Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T68547 | Target Info | |||
| Target Name | Histone deacetylase 1 (HDAC1) | ||||
| Synonyms |
RPD3L1; HD1
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|
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| Target Type | Successful Target | ||||
| Gene Name | HDAC1 | ||||
| Biochemical Class | Carbon-nitrogen hydrolase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 158 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Imatinib
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|
Approved | Compound Info | ||
| Synonyms |
Cgp 57148; Glamox; Glamox (TN); Gleevec (TN); Glivec (TN); Imatinib (INN); Imatinib (STI571); Imatinib Methansulfonate; Imatinib [INN:BAN]; 112GI019; 152459-95-5; BKJ8M8G5HI; CCRIS 9076; CGP-57148; CHEMBL941; Imatinib free base; STI; UNII-BKJ8M8G5HI
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|
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
(S)-2-Amino-N-cyclopentyl-7-mercaptoheptanamide
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|
Investigative | Compound Info | ||
| Synonyms |
thiolate analogue, 26a; CHEMBL235911; SCHEMBL16338810; BDBM19139
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|
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| Activity |
IC50 = 52300 nM
|
[2] | |||
| Compound Name |
N-hydroxy-1-naphthamide
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|
Investigative | Compound Info | ||
| Synonyms |
1-Naphthohydroxamic acid; 6953-61-3; N-Hydroxy-1-naphthamide; 1-NAPHTHALENECARBOXAMIDE, N-HYDROXY-; NSC 57457; N-Hydroxynaphthalene-1-carboxamide; alpha-Naphthohydroxamic acid; a-Naphthohydroxamic acid; BRN 2094470; CHEMBL115468; Naphthalene-1-carboxylic acid hydroxyamide; 8GK; naphthylhydroxamic acid; AC1L2M8D; N-Hydroxy-1-naphthamide #; 4-09-00-02407 (Beilstein Handbook Reference); .alpha.-Naphthohydroxamic acid; ACMC-209o98; SCHEMBL2230679; CTK5D0341; DTXSID30219789; JRZGPWOEHDOVMC-UHFFFAOYSA-N
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-hydroxy-4-(naphthalen-1-yl)benzamide
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|
Investigative | Compound Info | ||
| Synonyms |
N-Hydroxy-4-naphthalen-1-yl-benzamide
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Biphenyl-3-carboxylic acid hydroxyamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL154517; Biphenyl-3-carboxylic acid hydroxyamide; 3-biphenyl hydroxamic acid; 3-Phenylbenzohydroximic acid; SCHEMBL10363097; SEPGPMDDTZHYJV-UHFFFAOYSA-N; ZINC27646665
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
PCI-34051
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|
Investigative | Compound Info | ||
| Synonyms |
PCI-34259; PCI-34260; PCI-40505; PCI-43744; PCI-45159; PCI-47634; PCI-48000; PCI-48001; PCI-48002; PCI-48003; PCI-48004; PCI-48006; PCI-48007; PCI-48008; PCI-48009; PCI-48010; PCI-48011; PCI-48012; PCI-48013; PCI-48018; PCI-48036; PCI-48039; HDAC 8 inhibitors (cancer/inflammation); HDAC 8 inhibitors (cancer/inflammation), Pharmacyclics
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|
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| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
N-hydroxy-3-(naphthalen-1-yl)acrylamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL245548; N-hydroxy-3-(naphthalen-1-yl)acrylamide; SCHEMBL14106948; BDBM50207560; (E)-3-(1-Naphthalenyl)-2-propenehydroximic acid
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|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
NQN-1
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|
Investigative | Compound Info | ||
| Synonyms |
PPM-18; NSC 73233
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|
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| Activity |
IC50 ~ 180000 nM
|
[5] | |||
| Compound Name |
N-(2-Amino-5-chlorophenyl)nicotinamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL255985; CTK6G8696; BDBM50374027; AKOS000127152
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(1R,2R,3R)-N-Hydroxy-2-(1-methylpyrazol-4-yl)-3-phenylcyclopropane-1-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110023; SCHEMBL12499732; BDBM50446477
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
N-(2-Amino-5-morpholin-4-ylphenyl)pyridine-3-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL272152; BDBM50374033
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(2E)-3-(3-Bromo-4-methoxyphenyl)-2-methoxyimino-N-(2-methylsulfanylethyl)propanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2047543; BDBM50386459
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|
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
