiophen-3-ol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL133918; SCHEMBL10816205; BDBM50061478
Click to Show/Hide
|
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| Activity |
IC50 ~ 75000 nM
|
[14] | |||
| Compound Name |
2-(Dimethylamino)ethyl 4-(4-azatricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaen-2-ylidene)piperidine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL130258; BDBM50061459
Click to Show/Hide
|
||||
| Activity |
IC50 = 79000 nM
|
[14] | |||
| Compound Name |
(S)-4-Methylsulfanyl-2-{3-[(4-nitro-benzylamino)-methyl]-benzoylamino}-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL60565; BDBM50079662
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[16] | |||
| Compound Name |
4-{[(4-Cyanophenyl)(1-methyl-1H-imidazol-5-yl)methoxy]methyl}-3-(3-methoxyphenyl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
A313326 Analogue 40; CHEMBL347942; BDBM13401
Click to Show/Hide
|
||||
| Activity |
IC50 = 83176.38 nM
|
[24] | |||
| Compound Name |
CID 46230685
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL598779; BDBM50481621; [(4E,8E)-5,9,13-trimethyltetradeca-4,8,12-trienoyl]sulfamic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 85000 nM
|
[20] | |||
| Compound Name |
(E)-4-[4-(Dimethylamino)pyridin-1-ium-1-yl]-5-oxo-5-phenothiazin-10-ylpent-2-enoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2312772; BDBM50489189
Click to Show/Hide
|
||||
| Activity |
IC50 = 86490 nM
|
[25] | |||
| Compound Name |
Methyl (2S)-2-[[(2S,3R)-3-methyl-2-[[(2S)-3-methyl-2-[[(2R)-2-(phenylmethoxycarbonylamino)-3-phenylmethoxycarbonylsulfanylpropanoyl]amino]butanoyl]amino]pentanoyl]amino]-4-methylsulfanylbutanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790705; BDBM50366347
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[26] | |||
| Compound Name |
1-[1-(3H-Imidazol-4-ylmethyl)-7-phenyl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-2-(4-methoxy-phenyl)-ethane-1,2-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL348452; SCHEMBL3501260; BDBM50083414
Click to Show/Hide
|
||||
| Activity |
IC50 = 91000 nM
|
[18] | |||
| Compound Name |
(2S)-2-[[(2S,3S,6S)-6-[[[(2R)-2-Amino-3-(tert-butyldisulfanyl)propanoyl]amino]methyl]-3-phenylmethoxyoxane-2-carbonyl]amino]-4-methylsulfinylbutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL365616; BDBM50150664
Click to Show/Hide
|
||||
| Activity |
IC50 = 91000 nM
|
[15] | |||
| Compound Name |
1-(1H-Imidazole-5-ylmethyl)-4-(1-naphthylcarbonyl)-7-phenyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL341861; SCHEMBL3499970; BDBM50083434
Click to Show/Hide
|
||||
| Activity |
IC50 = 95000 nM
|
[18] | |||
| Compound Name |
CID 44359346
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL139463; BDBM50067838
Click to Show/Hide
|
||||
| Activity |
IC50 = 96000 nM
|
[9] | |||
| Compound Name |
2-Methyl-2,3-dihydro-pyrazino[1,2-a]indole-1,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL420726; NSC175901; DTXSID50306367; BDBM50134313; NSC-175901; 2-Methyl-1,2,3,4-tetrahydropyrazino[1,2-a]indole-1,4-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
6-Hydroxy-8-methyl-3-[2-[(1S,6S)-2,2,6-trimethylcyclohexyl]ethyl]-2,5-dihydro-1-benzoxepine-9-carbaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683672; BDBM50483443
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
2-Ethyl-butyric acid 2-((10R,11S,13S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL139541; BDBM50067837
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
(S)-2-[((S)-2-{2-[Tert-Butoxycarbonyl-(2-mercapto-ethyl)-amino]-acetyl}-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl)-amino]-4-methylsulfanyl-butyric acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90676; BDBM50285839
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[28] | |||
| Compound Name |
(S)-4-Methyl-2-{2-naphthalen-1-yl-4-[(pyridin-2-ylmethyl)-amino]-benzoylamino}-pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL282297; GGTI-2145; BDBM50076136
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[10] | |||
| Compound Name |
1-[1-(4-Cyanobenzyl)-1H-imidazole-5-ylmethyl]-4-(3-chlorophenyl)piperazine-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL150449; L778123 analog; SCHEMBL3845494; BCP16388; BDBM50097081; AKOS030228068; KS-00000016
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[29] | |||
| Compound Name |
[(2S,10R,13R)-17-(1,5-Dimethyl-hexyl)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-2-yl]-acetic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL139097; BDBM50067822
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
3'-[[[(R)-2-Amino-3-mercaptopropionyl]amino]methyl]-1,1'-biphenyl-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL69076; SCHEMBL8111003; BDBM50048951; 3''-[((R)-2-Amino-3-mercapto-propionylamino)-methyl]-biphenyl-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[30] | |||
| Compound Name |
CID 44359605
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL141578; BDBM50067832
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
3-[(3Ar,6R,9S)-3-(1,5-Dimethyl-hexyl)-3a,6,9-trimethyl-7-oxo-dodecahydro-cyclopenta[a]naphthalen-6-yl]-propionic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL435821; BDBM50067840
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
2-(Benzoyl-piperidin-4-yl-amino)-4-methylsulfanyl-butyric acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL150314; BDBM50108786; (S)-2-[N-(4-Piperidinyl)benzoylamino]-4-(methylthio)butyric acid methyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
2,4-Dihydroxy-3-[2-hydroxy-3-methyl-5-[(1S,6S)-2,2,6-trimethylcyclohexyl]pentyl]-6-methylbenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683670; BDBM50483445
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
(10R,13S)-17-(2-Hydroxy-acetyl)-10,13-dimethyl-1,6,7,8,9,10,12,13,14,15,16,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,11-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL138700; 11-DEHYDROCORTICOSTERONE; BDBM50067839
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
2,4-Dihydroxy-6-methyl-3-[3-methylidene-2-oxo-5-[(1S,6S)-2,2,6-trimethylcyclohexyl]pentyl]benzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683671; BDBM50483437
