Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T16016 | Target Info | |||
| Target Name | C-C chemokine receptor type 1 (CCR1) | ||||
| Synonyms |
SCYAR1; RANTES-R; Macrophage inflammatory protein-1 alpha receptor; Macrophage inflammatory protein 1-alpha receptor; MIP-1alpha-R; LD78 receptor; HM145; Chemokine receptor CCR1; CMKR1; CMKBR1; CD191; CCR-1; CC-CKR-1; C-C CKR-1
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| Target Type | Clinical trial Target | ||||
| Gene Name | CCR1 | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 27 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
1-(4-Phenylbutyl)-4-benzylpiperidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL276784; 4-benzyl-1-(4-phenylbutyl)piperidine; SCHEMBL7374609; BDBM50034212
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(2,5-difluoro-phenyl)-urea
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL124583; SCHEMBL6216421; BDBM50117472; 1-[2-[(4-benzylpiperidin-1-yl)methyl]phenyl]-3-(2,5-difluorophenyl)urea
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
5-(4-Benzyl-piperazin-1-yl)-2,2-diphenyl-pentanenitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL124808; BDBM50117406
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
1,4-Dibenzylpiperidine
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Investigative | Compound Info | ||
| Synonyms |
1,4-Dibenzyl-piperidine; CHEMBL124457; Oprea1_204030; SCHEMBL2004615; CTK5J6201; BDBM50117399; STK028424; ZINC13475731; AKOS034442804; CCG-357732; MCULE-4544025245; NE21141; EN300-52825; AB01004471-01; Z54753294
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
11-Butyl-3-[1-(4,6-dimethylpyrimidine-5-carbonyl)-4-methyl-4-piperidyl]-9-[(4-ethoxycyclohexyl)methyl]-3,9-diazaspiro[5.5]undecan-10-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL449621; SCHEMBL3963928; BDBM50254750
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| Activity |
IC50 ~ 50000 nM
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[2] | |||
| Compound Name |
4-Benzyl-1-phenethyl-piperidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL18222; Piperidine, 1-(2-phenylethyl)-4-(phenylmethyl)-; ACMC-20mwaa; SCHEMBL7403790; CTK0F3764; DTXSID80442247; BDBM50007676; ZINC13475730; 1-(2-Phenylethyl)-4-benzylpiperidine; AKOS033184852; 4-BENZYL-1-(2-PHENYLETHYL)PIPERIDINE
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
1-(1-Benzyl-piperidin-4-yl)-3-[2-(4-benzyl-piperidin-1-ylmethyl)-phenyl]-urea
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL125108; SCHEMBL6220249; BDBM50117441; 1-(1-benzylpiperidin-4-yl)-3-[2-[(4-benzylpiperidin-1-yl)methyl]phenyl]urea
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
PharmaGSID_48521
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1078231; DSSTox_CID_28495; DSSTox_RID_82770; DSSTox_GSID_48521; DTXSID8048521; SCHEMBL18841093; Tox21_303454; BDBM50310739; NCGC00257432-01
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
5-(4-Benzyl-piperidin-1-yl)-2,2-diphenyl-pentanenitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL127395; BDBM50117425
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(2-piperidin-1-yl-ethyl)-urea
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL125325; SCHEMBL6701606; BDBM50117424; 1-[2-[(4-benzylpiperidin-1-yl)methyl]phenyl]-3-(2-piperidin-1-ylethyl)urea
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