Benzyl N-(2-hydroxy-5-phenylphenyl)carbamate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL256649; BDBM50374012
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|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
3-(Benzylamino)propionohydroxamic acid monohydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4078522; Propanamide, N-hydroxy-3-[(phenylmethyl)amino]-; Propionohydroxamic acid, 3-(benzylamino)-, monohydrochloride; DTXSID60946374; BDBM50457058; 3-(Benzylamino)-N-hydroxypropanimidic acid
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|
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| Activity |
IC50 = 50000 nM
|
[9] | |||
| Compound Name |
N-(6-Methoxyquinolin-8-yl)-6-(sulfamoylamino)hexanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL515295; SCHEMBL5457540; BDBM50277292
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
6-Methylquinoline-8-thiol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4101230; 6-Methyl-8-mercaptochinolin; 8-Quinolinethiol, 6-methyl-; SCHEMBL18526845; BDBM50264491
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|
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| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
5-(4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)-N-hydroxyfuran-2-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630117; SCHEMBL8471544; BDBM50332490
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
N-[2-Amino-5-[4-(2-phenylethyl)phenyl]phenyl]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL402973; BDBM50374052
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
3-(3-Bromo-4-methoxyphenyl)-N-(2-methylsulfanylethyl)-2-oxopropanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2047672; BDBM50386464
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(2E)-3-(3-Bromo-4-hydroxyphenyl)-2-hydrazinylidene-N-(2-methylsulfanylethyl)propanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2047676; BDBM50386433
Click to Show/Hide
|
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| Activity |
IC50 = 50000 nM
|
[8] | |||
| Compound Name |
N-(2-Chlorophenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4104197; BDBM50235702
Click to Show/Hide
|
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| Activity |
Ki ~ 50000 nM
|
[13] | |||
| Compound Name |
3-Methylquinoline-8-thiol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4100994; 8-Quinolinethiol, 3-methyl-; 3-methyl-8-quinolinethiol; SCHEMBL3067414; BDBM50264503
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
3-[(4-Acetamidobenzoyl)amino]-4-amino-N-methylbenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL269944; BDBM50374055
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-[2-Amino-5-(4-phenoxyphenyl)phenyl]pyridine-3-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL402117; BDBM50374008
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
Azumamide D
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL257973; BDBM50377382
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
N-(2-Amino-5-fluorophenyl)pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL401586; BDBM50374026; AKOS006183255
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
Chembl4168767
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50361183
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|
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| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
N-(2-Hydroxy-5-phenylphenyl)-2-phenylacetamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL401750; BDBM50374015
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-[2-Amino-5-[4-(morpholine-4-carbonyl)phenyl]phenyl]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL257427; BDBM50374043
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(2-methylphenyl)octanediamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4080874; BDBM50235706
Click to Show/Hide
|
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| Activity |
Ki ~ 50000 nM
|
[13] | |||
| Compound Name |
N-[2-Amino-5-(4-benzoylphenyl)phenyl]pyridine-3-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL257949; BDBM50374053
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-(2-Aminophenyl)-5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)thiophene-2-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630112; SCHEMBL8470325; BDBM50332485
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
3-[(4-Acetamidobenzoyl)amino]-4-aminobenzoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL269945; BDBM50374009
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-[4-(Dimethylamino)phenyl]-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4066515; BDBM50235703