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
2-Methyl-2,3,10,10a-tetrahydro-pyrazino[1,2-a]indole-1,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL332434; NSC175898; BDBM50134309; NSC-175898; 2-methyl-1H,2H,3H,4H,10H,10aH-pyrazino[1,2-a]indole-1,4-dione; 2-Methyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indole-1,4-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(S)-2-{3-[((R)-2-Acetylamino-3-mercapto-propionylamino)-methyl]-benzoylamino}-4-methylsulfanyl-butyric acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL87349; BDBM50283542
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[26] | |||
| Compound Name |
(2S)-2-[[(3S)-2-[2-[2-[2-[[2-[(3S)-3-[[(1S)-1-Carboxy-3-methylsulfanylpropyl]carbamoyl]-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-[(2-methylpropan-2-yl)oxycarbonyl]amino]ethyldisulfanyl]ethyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetyl]-3,4-dihydro-1H-isoquinoline-3-carbonyl]amino]-4-methylsulfanylbutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL262383; BDBM50285841
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[28] | |||
| Compound Name |
CID 11603180
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683666; BDBM50483434; 2,4-dihydroxy-3-[(6E)-2-hydroxy-7,11-dimethyl-3-methylidenedodeca-6,10-dienyl]-6-methylbenzaldehyde
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
(7S,10R,13R)-17-(1,5-Dimethyl-hexyl)-7-ethyl-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL138567; BDBM50067845
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
Methyl (2S)-2-[benzoyl-[1-[(4S)-1,3-thiazolidine-4-carbonyl]piperidin-4-yl]amino]-4-methylsulfanylbutanoate;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2093927
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
2,4-Dihydroxy-3-[2-hydroxy-3-methylidene-5-[(1S,6S)-2,2,6-trimethylcyclohexyl]pentyl]-6-methylbenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683664; BDBM50483441
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
(S)-2-[((S)-2-{2-[Tert-Butoxycarbonyl-(2-mercapto-ethyl)-amino]-acetyl}-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl)-amino]-4-methylsulfanyl-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328068; BDBM50285843
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[28] | |||
| Compound Name |
(2S)-2-[(2R)-3-(4-Hydroxy-2,3-dimethylphenyl)-2-[(2S)-2-[(2R)-2-formamido-3-sulfanylpropanamido]-3-methylbutanamido]propanamido]-4-(methylsulfanyl)butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Cmpound XI; CAAX Analogue 11; CHEMBL381525; BDBM13368
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
CID 11710728
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683669; BDBM50483436; 3-[5-(1-adamantyl)-2-hydroxy-3-methylidenepentyl]-2,4-dihydroxy-6-methylbenzaldehyde
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
3-Benzyldisulfanyl-2-methyl-2,3-dihydro-pyrazino[1,2-a]indole-1,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL121090; BDBM50134308; 2-Methyl-3-(benzyldithio)-1,2,3,4-tetrahydropyrazino[1,2-a]indole-1,4-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
3-(5-Cyclohexyl-2-hydroxy-3-methylidenepentyl)-2,4-dihydroxy-6-methylbenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683665; BDBM50483433
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
CID 11501268
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683668; BDBM50483442; 3-[5-(2,6-dimethylphenyl)-2-hydroxy-3-methylidenepentyl]-2,4-dihydroxy-6-methylbenzaldehyde
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
9-Methoxy-2-methyl-2,3-dihydro-pyrazino[1,2-a]indole-1,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL121296; BDBM50134314; 2-Methyl-9-methoxy-1,2,3,4-tetrahydropyrazino[1,2-a]indole-1,4-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(S)-2-[(3Ar,6R)-3-(1,5-Dimethyl-hexyl)-3a,6-dimethyl-7-oxo-dodecahydro-cyclopenta[a]naphthalen-6-ylmethyl]-succinic acid 4-ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL141093; BDBM50067836
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
3-((3As,6R)-3-Acetyl-3a,6-dimethyl-5,7-dioxo-dodecahydro-cyclopenta[a]naphthalen-6-yl)-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL335152; BDBM50067824
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
2-[2-Hydroxy-3-methylidene-5-[(1S,6S)-2,2,6-trimethylcyclohexyl]pentyl]-5-methylbenzene-1,3-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683675; BDBM50483444
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
Ethyl 3-(4-chlorophenyl)-4-cyano-5-[[2-(1H-imidazol-5-yl)acetyl]amino]thiophene-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3764435; BDBM50139639
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[31] | |||
| Compound Name |
9-Methoxy-2-methyl-2,3,10,10a-tetrahydro-pyrazino[1,2-a]indole-1,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL333703; BDBM50134310; 2-Methyl-9-methoxy-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indole-1,4-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
CID 23633300
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683674; BDBM50483439
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
(S)-2-{3-[((R)-2-Benzyloxycarbonylamino-3-benzyloxycarbonylsulfanyl-propionylamino)-methyl]-benzoylamino}-4-methylsulfanyl-butyric acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL85575; BDBM50283539
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[26] | |||
| Compound Name |
[(2S,10R,13R)-17-(1,5-Dimethyl-hexyl)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-2-yl]-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL424292; BDBM50067850
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
3-Benzyldisulfanyl-9-methoxy-2-methyl-2,3-dihydro-pyrazino[1,2-a]indole-1,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL119548; BDBM50134311; 2-Methyl-9-methoxy-3-(benzyldithio)-1,2,3,4-tetrahydropyrazino[1,2-a]indole-1,4-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
CID 44359351
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL138142; BDBM50067829
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