N-[(2S,3S,5R)-5-Carbamoyl-7-(dimethylamino)-3-hydroxy-1-phenylheptan-2-yl]quinoxaline-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL420359; BDBM50144406
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| Activity |
IC50 = 55100 nM
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[4] | |||
| Compound Name |
2,2':6',2''-Terpyridine
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Investigative | Compound Info | ||
| Synonyms |
Tripyridyl; Tripyridine; 2,6-Bis(2-pyridyl)pyridine; terpy; 2,2',2''-Terpyridyl; 2,2',2''-Tripyridyl; 2,2',2''-Terpyridine; 2,6-dipyridin-2-ylpyridine; 2,2',2''-Tripyridine; Ba 2799; 2,6-Di(2-pyridyl)pyridine; 2,2'2''-Tripyridyl; TCMDC-123985; NSC 3905; UNII-G5E357ISH5; NSC 36755; 2,6-Di(pyridin-2-yl)pyridine; alpha,alpha',alpha''-Tripyridyl; NSC3905; [2,2';6',2'']Terpyridine; 2,2'6',2'-terpyridine; 2,2'6',2''-terpyridine; MLS000048666; G5E357ISH5; GNF-PF-4776; alpha,alpha',alpha''-Terpyridine; NSC36755; MFCD00006213; 2,2''-Terpyridyl; 2,2''-Tripyridyl; 2,2''-Terpyridine; 2,2''-Tripyridine; SMR000060049; 1(2),2(2):2(6),3(2)-terpyridine; .alpha.,.alpha.''-Tripyridyl; 2,2':6',2''-Terpyridine;2,2':6',2''-Terpyridine; 2,2':6',2''-Terpyridine, 96%; CCRIS 3429; EINECS 214-559-5; Alpha,Alpha,Alpha-Tripyridyl; a,a',a''-Tripyridyl; 6',2'']Terpyridine; Enamine_000115; 2,2:6,2-terpyridine; ACMC-1BOY0; NCIMech_000074; 2,6-dipyridin-2-ylpyridin; SCHEMBL57442; cid_70848; CHEMBL89445; 2,2',6',2 -Terpyridine; 2,2':6',2'-Terpyridine; alp.,alp.',alp.'-Tripyridyl; 2,6-bis(2-pyridinyl)pyridine; ZINC9065; DTXSID2061567; BDBM38924; CTK0H6322; HMS1394F05; HMS2456B12; KUC105324N; BCP33988; NSC-3905; ANW-16720; CCG-35469; KSC-8-139; NSC-36755; SBB008932; STK721799; 2,2\\':6\\',2\\'\\'-terpyridine; AKOS001032185; AM84346; CS-W004573; MCULE-7869708671; SC11759; 2,2',6',2''-TERPYRIDINE; KS-000002K6; .alpha.,.alpha.',.alpha.''-Tripyridyl; 2,2':6',2''-Terpyridine, 98%; .alpha.,.alpha.',.alpha.''-Terpyridine; AK-81483; CS-13012; NCI60_003699; SC-47295; ST085495; DB-050437; FT-0600048; T0024; Z3407; 2,2'':6'',2''''-TERPYRIDINE; 2,2',2''-TERPYRIDINE, 98+ %; 148T794; Q408228; J-400124; 2,2':6',2''-Terpyridine, for spectrophotometric det. of Ag, Fe, Ru, >=98.5%
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| Activity |
EC50 = 63095.73 nM
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[5] | |||
| Compound Name |
1,10-Phenanthroline
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Investigative | Compound Info | ||
| Synonyms |
o-phenanthroline; Phenanthroline; orthophenanthroline; 4,5-diazaphenanthrene; 1,10-o-phenanthroline; 2-phenanthroline; 1,10-Phenanthroline anhydrous; [1,10]phenanthroline; beta-phenanthroline; 1,10-Fenanthrolin; .beta.-Phenanthroline; 1,10-Phenanthroline, Anhydrous; MFCD00011678; UNII-W4X6ZO7939; MLS000069797; CHEMBL415879; NSC 4265; W4X6ZO7939; NSC203545; NSC4265; SMR000058190; DSSTox_CID_5857; pyridino[3,2-h]quinoline; DSSTox_RID_77950; DSSTox_GSID_25857; 1,10-Phenanthroline, 99+%; MLS002701886; 1,10-Fenanthrolin [Czech]; Activ-8; NSC-4265; CCRIS 4855; EINECS 200-629-2; NSC 203545; phenantroline; o-Phenanthrolin; Cyto5A5; 1,10-phenanthrolin; 1,10-phenantroline; 1,10-phenathroline; 1,10 phenanthroline; 1,10-Fenanthroline; 1.10-phenanthroline; 1,1 0-phenanthroline; ACMC-209nwd; Opera_ID_711; [1,10]-Phenanthroline; Lopac-P-9375; Activ-8 in hexylene