Click to Show/Hide
|
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| Activity |
Ki ~ 50000 nM
|
[13] | |||
| Compound Name |
4-Acetamido-N-(2-fluoro-5-phenylphenyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL271497; BDBM50374058
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-[2-Amino-5-(methylcarbamoyl)phenyl]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL271032; BDBM50374030
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-(3-Chlorophenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4093113; BDBM50235705
Click to Show/Hide
|
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| Activity |
Ki ~ 50000 nM
|
[13] | |||
| Compound Name |
4-[[2-Ethyl-4-oxo-3-(2-phenylethyl)quinazolin-8-yl]methyl]-N-hydroxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2425952; SCHEMBL15301999; BDBM50440045
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[16] | |||
| Compound Name |
2-[(3-Bromo-4-hydroxyphenyl)methyl]-N-[2-[2-[2-[(3-bromo-4-hydroxyphenyl)methyl]prop-2-enoylamino]ethyldisulfanyl]ethyl]prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2047682; BDBM50386473
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
3-[5-(Trifluoroacetyl)thiophen-2-yl]benzoic Acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL569193; 3-(5-(2,2,2-trifluoroacetyl)thiophen-2-yl)benzoic acid; 3-[5-(2,2,2-trifluoroacetyl)thiophen-2-yl]benzoic acid; SCHEMBL2224563; BDBM50300003
Click to Show/Hide
|
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| Activity |
EC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
4-[4-Amino-3-(pyridine-3-carbonylamino)phenyl]benzoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL269947; BDBM50374045
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
4-Amino-3-(pyridine-3-carbonylamino)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL408755; BDBM50374032
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-[2-Amino-5-[4-(4-phenylpiperazin-1-yl)phenyl]phenyl]pyridine-3-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL428600; BDBM50374051
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
3-[(4-Acetamidobenzoyl)amino]-4-amino-N-phenylbenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL273153; BDBM50374054
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2-(2,2-Dimethylpropanoyl)-N-hydroxy-1,3-dihydroisoindole-5-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431907; SCHEMBL1262950; BDBM50440909
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-1,3,4,5-tetrahydro-2-benzazepine-7-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431912; SCHEMBL1264164; BDBM50440908
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
N-(2-Aminophenyl)-5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630111; SCHEMBL8474331; BDBM50332484
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-(4-fluorophenyl)-N'-hydroxyoctanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4079958; BDBM50235708
Click to Show/Hide
|
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| Activity |
Ki ~ 50000 nM
|
[13] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(4-methoxyphenyl)octanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4095542; BDBM50235707
Click to Show/Hide
|
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| Activity |
Ki ~ 50000 nM
|
[13] | |||
| Compound Name |
N-[2-Amino-5-(trifluoromethyl)phenyl]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL402092; BDBM50374028
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-Hydroxy-2-[(1-methyl-1H-pyrrol-2-yl)carbonyl]isoindoline-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431906; SCHEMBL1263733; BDBM50440910; N-hydroxy-2-(1-methylpyrrole-2-carbonyl)-1,3-dihydroisoindole-5-carboxamide
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
2-(2,2-Dimethylpropanoyl)-N-hydroxy-3,4-dihydro-1H-isoquinoline-6-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431902; SCHEMBL1263305; BDBM50440911
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
N-(2-Amino-5-methylphenyl)pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL270818; BDBM50374029
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
Azumamide A
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL255714; BDBM50377385
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
Methyl 4-amino-3-(pyridine-3-carbonylamino)benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL272365; BDBM50374031
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(3-methylphenyl)octanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4098910; BDBM50235701
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[13] | |||
