Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T62151 | Target Info | |||
| Target Name | Monoamine oxidase (MAO) | ||||
| Synonyms |
Human monoamine oxidase
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| Target Type | Successful Target | ||||
| Gene Name | NO-GeName | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 3 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
1-[5-(2-Chloro-phenyl)-3-(4-hydroxy-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL63223; BDBM50292160
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| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
1-Phenylcyclopropanemethylamine
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Investigative | Compound Info | ||
| Synonyms |
(1-phenylcyclopropyl)methanamine; (1-phenylcyclopropyl)methylamine; 1-(Phenylcyclopropyl)methylamine; Cyclopropanemethanamine, 1-phenyl-; CHEMBL61251; 1-(1-PHENYLCYCLOPROPYL)METHANAMINE; [(1-phenylcyclopropyl)methyl]amine; MFCD06213079; C-(1-Phenyl-cyclopropyl)-methylamine; (phenylcyclopropyl)methylamine; 1-phenylcyclopropanemethanamine; EINECS 213-302-4; ACMC-209rmd; 1-Phenylcyclopropylmethanamine; 1-phenylcyclopropylmethylamine; SCHEMBL1492704; CTK5H2632; 1-(phenyl-cyclopropyl)methylamine; DTXSID20239451; ALBB-024886; ZINC1845507; ANW-40067; BDBM50026628; SBB052398; {1-(1-Phenylcyclopropyl)}methylamine; AKOS000345257; AB23375; MCULE-6201730315; KS-00003T15; SC-13084; SY168890; TS-01934; 1-phenylcyclopropanemethylamine, AldrichCPR; AB0062557; DB-079606; FT-0708878; R9114; ST45028018; V9281; EN300-25779; A846017
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| Activity |
Ki = 50000 nM
|
[2] | |||
| Compound Name |
1-Benzylcyclopropylamine
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Investigative | Compound Info | ||
| Synonyms |
1-benzylcyclopropanamine; 1-benzylcyclopropan-1-amine; Cyclopropanamine, 1-(phenylmethyl)-; 1-Benzyl-cyclopropylamine; CHEMBL58222; 1-Benzyl-1-cyclopropanamine; SCHEMBL1318340; CTK4F9034; DTXSID30181533; Cyclopropanamine,1-(phenylmethyl)-; ALBB-012211; ZINC6096117; BDBM50225448; AKOS004119743; MCULE-1660620797; DB-013100; BB 0222333; CS-0088458; FT-0683116; Y-4103
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| Activity |
Ki = 51000 nM
|
[2] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis and selective inhibitory activity of 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives against monoamine oxidase. J Med Chem. 2004 Apr 8;47(8):2071-4. | ||||
| REF 2 | 1-Benzylcyclopropylamine and 1-(phenylcyclopropyl)methylamine: an inactivator and a substrate of monoamine oxidase. J Med Chem. 1985 Dec;28(12):1953-7. | ||||
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