glycol; cid_1318; SCHEMBL8312; NCIStruc1_000192; NCIStruc2_000199; Lopac0_000985; KSC241K8T; ARONIS014409; DTXSID1025857; WLN: T B666 CN NNJ; 1,10 CPhenanthroline anhydrous; NCI4265; 1,10-Phenanthroline (anhydrous); 1,10-Phenanthroline, >=99%; 1,10-Phenanthroline,hydrochloride; HMS2234D03; HMS3263E11; HMS3371F11; ZINC164363; KS-000044UM; Tox21_201998; Tox21_303111; Tox21_500985; ANW-35243; BDBM50092158; CCG-38059; NCGC00013043; s6830; SBB089685; STL069281; AKOS000281773; CS-W004544; DB02365; HY-W004544; LP00985; MCULE-2911225521; NSC-203545; SDCCGSBI-0050958.P003; NCGC00013043-02; NCGC00013043-03; NCGC00013043-04; NCGC00013043-05; NCGC00013043-06; NCGC00013043-07; NCGC00013043-08; NCGC00013043-09; NCGC00013043-10; NCGC00013043-13; NCGC00091201-01; NCGC00091201-02; NCGC00091201-03; NCGC00091201-04; NCGC00257123-01; NCGC00259547-01; NCGC00261670-01; AC-18353; AK-27000; AS-14043; BR-27000; NCI60_003976; SC-23392; DB-013750; EU-0100985; FT-0606035; FT-0660636; P0221; P0879; P1826; ST45051101; Solution forms containing 1,10-phenanthroline; C-1044; C00604; M-5271; P 9375; 011P678; A835532; AA-860/25004133; Q416005; SR-01000076093; CU-00000000156-1; J-610043; SR-01000076093-1; W-104740; F3377-1129
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| Activity |
IC50 = 74000 nM
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[5] | |||
| Compound Name |
(R)-N2-(4-Chlorobenzyl)-N1-(4-chlorophenyl)pyrrolidine-1,2-dicarboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL454941; BDBM50293032
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| Activity |
IC50 ~ 75000 nM
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[6] | |||
| Compound Name |
(R)-N2-(4-Methoxybenzyl)-N1-(4-chlorophenyl)-N2-methylpyrrolidine-1,2-dicarboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL517141; BDBM50293039
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| Activity |
IC50 ~ 77000 nM
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[6] | |||
| Compound Name |
4,4'-Dimethyl-2,2'-bipyridine
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Investigative | Compound Info | ||
| Synonyms |
4,4'-Dimethyl-2,2'-bipyridyl; 4,4'-Dimethyl-2,2'-dipyridyl; 2,2'-Bi-4-picoline; 2,2'-BIPYRIDINE, 4,4'-DIMETHYL-; 4-methyl-2-(4-methylpyridin-2-yl)pyridine; 2,2'-Bi(gamma-picoline); 2,2'-Bipyridyl, 4,4'-dimethyl-; MFCD00006441; 2,2'-Di-4-picolyl; NSC3261; CHEMBL101165; 4,4'-Dimethyl-2,2'-bipyridyl, 99+%; 4-methyl-2-(4-methyl(2-pyridyl))pyridine; NSC 3261; EINECS 214-483-2; 4,2'-bipyridine; 4,2'-dipyridyl; PubChem9622; 2, 4,4'-dimethyl-; ACMC-2099jr; 2,2'-Bi(gam.; KSC909E7H; SCHEMBL181893; 4,4'dimethyl 2,2'bipyridine; 4,4-Dimethyl-2,2-Bipyridyl; DTXSID3061552; CTK8A9273; KS-00000DTC; 2,2'-Bi-4-picoline (8CI); 4,4`-Dimethyl-2,2`-dipyridyl; 4,4' dimethyl 2,2' bipyridine; 4,4'-dimethyl 2,2'-bipyridine; ZINC120136; ACN-S002665; ACN-S003306; ACT08966; NSC-3261; 4,4'-Dimethyl-[2,2']bipyridinyl; 4,4\\'-Dimethyl-2,2\\'-bipyridyl; ANW-16645; BBL104382; BDBM50401350; RW1527; RW1982; SBB008769; STL558645; AKOS000344143; AC-5118; AM84345; CS-W002003; LS21016; MCULE-2447382595; SC11757; 4,4'-Dimethyl-2,2'-dipyridyl, 99%; AK-84390; AS-17512; SC-00426; SY011392; B0852; FT-0609153; ST50407480; V0506; B-6468; 134D356; 4,4'-Dimethyl-2,2'-dipyridyl, 99.5%, purified by sublimation; 4,4'-Dimethyl-2,2'-dipyridyl, for spectrophotometric det., >=99.0%
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| Activity |
IC50 = 100000 nM