2,4-Dihydroxy-3-(2-hydroxy-3-methylbut-3-enyl)-6-methylbenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683667; BDBM50483435
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
2-Hydroxy-3-[2-hydroxy-3-methylidene-5-[(1S,6S)-2,2,6-trimethylcyclohexyl]pentyl]-4-methoxy-6-methylbenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1683673; BDBM50483438
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
Methyl (2S)-2-[[(3S)-2-[2-[2-[2-[[2-[(3S)-3-[[(2S)-1-methoxy-4-methylsulfanyl-1-oxobutan-2-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-[(2-methylpropan-2-yl)oxycarbonyl]amino]ethyldisulfanyl]ethyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetyl]-3,4-dihydro-1H-isoquinoline-3-carbonyl]amino]-4-methylsulfanylbutanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL412576; BDBM50285840
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[28] | |||
| Compound Name |
3-[(E,E)-3,7,11-Trimethyl-2,6,10-dodecatrienylamino]-3-oxo-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL95303; SCHEMBL6056482; SCHEMBL7621768; BDBM50453725; 3-Oxo-3-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]amino]propionic acid; 3-oxo-3-[[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]amino]propanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 115000 nM
|
[12] | |||
| Compound Name |
[2-(2-Hydroxy-ethylsulfanyl)-phenyl]-[1-(3H-imidazol-4-ylmethyl)-7-phenyl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148870; SCHEMBL3498453; BDBM50083429
Click to Show/Hide
|
||||
| Activity |
IC50 = 124000 nM
|
[18] | |||
| Compound Name |
4-Oxo-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienoxy]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL597740; SCHEMBL15851471; BDBM50481630
Click to Show/Hide
|
||||
| Activity |
IC50 = 130000 nM
|
[20] | |||
| Compound Name |
(2E,5E,9E)-6,10,14-Trimethylpentadeca-2,5,9,13-tetraenoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL597738; SCHEMBL16167488; SCHEMBL16428262; BDBM50481627
Click to Show/Hide
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||||
| Activity |
IC50 = 130000 nM
|
[20] | |||
| Compound Name |
(2S)-3-Hydroxy-2-[[(2S)-2-[[(2S)-2-[(5-hydroxy-2-phenylmethoxybenzoyl)amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL417232; BDBM50450071
Click to Show/Hide
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||||
| Activity |
IC50 = 137000 nM
|
[21] | |||
| Compound Name |
[1-(3H-Imidazol-4-ylmethyl)-7-pyridin-3-yl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL359092; SCHEMBL3502056; BDBM50083413
Click to Show/Hide
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||||
| Activity |
IC50 = 145000 nM
|
[18] | |||
| Compound Name |
(2S)-3-Hydroxy-2-[[(2S)-2-[[(2S)-2-[(3-hydroxy-2-phenylmethoxybenzoyl)amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]propanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL57693; BDBM50450073
Click to Show/Hide
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||||
| Activity |
IC50 = 157000 nM
|
[21] | |||
| Compound Name |
Malonic acid 1-(3,7,11-trimethyl-2,6,10-dodecatrienyl) ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL585242; SCHEMBL17251244; BDBM50481624
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||||
| Activity |
IC50 = 160000 nM
|
[20] | |||
| Compound Name |
(2S)-3-Hydroxy-2-[[(2S)-4-methyl-2-[[(2S)-3-methyl-2-[(4-phenylmethoxybenzoyl)amino]butanoyl]amino]pentanoyl]amino]propanoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL299507; BDBM50450064
Click to Show/Hide
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||||
| Activity |
IC50 = 166000 nM
|
[21] | |||
| Compound Name |
N-[1-(3H-Imidazol-4-ylmethyl)-4-(naphthalene-1-carbonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-8-yl]-acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL149103; SCHEMBL3501593; BDBM50083427
Click to Show/Hide
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||||
| Activity |
IC50 = 168000 nM
|
[18] | |||
| Compound Name |
(5E,9E)-6,10,14-Trimethylpentadeca-5,9,13-trienoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL597739; BDBM50481622
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||||
| Activity |
IC50 = 170000 nM
|
[20] | |||
| Compound Name |
[1-(3H-Imidazol-4-ylmethyl)-7-pyridin-2-yl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL348237; SCHEMBL3500156; BDBM50083440
Click to Show/Hide
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||||
| Activity |
IC50 = 177000 nM
|
[18] | |||
| Compound Name |
[7-Cyclohexyl-1-(3H-imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL348262; SCHEMBL3500164; BDBM50083436
Click to Show/Hide
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||||
| Activity |
IC50 = 186000 nM
|
[18] | |||
| Compound Name |
5-((E)-4,8-Dimethyl-nona-3,7-dienyl)-3a,4,7,7a-tetrahydro-isobenzofuran-1,3-dione
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL82796; BDBM50108509; 5-[(3E)-4,8-Dimethyl-3,7-nonadienyl]-1,3,3a,4,7,7a-hexahydroisobenzofuran-1,3-dione
Click to Show/Hide
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||||
| Activity |
IC50 = 190000 nM
|
[32] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 53 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Ethylene diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
ethylenediamine; Ethane-1,2-diamine; 1,2-Ethanediamine; 107-15-3; 1,2-Diaminoethane; Ethylene diamine; Ethylendiamine; Dimethylenediamine; edamine; 1,2-Ethylenediamine; Aethaldiamin; Ethyleendiamine; Aethylenediamin; Ethylene-diamine; beta-Aminoethylamine; 1,2-Diaminoaethan; Amerstat 274; Algicode 106L; 1,2-Diamino-ethano; 1,2-Diamino-ethaan; Aethaldiamin [German]; Caswell No. 437; Ethylenediamine [JAN]; Ethyleendiamine [Dutch]; 1,2-Ethanediamine, homopolymer; Aethylenediamin [German]; Ethylene-diamine [French]; NCI-C60402
Click to Show/Hide
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||||
| Activity |
IC50 = 15500000 nM
|
[33] | |||
| Compound Name |
CID 46230630
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL609900; BDBM50481628; (7E,11E)-8,12,16-Trimethyl-4-oxoheptadeca-7,11,15-trienoic acid
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[20] | |||
| Compound Name |
