Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T27466 | Target Info | |||
| Target Name | Bromodomain and PHD finger containing 3 (BRPF3) | ||||
| Synonyms |
KIAA1286; Bromodomain and PHD finger-containing protein 3
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| Target Type | Literature-reported Target | ||||
| Gene Name | BRPF3 | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 3 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
PMID25408830C3
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Investigative | Compound Info | ||
| Synonyms |
GSK-5959; 901245-65-6; GSK5959; GSK 5959; 4uye; GTPL7811; MolPort-004-921-361; HMS1821D17; EX-A2263; BCP16039; ZINC8594565; BDBM50032912; AKOS000481208; MCULE-6727694163; CS-4867; NCGC00107508-01; HY-18665; C301-5895; 9F9; N-[
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
4-Cyano-N-(1,3-diethyl-2-oxoquinolin-6-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4059509; BDBM50249797
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| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
1-Methyl-2-oxo-N-phenylquinoline-6-sulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4072276; BDBM50249769
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| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | 1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain. ACS Med Chem Lett. 2014 Sep 10;5(11):1190-5. | ||||
| REF 2 | Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins. J Med Chem. 2017 Aug 24;60(16):6998-7011. | ||||
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