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[5] | |||
| Compound Name |
(R)-N2-[4-(Trifluoromethyl)benzyl]-N1-(4-chlorophenyl)-N2-methylpyrrolidine-1,2-dicarboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL462611; BDBM50293040
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| Activity |
IC50 ~ 100000 nM
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[6] | |||
| Compound Name |
1,10-Phenanthroline-4,7-diol
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Investigative | Compound Info | ||
| Synonyms |
4,7-Dihydroxy-1,10-phenanthroline; 1,10-Phenanthroline-4,7(1H,10H)-dione; MFCD00004975; CHEMBL1623498; 1,10-dihydro-1,10-phenanthroline-4,7-dione; 1,4,7,10-tetrahydro-1,10-phenanthroline-4,7-dione; pyridino[3,2-h]quinoline-4,7-diol; EINECS 223-493-6; ACMC-1COEH; Oprea1_631021; BIDD:GT0532; 1,1-Phenanthroline-4,7-diol; SCHEMBL1073354; DTXSID0063234; SCHEMBL19318056; CTK1C2783; KS-00000NVS; [1,10]phenanthroline-4,7-diol; 4,7-Dioxylato-1,10-phenanthroline; 5123AB; ANW-29036; BDBM50401357; SBB008750; STK700952; ZINC12341711; AKOS000520806; AKOS015918059; CS-W004566; DS-3423; MCULE-7566362799; NCGC00246264-01; AK106224; SC-08302; DB-050452; ST4066281; D3869; FT-0707691; 4,7-Dihydroxy-1,10-phenanthroline, Dye content >=30 %; 1,10-phenanthroline-4,7-diol4,7-dihydroxy-1,10-phenanthroline
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| Activity |
EC50 ~ 100000 nM
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[5] | |||
| Compound Name |
(R)-N2-(4-Chloro-2-methylbenzyl)-N1-(4-chlorophenyl)-N2-methylpyrrolidine-1,2-dicarboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL460534; BDBM50293043
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| Activity |
IC50 ~ 100000 nM
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[6] | |||
| Compound Name |
(R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[4-(trifluoromethyl)phenyl]azetidine-1,2-dicarboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL472912; BDBM50293057
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| Activity |
IC50 ~ 100000 nM
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[6] | |||
| Compound Name |
4,7-Dimethyl-1,10-phenanthroline
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Investigative | Compound Info | ||
| Synonyms |
4,7-Dimethyl-o-phenanthroline; 4,7-DIMETHYL-[1,10]PHENANTHROLINE; 1,10-Phenanthroline, 4,7-dimethyl-; MFCD00004979; UNII-P3YJ54Z8ZO; P3YJ54Z8ZO; CHEMBL593442; 4,7-dimethylpyridino[3,2-h]quinoline; ACMC-1CJN6; Oprea1_825186; SCHEMBL182930; DTXSID9062932; CTK3J6706; KS-00000NVT; NSC4281; ZINC120461; ALBB-023379; NSC 4281; NSC-4281; EINECS 221-827-5; ANW-13810; BDBM50401348; SBB008716; AKOS003369115; CS-W004562; DB02586; DS-2431; NCGC00247283-01; AK-84388; ST078007; SY037737; DB-050425; D0772; FT-0634746; R2743; 1,10-phenanthroline, 4,7-dimethyl-, hydrate; 248D053; Q27093559; 5-Fluoro-l-(2-furanidinyl)-4-(trimethylsilyloxy)-2-pyrimidone
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| Activity |
IC50 = 100000 nM
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[5] | |||
| Compound Name |
(R)-N2-(3-Chlorobenzyl)-N1-(4-chlorophenyl)-N2-(2-hydroxyethyl)pyrrolidine-1,2-dicarboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL462612; BDBM50293037
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| Activity |
IC50 ~ 100000 nM
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[6] | |||