(4E,8E)-5,9,13-Trimethyltetradeca-4,8,12-trienamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL598777; SCHEMBL7617406; BDBM50481623
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[20] | |||
| Compound Name |
(4E,8E)-N-(Benzenesulfonyl)-5,9,13-trimethyltetradeca-4,8,12-trienamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL589907; BDBM50481614
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||||
| Activity |
IC50 > 200000 nM
|
[20] | |||
| Compound Name |
(3,4-Dihydro-2H-quinolin-1-yl)-[1-(3H-imidazol-4-ylmethyl)-7-phenyl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL149160; SCHEMBL3501039; BDBM50083423
Click to Show/Hide
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||||
| Activity |
IC50 = 205000 nM
|
[18] | |||
| Compound Name |
4-Oxo-4-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]amino]butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97933; SCHEMBL8940669; BDBM50453716
Click to Show/Hide
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||||
| Activity |
IC50 = 220000 nM
|
[12] | |||
| Compound Name |
7-Bromo-4-(1-naphthylcarbonyl)-1-(1H-imidazole-5-ylmethyl)-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL121010; SCHEMBL3501162; BDBM50083431; [7-bromo-1-(1H-imidazol-5-ylmethyl)-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-naphthalen-1-ylmethanone
Click to Show/Hide
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||||
| Activity |
IC50 = 228000 nM
|
[18] | |||
| Compound Name |
N-[1-(3H-Imidazol-4-ylmethyl)-4-(naphthalene-1-carbonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-8-yl]-benzenesulfonamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL151633; SCHEMBL3502266; BDBM50083416
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|
||||
| Activity |
IC50 = 249000 nM
|
[18] | |||
| Compound Name |
1-(3-Chlorophenyl)-4-[1-(4-cyanobenzyl)-1H-imidazole-5-ylmethyl]piperazine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL150389; BDBM50097079; 4-{5-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-imidazol-1-ylmethyl}-benzonitrile
Click to Show/Hide
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||||
| Activity |
IC50 = 250000 nM
|
[29] | |||
| Compound Name |
(2R,3R)-2-Imidazol-1-ylmethyl-4-methyl-2,3-dihydro-benzo[b]thiophen-3-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL334598; BDBM50061423; (2R,3R)-2-((1H-imidazol-1-yl)methyl)-4-methyl-2,3-dihydrobenzo[b]thiophen-3-ol
Click to Show/Hide
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||||
| Activity |
IC50 = 266000 nM
|
[14] | |||
| Compound Name |
(S)-2-({(2S,3S,6S)-6-[((R)-2-Amino-3-tert-butyldisulfanyl-propionylamino)-methyl]-3-benzyloxy-tetrahydro-pyran-2-carbonyl}-amino)-4-methyl-pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL187467; BDBM50150663
Click to Show/Hide
|
||||
| Activity |
IC50 = 321000 nM
|
[15] | |||
| Compound Name |
Tetrasodium;[2-[1-[[(2R,3S)-3-methyl-3-(4-methylpent-3-enyl)oxiran-2-yl]methyl]triazol-4-yl]-1-phosphonatoethyl]-dioxido-oxo-lambda5-phosphane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3262354; BDBM50013159
Click to Show/Hide
|
||||
| Activity |
IC50 = 340000 nM
|
[34] | |||
| Compound Name |
[1-(3H-Imidazol-4-ylmethyl)-9-methyl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL151978; SCHEMBL3500795; BDBM50083441
Click to Show/Hide
|
||||
| Activity |
IC50 = 350000 nM
|
[18] | |||
| Compound Name |
(2S)-3-Hydroxy-2-[[(2S)-4-methyl-2-[[(2S)-3-methyl-2-[[(2S)-4-[methyl(phenylmethoxy)amino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxobutanoyl]amino]butanoyl]amino]pentanoyl]amino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL334415; BDBM50454415
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||||
| Activity |
IC50 > 360000 nM
|
[35] | |||
| Compound Name |
(2S)-3-Hydroxy-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-[hydroxy(methyl)amino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxobutanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL134839; BDBM50454417
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|
||||
| Activity |
IC50 > 360000 nM
|
[35] | |||
| Compound Name |
(2S)-3-Hydroxy-2-[[(2S)-4-methyl-2-[[(2S)-3-methyl-2-[(3-phenylmethoxybenzoyl)amino]butanoyl]amino]pentanoyl]amino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL59579; BDBM50450062
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||||
| Activity |
IC50 > 360000 nM
|
[21] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-4-[hydroxy(methyl)amino]-4-oxobutanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL133888; BDBM50454418
Click to Show/Hide
|
||||
| Activity |
IC50 > 360000 nM
|
[35] | |||
| Compound Name |
(E)-2-(2-{(S)-1-[(S)-1-((S)-1-Carboxy-2-hydroxy-ethylcarbamoyl)-3-methyl-butylcarbamoyl]-2-methyl-propylcarbamoyl}-ethyl)-5,9,13-trimethyl-tetradeca-4,8,12-trienoic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL63798; BDBM50283065
Click to Show/Hide
|
||||
| Activity |
IC50 > 360000 nM
|
[36] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-hydroxypropanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL59525; BDBM50450066
Click to Show/Hide
|
||||
| Activity |
IC50 > 360000 nM
|
[21] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-4-[methyl(phenylmethoxy)amino]-4-oxobutanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL334944; BDBM50454413
Click to Show/Hide
|
||||
| Activity |
IC50 > 360000 nM
|
[35] | |||
| Compound Name |
(2S)-3-Hydroxy-2-[[(2S)-2-[[(2S)-2-[(2-hydroxy-3-phenylmethoxybenzoyl)amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL57276; BDBM50450065
Click to Show/Hide
|
||||
| Activity |
IC50 > 360000 nM
|
[21] | |||
| Compound Name |
(2S)-3-Hydroxy-2-[[(2S)-2-[[(2S)-2-[(4-hydroxybenzoyl)amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL301694; BDBM50450072
Click to Show/Hide
|
||||
| Activity |
IC50 > 360000 nM
|
[21] | |||
| Compound Name |
(2S)-3-Hydroxy-2-[[(2S)-2-[[(2S)-2-[(2-hydroxybenzoyl)amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL57247; BDBM50450068
Click to Show/Hide
|
||||
| Activity |
IC50 > 360000 nM
|
[21] | |||
| Compound Name |