| Compound Name |
n-(4-Phenylthiazol-2-yl)-6-(sulfamoylamino)hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493347; SCHEMBL5326834; BDBM50257271; N-(4-phenyl-1,3-thiazol-2-yl)-6-(sulfamoylamino)hexanamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
(E)-N-Hydroxy-5-(2-hydroxy-3-methoxystyryl)furan-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL513589; BDBM50244920
Click to Show/Hide
|
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| Activity |
IC50 = 50140 nM
|
[19] | |||
| Compound Name |
4-Methylaminobenzohydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3415449; SCHEMBL18229691; BDBM50078753
Click to Show/Hide
|
||||
| Activity |
IC50 = 52300 nM
|
[20] | |||
| Compound Name |
4-[[2-[2-(Dimethylamino)ethyl]benzimidazol-1-yl]methyl]-N-hydroxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3952983; SCHEMBL12850061; BDBM218195; US9249087, 38
Click to Show/Hide
|
||||
| Activity |
IC50 = 52400 nM
|
[21] | |||
| Compound Name |
N-(2-Amino-5-azidophenyl)-4-(3-azidopropanoylamino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2057829; SCHEMBL16291285; BDBM50387972
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[22] | |||
| Compound Name |
(2R)-2-[[(2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-4,6-dimethyl-7-oxohepta-2,4-dienoyl]amino]-3-hydroxy-2-methylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2011674; JBIR-111; BDBM50379297
Click to Show/Hide
|
||||
| Activity |
IC50 = 57000 nM
|
[23] | |||
| Compound Name |
Chembl4204967
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50457065
Click to Show/Hide
|
||||
| Activity |
IC50 = 57000 nM
|
[9] | |||
| Compound Name |
4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[2-[3-(hydroxyamino)-3-oxopropoxy]ethyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3966165; BDBM50199114
Click to Show/Hide
|
||||
| Activity |
IC50 = 58100 nM
|
[24] | |||
| Compound Name |
3-[(2E,4E)-5-(3,4-Dimethoxyphenyl)penta-2,4-dienoyl]-7-methoxychromen-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3318732; BDBM50052830
Click to Show/Hide
|
||||
| Activity |
IC50 = 59000 nM
|
[25] | |||
| Compound Name |
(2E,4E)-5-[4-[3-(1-Adamantyl)-4-methoxyphenyl]phenyl]-N-hydroxypenta-2,4-dienamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3235787; BDBM50005732
Click to Show/Hide
|
||||
| Activity |
IC50 = 60100 nM
|
[26] | |||
| Compound Name |
N-Hydroxy-5-[1-[6-(pent-4-enoylamino)pyridin-3-yl]ethyl]-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2046619; BDBM50387314
Click to Show/Hide
|
||||
| Activity |
IC50 = 65710 nM
|
[27] | |||
| Compound Name |
N-Hydroxy-3-[[(E)-3-phenylprop-2-enoyl]amino]propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2088208; SCHEMBL12672509; BDBM50421331
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[28] | |||
| Compound Name |
Methyl (2S)-2-[[9-(hydroxyamino)-9-oxononanoyl]amino]-3-pyridin-2-ylpropanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2417786
Click to Show/Hide
|
||||
| Activity |
IC50 = 67300 nM
|
[5] | |||
| Compound Name |
6-[(3S,6S,9S,12R)-3,9-Bis(1H-indol-3-ylmethyl)-2,5,8,11-tetraoxo-1,4,7,10-tetrazabicyclo[10.3.0]pentadecan-6-yl]-N-hydroxyhexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1096986; BDBM50317650
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[29] | |||
| Compound Name |
2-[[(2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-4,6-dimethyl-7-oxohepta-2,4-dienoyl]amino]ethanesulfonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
JBIR-110; CHEMBL2011673; BDBM50379296
Click to Show/Hide
|
||||
| Activity |
IC50 = 74000 nM
|
[23] | |||
| Compound Name |
4-[[(3S)-1-(4-Chlorophenyl)-2-oxo-3-methylpyrrolidine-3-yl]amino]benzhydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3415629; BDBM50078748; J3.522.188C
Click to Show/Hide
|
||||
| Activity |
IC50 = 74100 nM
|
[20] | |||
| Compound Name |
Ethyl 4-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-3-oxobutanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800383; BDBM50348384; AKOS013207288
Click to Show/Hide
|
||||
| Activity |
IC50 = 77200 nM
|
[30] | |||
| Compound Name |
N-[3-(Hydroxyamino)-3-oxopropyl]-3-(4-methylphenyl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2088205; BDBM50421334
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[28] | |||
| Compound Name |
N-Hydroxy-2-pyrazin-2-yl-1,3-thiazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3771210; BDBM50148606
Click to Show/Hide
|
||||
| Activity |
IC50 = 82250 nM
|
[31] | |||
| Compound Name |