| Compound Name |
5-Methyl-1,10-phenanthroline
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Investigative | Compound Info | ||
| Synonyms |
1,10-Phenanthroline, 5-methyl-; 5-Methylphenanthroline; CHEMBL98682; 1,10-Phenanthroline,5-methyl-; 5-Methyl-1,10-phenanthroline Hydrate [for Colorimetric Determination of Iron]; NSC 4272; EINECS 221-099-9; MFCD00004982; ACMC-1AGCX; SCHEMBL371564; DTXSID4062771; 5-Methyl-[1,10]phenanthroline; CTK4G4216; UJAQYOZROIFQHO-UHFFFAOYSA-; NSC4272; 5-methylpyridino[3,2-h]quinoline; ZINC120047; KS-000015CR; NSC-4272; BDBM50401345; AKOS015899630; CS-W004552; MCULE-2835878219; 5-Methyl-1,10-phenanthroline, >=99%; AC-29167; AS-59411; DB-050453; FT-0620583; M0300; ST50308418; 2-BROMO-5-(2,5-DIMETHYL)PYRROLIDYLPYRIDINE; J-200078; iron(+2) cation; 5-methyl-1,10-phenanthroline; sulfate; 5-Methyl-1,10-phenanthrolineHydrate[forColorimetricDeterminationofIron]
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| Activity |
IC50 = 119000 nM
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[5] | |||
| Compound Name |
2,2'-Bipyridine
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Investigative | Compound Info | ||
| Synonyms |
2,2'-Dipyridyl; 2,2'-Bipyridyl; Bipyridine; 2,2'-Dipyridine; 2-(2-Pyridyl)pyridine; 2,2'-Bipyridin; alpha,alpha'-Dipyridyl; alpha,alpha'-Bipyridyl; Bipyridyl; alpha,alpha'-Dipyridine; AA-DP; 2,2-bipyridyl; dipyridyl; 2-pyridin-2-ylpyridine; 2-(pyridin-2-yl)pyridine; NSC 1550; MFCD00006212; .alpha.,.alpha.'-Bipyridine; [2,2]bipyridinyl; NSC 615009; UNII-551W113ZEP; alpha,alpha'-Bipyridine; Umdipyridyl; .alpha.,.alpha.'-Bipyridyl; .alpha.,.alpha.'-Dipyridyl; [2,2']BIPYRIDINYL; .alpha.,.alpha.'-Dipyridine; CHEMBL39879; MLS000069417; 551W113ZEP; CI 588; NSC615009; SMR000059069; 2,2'-Bipyridine, 99%; 2,2'-Dipyridyl, 99+%; 2,2-Bipyridine; 2,2 Bipyridyl; 2,2-Dipyridyl; 2,2' Bipyridine; CCRIS 3426; HSDB 5423; alpha,alpha'-Dwupirydylu [Polish]; alpha,alpha'-Dwupirydylu; EINECS 206-674-4; BRN 0113089; bi-pyridine; AI3-00491; 2-pyridylpyridine; 2,2bipyridyl; 2'2-bipyridine; 2,2'Bipyridine; 2, 2-Bipyridine; 2,2' bipyridyl; 2,2`-Bipyridine; [2,2']bipyridyl; 2,2''-bipyridyl; 2,2''-dipyridyl; 2,2''-bipyridine; 2,2''-dipyridine; 2,2'- bipyridine; 2,2\\'-bipyridine; 2,2''-Bipyridin; PubChem2134; alpha, alpha-Dipyridyl; 2-pyridin-2-ylpyridin; ACMC-209ino; alpha,alpha''-bipyridyl; alpha,alpha''-dipyridyl; alpha,alpha''-bipyridine; alpha,alpha''-dipyridine; Maybridge3_006205; Opera_ID_1615; Lopac-D-7505; 2,2'-Bipyridine, ACS; (aR)-2,2'-Bipyridine; (aS)-2,2'-Bipyridine; EC 206-674-4; SCHEMBL5922; UPCMLD00WV-71; DSSTox_CID_20635; DSSTox_RID_79518; DSSTox_GSID_40635; Lopac0_000471; 5-23-08-00016 (Beilstein Handbook Reference); KSC226A4T; 2,2'-Dipyridyl, ACS grade; WLN: T6NJ B- BT6NJ; DTXSID9040635; CTK1C6049; NSC1550; HMS1448K01; HMS2234F20; HMS3261O04; HMS3371D05; ZINC105227; ACT09618; BCP27263; NSC-1550; STR02551; Tox21_301430; Tox21_500471; ANW-28450; BDBM50042874; CCG-54708; RW2020; SBB079580; STL282738; AKOS004901459; 2,2'-Bipyridyl, p.a., 99.5%; AC-7556; AM81312; CS-W009134; FS-1056; LP00471; LS21121; MCULE-8524562351; NSC-615009; SC11754; SDCCGSBI-0050456.P002; IDI1_017592; NCGC00015364-01; NCGC00015364-02; NCGC00015364-03; NCGC00015364-04; NCGC00015364-05; NCGC00015364-07; NCGC00093368-02; NCGC00093368-03; NCGC00255575-01; NCGC00261156-01; 2,2'-Bipyridyl, >=98.0% (NT); AK-41113; BP-10293; BR-41113; SC-03874; 2,2'-Bipyridine;2-(pyridin-2-yl)pyridine; DB-013205; 2,2'-Bipyridyl, ReagentPlus(R), >=99%; B0468; EU-0100471; FT-0632048; FT-0636412; FT-0637152; ST50308286; 66D187; D 7505; D-7200; D-7250; D-7255; M-6336; 2,2'-Dipyridyl, JIS special grade, >=99.0%; 2,2'-Bipyridyl, Vetec(TM) reagent grade, 98%; Q209143; SR-01000075829; 2,2'-Bipyridyl, PESTANAL(R), analytical standard; SR-01000075829-1; SR-01000075829-3; Z57160161; F0001-1045