(S)-3-Hydroxy-2-{(S)-4-methyl-2-[(S)-3-methyl-2-((10E,14E)-7,11,15-trimethyl-hexadeca-6,10,14-trienoylamino)-butyrylamino]-pentanoylamino}-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL63339; BDBM50283067
Click to Show/Hide
|
||||
| Activity |
IC50 > 360000 nM
|
[36] | |||
| Compound Name |
Tetrasodium;[2-[1-[(2Z)-3,7-dimethylocta-2,6-dienyl]triazol-4-yl]-1-phosphonatoethyl]-dioxido-oxo-lambda5-phosphane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3262352; BDBM50013157
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[34] | |||
| Compound Name |
Tetrasodium;[2-[1-[[(2R,3R)-3-methyl-3-(4-methylpent-3-enyl)oxiran-2-yl]methyl]triazol-4-yl]-1-phosphonatoethyl]-dioxido-oxo-lambda5-phosphane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3262353; BDBM50013158
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[34] | |||
| Compound Name |
Dodec-2-enylsuccinic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL441996; EINECS 237-640-7; 2-[(E)-dodec-2-enyl]butanedioic acid; (2-Dodecenyl)succinic acid; 2-Dodec-2-enyl-succinic acid; BDBM50108514
Click to Show/Hide
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||||
| Activity |
IC50 = 402000 nM
|
[32] | |||
| Compound Name |
1-(3H-Imidazol-4-ylmethyl)-4-(naphthalene-1-sulfonyl)-7-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL151362; SCHEMBL3499752; BDBM50083446; 1-(1H-imidazol-5-ylmethyl)-4-naphthalen-1-ylsulfonyl-7-phenyl-3,5-dihydro-2H-1,4-benzodiazepine
Click to Show/Hide
|
||||
| Activity |
IC50 = 426000 nM
|
[18] | |||
| Compound Name |
1,3-Isobenzofurandione, 3a,4,7,7a-tetrahydro-5-(4-methyl-3-pentenyl)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1,2,3,6-Tetrahydro-4-(4-methylpent-3-enyl)phthalic anhydride; CHEMBL85858; 1,3-Isobenzofurandione, 3a,4,7,7a-tetrahydro-5-(4-methyl-3-penten-1-yl)-; 5-(4-methylpent-3-en-1-yl)-3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione; EINECS 249-870-5; 1,3-Isobenzofurandione, 3a,4,7,7a-hexahydro-5-(4-methyl-3-pentenyl)-; SCHEMBL11627085; CTK4G3848; DTXSID80865513; BBL028845; BDBM50108511; STK801817; 5-(4-methylpent-3-en-1-yl)-3a,4,7,7a-tetrahydroisobenzofuran-1,3-dione; 5-(4-methylpent-3-enyl)-3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione; AKOS015955701; MCULE-5816353779; VS-08993; 1,2,3,6-tetrahydro-4-(4-methyl-3-pentenyl)phthalic anhydride; 4-(4-Methyl-3-pentenyl)-4-cyclohexene-1,2-dicarboxylic anhydride; 1,3-Isobenzofurandione,3a,4,7,7a-tetrahydro-5-(4-methyl-3-penten-1-yl)-; 5-(4-Methyl-pent-3-enyl)-3a,4,7,7a-tetrahydro-isobenzofuran-1,3-dione; 5-(4-methylpent-3-en-1-yl)-1,3,3a,4,7,7a-hexahydro-2-benzofuran-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 449000 nM
|
[32] | |||
| Compound Name |
[(3S,4Ar,6aS,12aR,12bS)-11-hydroxy-8,9-bis(hydroxymethyl)-4,4,6a,12b-tetramethyl-1,2,3,4a,5,6,12,12a-octahydrobenzo[a]xanthen-3-yl] acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL292063; BDBM50071240
Click to Show/Hide
|
||||
| Activity |
IC50 = 460000 nM
|
[37] | |||
| Compound Name |
Tetrasodium;[2-[1-(3,7-dimethylocta-2,6-dienyl)triazol-4-yl]-1-phosphonatoethyl]-dioxido-oxo-lambda5-phosphane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2315880
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[34] | |||
| Compound Name |
Tetrasodium;[2-[1-[(2E)-3,7-dimethylocta-2,6-dienyl]triazol-4-yl]-1-phosphonatoethyl]-dioxido-oxo-lambda5-phosphane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3262351; BDBM50013156
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[34] | |||
| Compound Name |
[8-Chloro-1-(3H-imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL150690; SCHEMBL3499785; BDBM50083421
Click to Show/Hide
|
||||
| Activity |
IC50 = 540000 nM
|
[18] | |||
| Compound Name |
Acetic acid (3S,4aR,6aS,12aR,12bS)-8,9-diformyl-11-hydroxy-4,4,6a,12b-tetramethyl-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-2H-benzo[a]xanthen-3-yl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL66466; Kampanol C; BDBM50071239
Click to Show/Hide
|
||||
| Activity |
IC50 = 560000 nM
|
[37] | |||
| Compound Name |
2-[[4-(Dimethylamino)-6-[(2-sulfanylethylamino)methyl]-2-pyridyl]methylamino]ethanethiol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL36582; NSC688138; CTK8C9935; ZINC5579139; BDBM50127226; 4-(Dimethylamino)-2,6-bis[[(2-mercaptoethyl)amino]methy]pyridine; 2,2'-{[4-(dimethylamino)pyridine-2,6-diyl]bis(methanediylimino)}diethanethiol; 2-({4-Dimethylamino-6-[(2-mercapto-ethylamino)-methyl]-pyridin-2-ylmethyl}-amino)-ethanethiol
Click to Show/Hide
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||||
| Activity |
IC50 = 620000 nM
|
[33] | |||
| Compound Name |
1-(3H-Imidazol-4-ylmethyl)-7-phenyl-4-(1-phenyl-1H-tetrazol-5-yl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL357714; SCHEMBL3499604; BDBM50083424; 1-(1H-imidazol-5-ylmethyl)-7-phenyl-4-(1-phenyltetrazol-5-yl)-3,5-dihydro-2H-1,4-benzodiazepine
Click to Show/Hide
|
||||
| Activity |
IC50 = 702000 nM
|
[18] | |||
| Compound Name |
11-(1-Methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[1,2]cyclohepta[3,4-b]pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL134232; SCHEMBL8878333; BDBM50061451; 11-(1-Methyl-piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Click to Show/Hide
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||||
| Activity |
IC50 = 724000 nM
|
[14] | |||
| Compound Name |
2-Methyl-3-(acetylthio)-9-methoxy-1,2,3,4-tetrahydropyrazino[1,2-a]indole-1,4-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL120863; BDBM50134312; Thioacetic acid S-(9-methoxy-2-methyl-1,4-dioxo-1,2,3,4-tetrahydro-pyrazino[1,2-a]indol-3-yl) ester
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| Activity |
IC50 = 748000 nM
|
[3] | |||
| Compound Name |
Lauric anhydride
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Investigative | Compound Info | ||
| Synonyms |
Dodecanoic anhydride; dodecanoyl dodecanoate; Lauroyl anhydride; Dodecanoic acid, anhydride; n-dodecanoic anhydride; CHEMBL420797; MFCD00008965; Lauricanhydride; dodecanoyl anhydride; EINECS 211-449-9; lauric acid anhydride; Dodecanoic anhydride #; dodecanoic acid anhydride; ACMC-1B2U7; Dodecanoic anhydride >=98%; SCHEMBL468394; Dodecanoic anhydride, >=98%; Dodecanoic acid,1,1'-anhydride; CTK5C1410; DTXSID10214752; ANW-34911; BDBM50108507; NSC293871; ZINC44201930; AKOS015950639; NSC-293871; AS-56747; DB-054691; FT-0627722; L0017
