Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T59626 | Target Info | |||
| Target Name | Leukotriene B4 receptor 1 (LTB4R) | ||||
| Synonyms |
P2Y7; P2Y purinoceptor 7; P2RY7; Leukotriene B(4) receptor BLT1; LTB4-R1; LTB4-R 1; LTB4-R; GPR16; G-protein coupled receptor 16; Chemoattractant receptor-like 1; CMKRL1; BLTR; BLT1; BLT
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| Target Type | Clinical trial Target | ||||
| Gene Name | LTB4R | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 3 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
PMID28766366-Compound-Scheme27LeucettamineB
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Patented | Compound Info | ||
| Activity |
Ki = 100000 nM
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[1] | |||
| Compound Name |
Sodium;4-[(1R,3S)-1-hydroxy-3-[(E)-3-hydroxyoct-1-enyl]cyclohexyl]butanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL305933
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| Activity |
IC50 = 70000 nM
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[2] | |||
| Compound Name |
Sodium;2-[(1S,3S)-1-hydroxy-3-[(E)-3-hydroxy-7-phenylhept-1-enyl]cyclohexyl]acetate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL77513
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| Activity |
IC50 = 70000 nM
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[2] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Studies on the acetogenins of Formosan annonaceous plants. II. Cytotoxic acetogenins from Annona reticulata. J Nat Prod. 1993 Oct;56(10):1688-94. | ||||
| REF 2 | Synthesis and pharmacological profile of new 1,3-disubstituted cyclohexanes as leukotriene B4 receptor antagonists. Bioorg Med Chem Lett. 1996 Oct 8;6(19):2349-54. | ||||
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