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| Activity |
IC50 = 125892.54 nM
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[5] | |||
| Compound Name |
3,4,7,8-Tetramethyl-1,10-phenanthroline
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Investigative | Compound Info | ||
| Synonyms |
1,10-Phenanthroline, 3,4,7,8-tetramethyl-; 3,4,7,8-Tetramethylphenanthroline; MFCD00004974; CHEMBL99384; 3,4,7,8-Tetramethyl-[1,10]phenanthroline; 3,4,7,8-tetramethylpyridino[3,2-h]quinoline; 3,4,7,8-Tetramethyl-1, 10-phenanthroline; 3,4,7,8-Tetramethyl-1,10-phenanthroline, 99+%; EINECS 216-762-4; ACMC-209dtn; 3,4,7,8-Me4Phenan; BIDD:GT0406; SCHEMBL136654; DTXSID2061856; CTK3J6867; 3,4,7,8-tetramethylphenantroline; ZINC119661; BCP11189; CS-D1715; ANW-22185; BBL102541; BDBM50401347; SBB008945; STL556344; AKOS007930862; AC-1871; ACN-025337; AM84569; MCULE-3066359229; KS-00000E65; AK-63875; AS-15524; SC-23606; ST080673; SY004672; 3,4,7,8-tetramethyl-1,10-phenanthrolin; 3,4,7,8-tetramethyl-1,10-phenantroline; 3`4`7`8-Tetramethyl-1`10-phenanthroline; DB-050424; 3, 4,7,8-tetramethyl-1,10-phenanthrolin; FT-0614180; 3,4,7,8-Tetramethyl-1,10-diazaphenanthrene; 660T931; W-107928; 3,4,7,8-Tetramethyl-1,10-phenanthroline, >=98%
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| Activity |
IC50 = 158489.32 nM
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[5] | |||
| Compound Name |
4,4'-Dimethoxy-2,2'-bipyridine
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Investigative | Compound Info | ||
| Synonyms |
4,4'-Dimethoxy-2,2'-bipyridyl; 4-methoxy-2-(4-methoxypyridin-2-yl)pyridine; 4,4'-Dimethoxy-[2,2']bipyridinyl; 2,2'-Bipyridine, 4,4'-dimethoxy-; CHEMBL2205808; MFCD00233880; MeO-bpy; 4-4'-Dimethoxy-2-2'-bipyridine; ACMC-1C6X1; SCHEMBL182529; CTK0I3310; DTXSID50370043; ZINC403962; KS-000002EK; 4,4'-dimethoxy-2,2'- bipyridine; ANW-22557; BDBM50401349; AKOS015851874; CS-W004762; VP14604; AC-20760; AK-63314; DS-15216; SC-65740; SY038948; 4-4'-Dimethoxy-2-2'-bipyridine, 97%; D3886; FT-0647788; ST50405823; 4-methoxy-2-(4-methoxy(2-pyridyl))pyridine; 4-methoxy-2-(4-methoxy-2-pyridinyl)pyridine; A811383
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| Activity |
IC50 = 179000 nM
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[5] | |||
| Compound Name |
Abametapir
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Investigative | Compound Info | ||
| Synonyms |
5,5'-Dimethyl-2,2'-bipyridine; 5,5'-Dimethyl-2,2'-dipyridyl; 5,5'-Dimethyl-2,2'-bipyridyl; 6,6'-Bi-3-picoline; 2,2'-BIPYRIDINE, 5,5'-DIMETHYL-; HA-44; 6,6'-Di-3-picolyl; 6,6'-Di-3-picoline; UNII-6UO390AMFB; 5-methyl-2-(5-methylpyridin-2-yl)pyridine; MFCD01740554; 6UO390AMFB; CHEMBL2205807; 5,5'-dimethyl-2,2'-bipyridinyl; 5,5 -Dimethyl-2,2 -bipyridine; Xeglyze; BRN 0123183; Abametapir [USAN:INN]; Xeglyze(Abametapir); Xeglyze (TN); PubChem24353; Abametapir (USAN/INN); ACMC-209eb4; SCHEMBL351152; 2,2 -Bis-(5-methylpyridyl); DTXSID00170095; ZINC403335; 9238AA; ANW-22814; BDBM50401351; LT0042; s5752; 5,5''-Dimethyl-2,2''-bipyridine; AKOS005257775; CS-W004546; DB11932; MCULE-8581798506; SB17220; 5,5'-Dimethyl-2,2'-dipyridyl, 98%; AK-63331; DS-15219; SY052805; FT-0689891; D10687; W-108621; Q27265547