2-(4-Chlorophenacylthio)-4-hydroxy-6-methylpyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800375; 2-[2-(4-chlorophenyl)-2-oxoethylthio]-6-methyl-3-hydropyrimidin-4-one; BAS 00853818; MLS001143876; CTK6G9149; CCG-304; BDBM50348376; SBB085170; STL281529; STL330245; ZINC17750270; AKOS000565394; AKOS001021795; AKOS003625541; MCULE-8980888190; SMR000473315; ST50113505; AE-641/01210025; SR-01000637247-1; 1-(4-Chlorophenyl)-2-((4-hydroxy-6-methylpyrimidin-2-yl)thio)ethan-1-one; 1-(4-chlorophenyl)-2-[(4-hydroxy-6-methylpyrimidin-2-yl)thio]ethanone; 2-((2-(4-Chlorophenyl)-2-oxoethyl)thio)-6-methylpyrimidin-4(3H)-one; 2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-6-methyl-4(3H)-pyrimidinone; 2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-6-methylpyrimidin-4(1H)-one; 2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-6-methylpyrimidin-4(3H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 82300 nM
|
[30] | |||
| Compound Name |
Methyl (2R)-2-[[9-(hydroxyamino)-9-oxononanoyl]amino]-3-pyridin-2-ylpropanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2417785
Click to Show/Hide
|
||||
| Activity |
IC50 = 82600 nM
|
[5] | |||
| Compound Name |
2-Benzyl-N-hydroxy-1,3-thiazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770119; BDBM50148608
Click to Show/Hide
|
||||
| Activity |
IC50 = 83580 nM
|
[31] | |||
| Compound Name |
N-(2-(3-(2-Aminophenylamino)-3-oxopropylamino)-2-oxoethyl)-4-methylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL550573; BDBM50294536
Click to Show/Hide
|
||||
| Activity |
IC50 = 83900 nM
|
[32] | |||
| Compound Name |
N-Hydroxy-3-[[2-(4-methylphenoxy)acetyl]amino]propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2088204; BDBM50421335
Click to Show/Hide
|
||||
| Activity |
IC50 = 84000 nM
|
[28] | |||
| Compound Name |
2-Benzyl-N-hydroxy-N'-phenyloctanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL435160; BDBM50212245
Click to Show/Hide
|
||||
| Activity |
IC50 = 84000 nM
|
[33] | |||
| Compound Name |
N-[6-(2-Amino-4-bromoanilino)-6-oxohexyl]-4-methylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL1938025; CHEMBL3981124; BDBM207666; US9265734, R146
Click to Show/Hide
|
||||
| Activity |
IC50 = 84000 nM
|
[34] | |||
| Compound Name |
(S)-2-((S)-2-((S)-1-((S)-2-Amino-3-phenylpropanoyl)pyrrolidine-2-carboxamido)-8-(2-aminophenylamino)-8-oxooctanamido)-3-phenylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL554395; BDBM50294540
Click to Show/Hide
|
||||
| Activity |
IC50 = 84200 nM
|
[32] | |||
| Compound Name |
[4-(Azidomethyl)phenyl]methyl 8-[4-[(3-azido-5-methoxyphenyl)methoxy]anilino]-8-oxooctanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2170174; BDBM50397358
Click to Show/Hide
|
||||
| Activity |
IC50 = 86000 nM
|
[35] | |||
| Compound Name |
(2R)-2-[(1-Hydroxy-6-sulfanylidenepyridine-2-carbonyl)amino]-2-phenylacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3260858; BDBM50014161
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[36] | |||
| Compound Name |
2-Benzhydryl-N-hydroxy-1,3-oxazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770136; BDBM50148614
Click to Show/Hide
|
||||
| Activity |
IC50 = 93890 nM
|
[31] | |||
| Compound Name |
2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(6-phenylhexyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800385; BDBM50348387
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
2-{[2-(4-Tert-butylphenyl)-2-oxoethyl]sulfanyl}-6-methyl-3,4-dihydropyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800374; ZINC9143521; BDBM50348375; AKOS034466005; MCULE-3132766776; Z56923981
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-(2-Aminophenyl)-3-(5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-yl)acrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630113; SCHEMBL4077722; SCHEMBL4077728; BDBM50332486
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
N-[4-[2-(4-Methylpyrimidin-2-yl)sulfanylacetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800242; BDBM50348389
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
(E)-N-Hydroxy-3-[1-(5-hydroxypentyl)-2-(2-phenylethyl)benzimidazol-5-yl]prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM1662; SCHEMBL3372830; CHEMBL3648304; US8551988, 78
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
(1S,14S,17R,23S)-23-Propan-2-yl-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3310510; BDBM50048862
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[3-(sulfamoylamino)propyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3974665; BDBM50199124
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
N-(2-Aminophenyl)-3-(2-phenethyl-1-(pyridin-2-ylmethyl)-1H-benzo[d]imidazol-5-yl)acrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL489902; BDBM50247928