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||||
| Activity |
IC50 = 854000 nM
|
[32] | |||
| Compound Name |
1-Phenyl-4-[1-(4-cyanobenzyl)-1H-imidazole-5-ylmethyl]piperazine-2,5-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL422861; BDBM50097077; 4-[5-(2,5-Dioxo-4-phenyl-piperazin-1-ylmethyl)-imidazol-1-ylmethyl]-benzonitrile
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||||
| Activity |
IC50 = 950000 nM
|
[29] | |||
| Compound Name |
4-(4-Methylpent-3-enyl)cyclohex-4-ene-1,2-dicarboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL314415; 4-Cyclohexene-1,2-dicarboxylic acid, 4-(4-methyl-3-pentenyl)-; ACMC-20mb7f; Oprea1_724370; CTK0D6485; DTXSID70396149; BDBM50108515; STL560987; AKOS030487675; 4-(4-Methyl-3-pentenyl)-4-cyclohexene-1,2-dicarboxylic acid; 4-(4-Methyl-pent-3-enyl)-cyclohex-4-ene-1,2-dicarboxylic acid; 4-(4-METHYLPENT-3-EN-1-YL)CYCLOHEX-4-ENE-1,2-DICARBOXYLIC ACID
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||||
| Activity |
IC50 > 1000000 nM
|
[32] | |||
| Compound Name |
4-(4,8,12-Trimethyltridecyl)-4-cyclohexene-1,2-dicarboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL87962; BDBM50108506; 4-(4,8,12-Trimethyl-tridecyl)-cyclohex-4-ene-1,2-dicarboxylic acid
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||||
| Activity |
IC50 > 1000000 nM
|
[32] | |||
| Compound Name |
(4E)-4-[(2E)-3,7-Dimethylocta-2,6-dienylidene]cyclohexane-1,2-dicarboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL314134; BDBM50108505; 4-[(E)-3,7-Dimethyl-octa-2,6-dien-(E)-ylidene]-cyclohexane-1,2-dicarboxylic acid
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||||
| Activity |
IC50 > 1000000 nM
|
[32] | |||
| Compound Name |
[8-Amino-1-(3H-imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL150737; SCHEMBL3502917; BDBM50083437; [8-amino-1-(1H-imidazol-5-ylmethyl)-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-naphthalen-1-ylmethanone
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||||
| Activity |
IC50 = 1000000 nM
|
[18] | |||
| Compound Name |
Itaconic anhydride
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Investigative | Compound Info | ||
| Synonyms |
3-methylideneoxolane-2,5-dione; Itaconic acid anhydride; Methylenesuccinic anhydride; 2,5-Furandione, dihydro-3-methylene-; 2-Methylenesuccinic anhydride; Dihydro-3-methylene-2,5-furandione; 3-methylenedihydrofuran-2,5-dione; Succinic anhydride, methylene-; MFCD00005530; UNII-Y455KS1U7Q; CHEMBL87967; Y455KS1U7Q; 3-Methylene-dihydro-furan-2,5-dione; Itaconic anhydride, 98%; Itaconicanhydride; 3-Methylenedihydro-2,5-furandione; 3,4-Dihydro-3-methylene-2,5-furandione; Itaconic anhydride, 95%; 2, dihydro-3-methylene-; SCHEMBL25233; 3-methyleneoxolane-2,5-dione; ACMC-2097a0; DTXSID8062230; CTK4E7519; KS-00000UUA; EBD1903; NSC43972; NSC43979; ZINC8100879; EINECS 218-518-2; ANW-13702; BDBM50108508; NSC 43979; NSC-43972; NSC-43979; 2,5-Furandione,dihydro-3-methylene-; 3-Methylenedihydro-2,5-furandione #; 3-methylenetetrahydrofuran-2,5-dione; AKOS015900399; GS-3259; NE10405; 3-methylene-tetrahydro-furan-2,5-dione; SC-18784; SY009111; DB-045673; FT-0627544; I0203; A20230; A815618; W-107530; Q15726050; F0001-0774; 2-(5-CHLORO-BENZOTRIAZOL-2-YL)-4-METHYL-6-(2-METHYL-ALLYL)-PHENOL
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||||
| Activity |
IC50 > 1000000 nM
|
[32] | |||
| Compound Name |
[2-Hydroxy-3-sulfanyl-1-(sulfanylmethyl)propyl] 2-(2,3-dihydro-1,4-benzodioxin-3-yl)thiazole-4-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL156166; BDBM50109933
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| Activity |
IC50 > 1000000 nM
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[38] | |||
| Compound Name |
5-(4,8,12-Trimethyl-tridecyl)-3a,4,7,7a-tetrahydro-isobenzofuran-1,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL86535; BDBM50108512; 5-(4,8,12-Trimethyltridecyl)-1,3,3a,4,7,7a-hexahydroisobenzofuran-1,3-dione
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| Activity |
IC50 > 1000000 nM
|
[32] | |||
| Compound Name |
2-Dodecen-1-ylsuccinic anhydride
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Investigative | Compound Info | ||
| Synonyms |
(2-Dodecenyl)succinic anhydride; 2-Dodecen-1-yl succinic anhydride; 2,5-Furandione, 3-(2-dodecenyl)dihydro-; 2,5-Furandione, 3-(2-dodecen-1-yl)dihydro-; CHEMBL87310; 3-[(E)-dodec-2-enyl]oxolane-2,5-dione; 2,5-Furandione, 3-dodecenyl-; MFCD00005528; 2-Dodecen-1-yl(-)succinic anhydride; DSSTox_CID_5217; 3-(Dodec-2-en-1-yl)dihydrofuran-2,5-dione; DSSTox_RID_77704; 2-Dodecenylsuccinic anhydride; DSSTox_GSID_25217; (2E)-3-(2-dodecen-1-yl)dihydro-2,5-furandione; Dihydro-3-(tetrapropenyl)furan-2,5-dione; ((E)-2-Dodecenyl)succinic anhydride; [(E)-2-Dodecenyl]succinic anhydride; 3-(2-Dodecenyl)succinic anhydride; n-Dodecenyl succinic anhydride (n-DDSA); CCRIS 4810; EINECS 243-296-9; EC 243-296-9; (2-Dodecen-1-yl)succinic; N-Dodecenyl succinic anhydride; 2-dodecen-1-yl-succinic anhydride; 2-(2-Dodecenyl)succinic anhydride; Tox21_202473; Tox21_303400; 6354AF; BDBM50108510; trans-(2-Dodecenyl)succinic anhydride; AKOS015903207; Epoxy embedding medium, hardener DDSA; CS-W010116; NCGC00091241-01; NCGC00091241-02; NCGC00257398-01; NCGC00260022-01; J149.584D; D0976; 2,5-Furandione, 3-(2E)-2-dodecenyldihydro-; ((E)-3-Dodec-2-enyl)-dihydro-furan-2,5-dione; (E)-3-(Dodec-2-en-1-yl)dihydrofuran-2,5-dione; 3-[(2E)-2-Dodecenyl]dihydro-2,5-furandione #; W-107677; W-110665; 3-(2-Dodecen-1-yl)dihydro-2,5-furandione, (2E)-; Q27288708; 2-Dodecen-1-ylsuccinic anhydride (cis- and trans- mixture); UNII-U3Z29QTW3P component UYCICMIUKYEYEU-ZHACJKMWSA-N
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| Activity |
IC50 > 1000000 nM
|
[32] | |||
| Compound Name |
(4-Chloro-phenylamino)-[1-(3H-imidazol-4-ylmethyl)-7-phenyl-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-methyl-cyanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL148811; SCHEMBL3502947; BDBM50083443
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| Activity |
IC50 = 1423000 nM
|
[18] | |||