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| Activity |
IC50 = 199526.23 nM
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[5] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 6 non binders) | Download | Top | |||
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| Compound Name |
4-Methyl-1,10-phenanthroline
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Investigative | Compound Info | ||
| Synonyms |
1,10-Phenanthroline, 4-methyl-; MFCD00004978; CHEMBL316589; 4-methylpyridino[3,2-h]quinoline; ACMC-1AIHJ; cid_93149; MLS001359987; SCHEMBL912010; DTXSID2067612; 4-Methyl-[1,10]phenanthroline; CTK3J6175; HMS3025J12; ZINC120467; 3351AB; ANW-66139; BDBM50401346; SBB009139; AKOS015916743; 4-Methyl-1,10-phenanthroline, 97%; CS-W004551; MCULE-4398278647; NCGC00247290-01; AC-29166; AS-59410; SMR001224335; ST080587; FT-0692529; 4-Methyl-1,10-phenanthroline1,10-phenanthroline, 4-Methyl-
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| Activity |
IC50 = 251188.64 nM
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[5] | |||
| Compound Name |
2,6-Bis(2-pyridyl)-4(1H)-pyridone
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Investigative | Compound Info | ||
| Synonyms |
[2,2':6',2''-Terpyridin]-4'-ol; [2,2':6',2''-Terpyridin]-4'(1'H)-one; 2,6-dipyridin-2-yl-1H-pyridin-4-one; 2,2':6',2''-Terpyridin-4'-ol; CHEMBL2205804; MFCD01321386; [2,2,6,2-terpyridin]-4(1H)-one; 4'-HYDROXY-2,2':6',2''-TERPYRIDINE; 4-Terpyridone; ACMC-209bep; 1'H-[2,2',6',2'']Terpyridin-4'-one; ACMC-20m41v; SCHEMBL1988750; CTK0H0167; CTK0H4325; KS-00000USR; ZINC403259; KS-00001KN4; 2,6-bis-pyridyl-4-(1H)-pyridone; ANW-19055; BDBM50401356; MFCD06796976; 2,6-bis(2-pyridyl)-4(1H)pyridone; 2,6-Bis(pyridin-2-yl)pyridin-4-ol; AKOS015912996; AKOS015914629; 2,6-Di(2-pyridyl)-4(1H)-pyridone; 2,6-bis(pyridin-2-yl)-4(1h)-pyridone; AC-27853; AS-62574; SC-70393; SY052797; 2,6-di(pyridin-2-yl)pyridin-4(1h)-one; Z2460; 1'H-[2,2';6',2'']terpyridin-4'-on; 1'H-[2,2';6',2'']terpyridin-4'-one; 1'H-[2,2';6',2'']terpyridine-4'-one; 2,6-?Bis(2-?pyridyl)?-?4(1H)-pyridone; 2,6-Bis(pyridine-2-yl)pyridine-4(1H)-one; 6-(pyridin-2-yl)-[2,2'-bipyridine]-4-ol; 1'H-[2,2';6',2 '']terpyridine-4'-one; 2,6-Bis(2-pyridyl)-4(1H)-pyridone, 98%; J-005568; J-400598; 6-(pyridin-2-yl)-1,4-dihydro-[2,2'-bipyridin]-4-one
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| Activity |
EC50 > 1000000 nM
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[5] | |||
| Compound Name |
Neocuproine
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Investigative | Compound Info | ||
| Synonyms |
2,9-Dimethyl-1,10-phenanthroline; 1,10-Phenanthroline, 2,9-dimethyl-; Neocuproin; 2,9-Dimethylphenanthroline; 2,9-Dimethyl-o-phenanthroline; neo-Cuproin; DMPHEN; Neocuproine hemihydrate; NSC4280; UNII-8E7D2SH3BV; 8E7D2SH3BV; MLS001194484; GNF-PF-5611; MFCD00004973; SMR000555011; DMPHEN; NSC 4280; Neocuproin; VUF 7738; 2,9-dimethylpyridino[3,2-h]quinoline; MFCD00149306; NSC 4280; EINECS 207-601-9; 2,9-Dimethyl-1,10-phenanthroline hemihydrate, 98%; 2,10-phenanthroline; Neocuproine, >=98%; 1, 2,9-dimethyl-; NCIMech_000034; Oprea1_068014; cid_65237; KSC496I5N; 