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
N-Hydroxy-4-[(3-methyl-2-oxo-1-phenylpyrrolidin-3-yl)amino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3415626; SCHEMBL11030300; BDBM50078693
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-[4-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800248; SCHEMBL17382802; BDBM50348395
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-Hydroxy-4-(2-oxo-1-phenylpyrrolidin-3-yl)oxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3415448; BDBM50078752
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
Chembl4225827
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50460799
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(R)-7-(Biphenyl-3-ylamino)-7-oxo-6-(thiazole-5-carbonylamino)heptylboronic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492174; BDBM50250151
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
N-Hydroxy-3-[1-(2-phenylethyl)triazol-4-yl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178344; NCC-32; BDBM50399674
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
Propan-2-Yl N-[(2s,4r)-1-Ethanoyl-2-Methyl-6-[4-(Methylaminomethyl)phenyl]-3,4-Dihydro-2h-Quinolin-4-Yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3220926; SCHEMBL11980283; Q27456822
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[42] | |||
| Compound Name |
(1R,14S,17R,23S)-23-Benzyl-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3310508; BDBM50048860
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
N-[4-[2-[(4-Methyl-6-oxo-1H-pyridin-2-yl)oxy]acetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800247; BDBM50348394
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[6-(sulfamoylamino)hexyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3903756; BDBM50199123
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
Schembl21996151
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3926959; BDBM50199122
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
Nutlin-3A
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Nutlin 3a; (-)-Nutlin-3; Nutlin-3a chiral; UNII-L7C92IOE65; nutlin 3; CHEMBL191334; L7C92IOE65; 548472-68-0 (4R5S, and 4S5R); Nutlin3a; C30H30Cl2N4O4; Nutlin (3a); Nutlin-3a (chiral); (4S,5R)-Nutlin-3; Nutlin-3, (-)-; cc-452; SCHEMBL1155752; HMS3649P17; Nutlin-3a, >=98% (HPLC); EX-A1359; 1960AH; 2603AH; BDBM50229787; MFCD14636430; s8059; ZINC16051336; AKOS027422740; BCP9001003; CS-0296; SB19406; NCGC00344347-05; AS-75148; HY-10029; SC-95163; A11501; W-5585; SR-01000946691; SR-01000946691-1; Q27166862; 675576-98-4 (4S5R); UNII-53IA0V845C component BDUHCSBCVGXTJM-WUFINQPMSA-N
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[43] | |||
| Compound Name |
2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(4-phenylbutyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800384; BDBM50348385
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
(1R,14S,17R,23S)-23-Propan-2-yl-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3310507; BDBM50048859
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
(1S,12R,15S,18R)-15-Propan-2-yl-24,25-dithia-3,14,17,31-tetrazatetracyclo[16.12.2.03,12.05,10]dotriaconta-5,7,9-triene-2,13,16,32-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3310511; BDBM50048863
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
1-((4-Hydroxy-6-methylpyrimidin-2-yl)thio)propan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800381; BDBM50348382; STL267143; AKOS008981021; AKOS016354209; MCULE-9373031239; 6-methyl-2-[(2-oxopropyl)sulfanyl]pyrimidin-4(3H)-one; 1-[(4-Oxo-6-methyl-3,4-dihydropyrimidine-2-yl)thio]-2-propanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-[4-[2-(3-Hydroxyphenyl)sulfanylacetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800245; BDBM50348392
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-[4-[1-Hydroxy-2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]ethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800249; BDBM50348396
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[3-(3-hydroxy-2-oxopyridin-1-yl)propyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3982650; BDBM50199120
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
(3S,6Z,9S,12R,16S)-6-Ethylidene-16-[(E)-4-methylsulfanylbut-1-enyl]-9-(methylsulfanylmethyl)-3,12-di(propan-2-yl)-1-oxa-4,7,10-triazacyclohexadecane-2,5,8,11,14-pentone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2093007
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[44] | |||
| Compound Name |
E,E-5-(4''-Methoxybiphenyl-4-yl)-penta-2,4-dienoic acid Nhydroxyamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL538364; BDBM50293369