| Compound Name |
2-[1-[(1-Oxidopyridin-1-ium-4-yl)methyl]piperidin-4-ylidene]-4-azatricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaene
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL434800; BDBM50061471
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||||
| Activity |
IC50 = 1832000 nM
|
[14] | |||
| Compound Name |
1-(3H-Imidazol-4-ylmethyl)-4-naphthalen-1-ylmethyl-7-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL356257; SCHEMBL3499870; BDBM50083432; 1-(1H-imidazol-5-ylmethyl)-4-(naphthalen-1-ylmethyl)-7-phenyl-3,5-dihydro-2H-1,4-benzodiazepine
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||||
| Activity |
IC50 = 2968000 nM
|
[18] | |||
| Compound Name |
1,10-Phenanthroline
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Investigative | Compound Info | ||
| Synonyms |
o-phenanthroline; Phenanthroline; orthophenanthroline; 4,5-diazaphenanthrene; 1,10-o-phenanthroline; 2-phenanthroline; 1,10-Phenanthroline anhydrous; [1,10]phenanthroline; beta-phenanthroline; 1,10-Fenanthrolin; .beta.-Phenanthroline; 1,10-Phenanthroline, Anhydrous; MFCD00011678; UNII-W4X6ZO7939; MLS000069797; CHEMBL415879; NSC 4265; W4X6ZO7939; NSC203545; NSC4265; SMR000058190; DSSTox_CID_5857; pyridino[3,2-h]quinoline; DSSTox_RID_77950; DSSTox_GSID_25857; 1,10-Phenanthroline, 99+%; MLS002701886; 1,10-Fenanthrolin [Czech]; Activ-8; NSC-4265; CCRIS 4855; EINECS 200-629-2; NSC 203545; phenantroline; o-Phenanthrolin; Cyto5A5; 1,10-phenanthrolin; 1,10-phenantroline; 1,10-phenathroline; 1,10 phenanthroline; 1,10-Fenanthroline; 1.10-phenanthroline; 1,1 0-phenanthroline; ACMC-209nwd; Opera_ID_711; [1,10]-Phenanthroline; Lopac-P-9375; Activ-8 in hexylene glycol; cid_1318; SCHEMBL8312; NCIStruc1_000192; NCIStruc2_000199; Lopac0_000985; KSC241K8T; ARONIS014409; DTXSID1025857; WLN: T B666 CN NNJ; 1,10 CPhenanthroline anhydrous; NCI4265; 1,10-Phenanthroline (anhydrous); 1,10-Phenanthroline, >=99%; 1,10-Phenanthroline,hydrochloride; HMS2234D03; HMS3263E11; HMS3371F11; ZINC164363; KS-000044UM; Tox21_201998; Tox21_303111; Tox21_500985; ANW-35243; BDBM50092158; CCG-38059; NCGC00013043; s6830; SBB089685; STL069281; AKOS000281773; CS-W004544; DB02365; HY-W004544; LP00985; MCULE-2911225521; NSC-203545; SDCCGSBI-0050958.P003; NCGC00013043-02; NCGC00013043-03; NCGC00013043-04; NCGC00013043-05; NCGC00013043-06; NCGC00013043-07; NCGC00013043-08; NCGC00013043-09; NCGC00013043-10; NCGC00013043-13; NCGC00091201-01; NCGC00091201-02; NCGC00091201-03; NCGC00091201-04; NCGC00257123-01; NCGC00259547-01; NCGC00261670-01; AC-18353; AK-27000; AS-14043; BR-27000; NCI60_003976; SC-23392; DB-013750; EU-0100985; FT-0606035; FT-0660636; P0221; P0879; P1826; ST45051101; Solution forms containing 1,10-phenanthroline; C-1044; C00604; M-5271; P 9375; 011P678; A835532; AA-860/25004133; Q416005; SR-01000076093; CU-00000000156-1; J-610043; SR-01000076093-1; W-104740; F3377-1129
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| Activity |
IC50 = 4000000 nM
|
[33] | |||
| Compound Name |
2,2'-Bipyridine
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Investigative | Compound Info | ||
| Synonyms |
2,2'-Dipyridyl; 2,2'-Bipyridyl; Bipyridine; 2,2'-Dipyridine; 2-(2-Pyridyl)pyridine; 2,2'-Bipyridin; alpha,alpha'-Dipyridyl; alpha,alpha'-Bipyridyl; Bipyridyl; alpha,alpha'-Dipyridine; AA-DP; 2,2-bipyridyl; dipyridyl; 2-pyridin-2-ylpyridine; 2-(pyridin-2-yl)pyridine; NSC 1550; MFCD00006212; .alpha.,.alpha.'-Bipyridine; [2,2]bipyridinyl; NSC 615009; UNII-551W113ZEP; alpha,alpha'-Bipyridine; Umdipyridyl; .alpha.,.alpha.'-Bipyridyl; .alpha.,.alpha.'-Dipyridyl; [2,2']BIPYRIDINYL; .alpha.,.alpha.'-Dipyridine; CHEMBL39879; MLS000069417; 551W113ZEP; CI 588; NSC615009; SMR000059069; 2,2'-Bipyridine, 99%; 2,2'-Dipyridyl, 99+%; 2,2-Bipyridine; 2,2 Bipyridyl; 2,2-Dipyridyl; 2,2' Bipyridine; CCRIS 3426; HSDB 5423; alpha,alpha'-Dwupirydylu [Polish]; alpha,alpha'-Dwupirydylu; EINECS 206-674-4; BRN 0113089; bi-pyridine; AI3-00491; 2-pyridylpyridine; 2,2bipyridyl; 2'2-bipyridine; 2,2'Bipyridine; 2, 2-Bipyridine; 2,2' bipyridyl; 2,2`-Bipyridine; [2,2']bipyridyl; 2,2''-bipyridyl; 2,2''-dipyridyl; 2,2''-bipyridine; 2,2''-dipyridine; 2,2'- bipyridine; 2,2\\'-bipyridine; 2,2''-Bipyridin; PubChem2134; alpha, alpha-Dipyridyl; 2-pyridin-2-ylpyridin; ACMC-209ino; alpha,alpha''-bipyridyl; alpha,alpha''-dipyridyl; alpha,alpha''-bipyridine; alpha,alpha''-dipyridine; Maybridge3_006205; Opera_ID_1615; Lopac-D-7505; 2,2'-Bipyridine, ACS; (aR)-2,2'-Bipyridine; (aS)-2,2'-Bipyridine; EC 206-674-4; SCHEMBL5922; UPCMLD00WV-71; DSSTox_CID_20635; DSSTox_RID_79518; DSSTox_GSID_40635; Lopac0_000471; 5-23-08-00016 (Beilstein Handbook Reference); KSC226A4T; 2,2'-Dipyridyl, ACS grade; WLN: T6NJ B- BT6NJ; DTXSID9040635; CTK1C6049; NSC1550; HMS1448K01; HMS2234F20; HMS3261O04; HMS3371D05; ZINC105227; ACT09618; BCP27263; NSC-1550; STR02551; Tox21_301430; Tox21_500471; ANW-28450; BDBM50042874; CCG-54708; RW2020; SBB079580; STL282738; AKOS004901459; 2,2'-Bipyridyl, p.a., 99.5%; AC-7556; AM81312; CS-W009134; FS-1056; LP00471; LS21121; MCULE-8524562351; NSC-615009; SC11754; SDCCGSBI-0050456.P002; IDI1_017592; NCGC00015364-01; NCGC00015364-02; NCGC00015364-03; NCGC00015364-04; NCGC00015364-05; NCGC00015364-07; NCGC00093368-02; NCGC00093368-03; NCGC00255575-01; NCGC00261156-01; 2,2'-Bipyridyl, >=98.0% (NT); AK-41113; BP-10293; BR-41113; SC-03874; 2,2'-Bipyridine;2-(pyridin-2-yl)pyridine; DB-013205; 2,2'-Bipyridyl, ReagentPlus(R), >=99%; B0468; EU-0100471; FT-0632048; FT-0636412; FT-0637152; ST50308286; 66D187; D 7505; D-7200; D-7250; D-7255; M-6336; 2,2'-Dipyridyl, JIS special grade, >=99.0%; 2,2'-Bipyridyl, Vetec(TM) reagent grade, 98%; Q209143; SR-01000075829; 2,2'-Bipyridyl, PESTANAL(R), analytical standard; SR-01000075829-1; SR-01000075829-3; Z57160161; F0001-1045
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||||
| Activity |
IC50 = 100000000 nM
|
[33] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis of 5,6-dihydro-11H-benzo[5,6]-cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidine-N-cyanoguanidine derivatives as inhibitors of ras farnesyl protein transferase. Bioorg Med Chem Lett. 2002 Feb 25;12(4):601-5. | ||||
