Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T22658 | Target Info | |||
| Target Name | Interleukin-8 (IL8) | ||||
| Synonyms |
T-cell chemotactic factor; Protein 3-10C; Neutrophil-activating protein 1; NAP-1; Monocyte-derived neutrophil-activating peptide; Monocyte-derived neutrophil chemotactic factor; MONAP; MDNCF; IL8; IL-8; Granulocyte chemotactic protein 1; GCP-1; Emoctakin; Chemokine (C-X-C motif) ligand 8; C-X-C motif chemokine 8
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| Target Type | Successful Target | ||||
| Gene Name | CXCL8 | ||||
| Biochemical Class | Cytokine: interleukin | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Interleukin-8 inhibitor, 6
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3856124; CHEMBL2370828; BDBM50291121
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| Activity |
Ki = 106000 nM
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[1] | |||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Interleukin-8 inhibitor, 4
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3856134; CHEMBL2370827; BDBM50291129
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| Activity |
Ki = 383000 nM
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[1] | |||
| References | Top | ||||
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| REF 1 | Peptide based inhibitors of interleukin-8: structural simplification and enhanced potency. Bioorg Med Chem Lett. 1997 Feb 18;7(4):429-32. | ||||
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