Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T50547 | Target Info | |||
| Target Name | Plasmodium Plasmepsin 1 (Malaria PLA1) | ||||
| Synonyms |
Plasmepsin I; PFAPG; Aspartic hemoglobinase I
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| Target Type | Literature-reported Target | ||||
| Gene Name | Malaria PLA1 | ||||
| Biochemical Class | Peptidase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
2-Amino-7-phenyl-3-[(4-phenyloxolan-2-yl)methyl]quinazolin-4-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3765557; BDBM50145779
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| Activity |
IC50 = 52000 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV. J Med Chem. 2016 Jan 14;59(1):374-87. | ||||
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