| REF 2 | Ras farnesyltransferase: a new therapeutic target. J Med Chem. 1997 Sep 12;40(19):2971-90. | ||||
| REF 3 | Pyrazino[1,2-a]indole-1,4-diones, simple analogues of gliotoxin, as selective inhibitors of geranylgeranyltransferase I. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3661-3. | ||||
| REF 4 | Introduction of methionine mimics on 3-arylthiophene: influence on protein farnesyltransferase inhibition and on antiparasitic activity. Medchemcomm. 2013;4:1034-41. | ||||
| REF 5 | Improvement of the trypanocidal activity of 3-arylthiophene farnesyltransferase inhibitors by modulation of their 3-aryl group. Medchemcomm. 2012;3:1512-7. | ||||
| REF 6 | Multivariate data analysis using D-optimal designs, partial least squares, and response surface modeling: A directional approach for the analysis of farnesyltransferase inhibitors. J Med Chem. 2000 May 4;43(9):1807-16. | ||||
| REF 7 | 2-Arylindole-3-acetamides: FPP-competitive inhibitors of farnesyl protein transferase. Bioorg Med Chem Lett. 2001 Apr 9;11(7):865-9. | ||||
| REF 8 | Prenyltransferase Inhibitors: Treating Human Ailments from Cancer to Parasitic Infections. Medchemcomm. 2013 Mar;4(3):476-492. | ||||
| REF 9 | Clavaric acid and steroidal analogues as Ras- and FPP-directed inhibitors of human farnesyl-protein transferase. J Med Chem. 1998 Nov 5;41(23):4492-501. | ||||
| REF 10 | Potent, highly selective, and non-thiol inhibitors of protein geranylgeranyltransferase-I. J Med Chem. 1999 Apr 22;42(8):1333-40. | ||||
| REF 11 | Design, synthesis, and pharmacological evaluation of new farnesyl protein transferase inhibitors. J Med Chem. 2002 Jan 17;45(2):533-6. | ||||
| REF 12 | Farnesyl diphosphate-based inhibitors of Ras farnesyl protein transferase. J Med Chem. 1995 Jul 21;38(15):2906-21. | ||||
| REF 13 | Synthesis and biological evaluation of a new series of N-ylides as protein farnesyltransferase inhibitors. Bioorg Med Chem Lett. 2013 Nov 1;23(21):5887-92. | ||||
| REF 14 | Identification of novel farnesyl protein transferase inhibitors using three-dimensional database searching methods. J Med Chem. 1997 Dec 5;40(25):4103-12. | ||||
| REF 15 | Design, synthesis, and evaluation of sugar amino acid based inhibitors of protein prenyl transferases PFT and PGGT-1. J Med Chem. 2004 Jul 29;47(16):3920-3. | ||||
| REF 16 | Non-thiol 3-aminomethylbenzamide inhibitors of farnesyl-protein transferase. Bioorg Med Chem Lett. 1999 Jul 19;9(14):1991-6. | ||||
| REF 17 | Novel indolizine derivatives with unprecedented inhibitory activity on human farnesyltransferase. Bioorg Med Chem Lett. 2014 Dec 15;24(24):5777-5781. | ||||
| REF 18 | Discovery and structure-activity relationships of imidazole-containing tetrahydrobenzodiazepine inhibitors of farnesyltransferase. J Med Chem. 1999 Dec 16;42(25):5241-53. | ||||
| REF 19 | Neuroactive diol and acyloin metabolites from cone snail-associated bacteria. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4867-9. | ||||
| REF 20 | Towards the synthesis of bisubstrate inhibitors of protein farnesyltransferase: Synthesis and biological evaluation of new farnesylpyrophosphate analogues. Bioorg Med Chem. 2010 Jan 15;18(2):543-56. | ||||
| REF 21 | Phenol based tripeptide inhibitors of ras farnesyl protein transferase. Bioorg Med Chem Lett. 1994 Aug 11;4(15):1883-8. | ||||
| REF 22 | Phenothiazine-based CaaX competitive inhibitors of human farnesyltransferase bearing a cysteine, methionine, serine or valine moiety as a new family of antitumoral compounds. Bioorg Med Chem Lett. 2015 Oct 15;25(20):4447-52. | ||||
| REF 23 | Synthesis, pharmacological evaluation, and molecular modeling studies of novel peptidic CAAX analogues as farnesyl-protein-transferase inhibitors. J Med Chem. 2006 Mar 23;49(6):1882-90. | ||||
| REF 24 | 3D-QSAR studies of farnesyltransferase inhibitors: a comparative molecular field analysis approach. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1821-7. | ||||
| REF 25 | Synthesis and biological evaluation of a new series of phenothiazine-containing protein farnesyltransferase inhibitors. Eur J Med Chem. 2013 Jan;59:101-10. | ||||
| REF 26 | Peptidomimetic inhibitors of p21ras farnesyltransferase: Hydrophobic functionalization leads to disruption of p21ras membrane association in whole cells. Bioorg Med Chem Lett. 1994 Nov 10;4(21):2579-84. | ||||
| REF 27 | Synthesis and anti-migrative evaluation of moverastin derivatives. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1385-9. | ||||
| REF 28 | Local constrained shifty pseudopeptides inhibitors of rasfarnesyl transferase. Bioorg Med Chem Lett. 1995 Nov 16;5(22):2677-82. | ||||
| REF 29 | Oxo-piperazine derivatives of N-arylpiperazinones as inhibitors of farnesyltransferase. Bioorg Med Chem Lett. 2001 Feb 26;11(4):537-40. | ||||
| REF 30 | Design and synthesis of non-peptide Ras CAAX mimetics as potent farnesyltransferase inhibitors. J Med Chem. 1996 Jan 5;39(1):217-23. | ||||
| REF 31 | Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors. Eur J Med Chem. 2016 Feb 15;109:173-86. | ||||
| REF 32 | Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase. Bioorg Med Chem Lett. 2002 Jan 21;12(2):255-9. | ||||
| REF 33 | A novel metal-chelating inhibitor of protein farnesyltransferase. Bioorg Med Chem Lett. 2003 May 5;13(9):1523-6. | ||||
| REF 34 | Geranyl and neryl triazole bisphosphonates as inhibitors of geranylgeranyl diphosphate synthase. Bioorg Med Chem. 2014 May 1;22(9):2791-8. | ||||
| REF 35 | Hydroxamic acid-based bisubstrate analog inhibitors of Ras farnesyl protein transferase. J Med Chem. 1996 Oct 11;39(21):4197-210. | ||||
| REF 36 | Rational design of potent carboxylic acid based bisubstrate inhibitors of ras farnesyl protein transferase. Bioorg Med Chem Lett. 1994 Sep 8;4(17):2107-12. | ||||
| REF 37 | Kampanols: novel Ras farnesyl-protein transferase inhibitors from Stachybotrys kampalensis. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2071-6. | ||||
| REF 38 | A new class of type I protein geranylgeranyltransferase (GGTase I) inhibitor. Bioorg Med Chem Lett. 2002 Feb 25;12(4):629-32. | ||||
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