484-11-7 (anhydrous); SCHEMBL124563; CHEMBL375781; DTXSID5060065; BDBM64740; CTK3J6456; HMS2230M06; HMS3373K19; KUC107774N; ZINC119332; 2,10-dimethyl-1,9-phenanthroline; BCP18357; DNDI1343110; KS-00000VG9; KSC-09-264B; NSC-4280; 2,9-di-methyl-1,10-phenanthroline; 3,6-Dimethyl-4,5-diazaphenanthrene; ANW-41947; CCG-16034; CCG-35468; SBB008718; AKOS000511700; CS-W004563; MCULE-3651567163; NCGC00245843-01; AK134888; AS-14894; NCI60_003986; SC-18587; ST013881; SY010909; DB-050426; D0771; EU-0036872; FT-0610770; Neocuproine, Vetec(TM) reagent grade, 98%; A-8054; 2,9-Dimethyl-1,10-phenanthroline Neocuproine; AB00443806-10; AB00443806-12; A827529; Q409347; J-610070; BRD-K16598630-001-05-7; Z2301294930; 2,9-DIMETHYL-1,10-PHENANTHROLINE, REAGENT (ACS)
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| Activity |
IC50 > 1000000 nM
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[5] | |||
| Compound Name |
1,10-Phenanthroline-4,7-dicarbaldehyde
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2205801; 1,10-Phenanthroline-4,7-dicarboxaldehyde; SCHEMBL1088410; BDBM50401343; ZINC95558531; J-400085
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| Activity |
IC50 > 1000000 nM
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[5] | |||
| Compound Name |
2,9-Bis(bromomethyl)-1,10-phenanthroline
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Investigative | Compound Info | ||
| Synonyms |
NSC602850; CHEMBL1976682; SCHEMBL1258482; CTK2G4820; DTXSID70326587; ZINC1608162; BDBM50401340; NSC-602850; NCI60_004569; 1,10-Phenanthroline, 2,9-bis(bromomethyl)-
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| Activity |
IC50 > 1000000 nM
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[5] | |||
| Compound Name |
1,10-Phenanthroline-2,9-diyldimethanol
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Investigative | Compound Info | ||
| Synonyms |
(1,10-Phenanthroline-2,9-diyl)dimethanol; [9-(hydroxymethyl)-1,10-phenanthrolin-2-yl]methanol; NSC353096; UNII-1BR6ZZ33GT; 1BR6ZZ33GT; 2,9-Bis(hydroxymethyl)-1,10-phenanthroline; CHEMBL2205802; NSC 353096; SCHEMBL5301328; CTK5E6149; DTXSID90229329; ZINC391500; BDBM50401342; 1,10-Phenanthroline-2,9-dimethanol; NSC-353096; 2.9-Bis(hydroxymethyl)-1,10-phenanthroline; (9-Hydroxymethyl-[1,10]phenanthrolin-2-yl)-methanol
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| Activity |
IC50 > 1000000 nM
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[5] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery and structure-activity relationship of N-(ureidoalkyl)-benzyl-piperidines as potent small molecule CC chemokine receptor-3 (CCR3) antagonists. J Med Chem. 2002 Aug 15;45(17):3794-804. | ||||
| REF 2 | Discovery of a potent, selective and orally bioavailable 3,9-diazaspiro[5.5]undeca-2-one CCR5 antagonist. Bioorg Med Chem Lett. 2009 Jan 1;19(1):209-13. | ||||
| REF 3 | Spiropiperidine CCR5 antagonists. Bioorg Med Chem Lett. 2009 Sep 15;19(18):5401-6. | ||||
| REF 4 | Potent small molecule CCR1 antagonists. Bioorg Med Chem Lett. 2004 May 3;14(9):2169-73. | ||||
| REF 5 | Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors. J Med Chem. 2012 Sep 27;55(18):8164-77. | ||||
| REF 6 | Novel pyrrolidine ureas as C-C chemokine receptor 1 (CCR1) antagonists. J Med Chem. 2009 Mar 12;52(5):1295-301. | ||||
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