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
2-[2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl]sulfanyl-4-methyl-1H-pyrimidin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800377; SCHEMBL17382809; BDBM50348378
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
(R)-6-(Benzenecarbonylamino)-7-(biphenyl-3-ylamino)-7-oxoheptylboronic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492140; BDBM50250098
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
2-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]-N-(2-phenylethyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000531589; CHEMBL1722433; SMR000136527; 2-[(4-methyl-6-oxo-1,6-dihydro-2-pyrimidinyl)thio]-N-(2-phenylethyl)acetamide; Oprea1_304490; cid_892234; BDBM96613; HMS2466G16; STK116346; ZINC18093765; AKOS000716785; AKOS001049225; MCULE-1856560484; SR-01000264561; SR-01000264561-1; Z56847664; 2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phenethyl-acetamide; 2-[(6-methyl-4-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(2-phenylethyl)acetamide; 2-[(6-methyl-4-oxo-1H-pyrimidin-2-yl)thio]-N-(2-phenylethyl)acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-Hydroxy-3-[1-(2-thiophen-3-ylethyl)triazol-4-yl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178343; NCC-142; BDBM50399673
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
N-Hydroxy-3-[2-(phenylsulfanylmethyl)-1,3-thiazol-4-yl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4105617; NCC-170; BDBM50252383
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
2-[2-(4-Hydroxyphenyl)-2-oxoethyl]sulfanyl-4-methyl-1H-pyrimidin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800376; BDBM50348377
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-{4-[2-(4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-acetyl]-phenyl}-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800244; Oprea1_373990; Oprea1_543124; ZINC841137; BDBM50348391; STK285981; AKOS001628005; MCULE-9514505423; N-(4-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}phenyl)acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
6-Methyl-2-phenacylsulfanyl-1H-pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800250; 2-((4-hydroxy-6-methylpyrimidin-2-yl)thio)-1-phenylethanone; 6-methyl-2-(2-oxo-2-phenylethylthio)-3-hydropyrimidin-4-one; NSC338484; CBKinase1_000908; CBKinase1_013308; Cambridge id 5509606; IFLab1_000456; CTK0H7748; DTXSID70319010; HMS1413E16; ZINC9446020; BDBM50348397; SBB085164; STK830457; STL281533; 6-methyl-2-[(2-oxo-2-phenylethyl)sulfanyl]-3,4-dihydropyrimidin-4-one; AKOS000565987; AKOS001012387; AKOS003626716; MCULE-4095585670; NSC-338484; IDI1_008675; ST50113123; 2-Benzoylmethylmercapto-4-methyl-6-oxypyrimidin; AB00087040-01; SR-01000416787; SR-01000416787-1; BRD-K22643941-001-01-6; Z56767694; F0176-0059; 6-methyl-2-(2-oxo-2-phenylethyl-thio)pyrimidin-4(3h)-one; 6-methyl-2-[(2-oxo-2-phenylethyl)thio]-4(1H)-pyrimidinone; 2-[(4-hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-phenylethanone; 6-METHYL-2-((2-OXO-2-PHENYLETHYL)THIO)-4(3H)-PYRIMIDINONE; 6-methyl-2-[(2-oxo-2-phenylethyl)sulfanyl]-4(3H)-pyrimidinone; 6-methyl-2-[(2-oxo-2-phenylethyl)sulfanyl]pyrimidin-4(3H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-Methyl-N-[4-[2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800251; BDBM50348372
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
(1R,14S,17R,23S)-23-Benzyl-4-oxa-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2158742; BDBM50394110
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
(E)-N-(2-Aminophenyl)-3-(3-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)phenyl)acrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630114; SCHEMBL4080581; SCHEMBL4080585; BDBM50332487
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
Chembl4282866
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50470498; ZINC38895935; AT-096/43397269; 4-[2-(1,3-benzothiazol-2-yl)vinyl]-N,N-diethylbenzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[47] | |||
| Compound Name |
2-(Tert-butylcarbonylmethylthio)-4-hydroxy-6-methylpyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800382; Maybridge1_007088; CTK6C4190; HMS561K04; BDBM50348383; SBB099296; ZINC13468269; AKOS008981059; CCG-244729; MCULE-6331991984; 1-(4-hydroxy-6-methylpyrimidin-2-ylthio)-3,3-dimethylbutan-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
Chembl4226814
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50460796
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
Hdac3-IN-T326
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3622375; N-(2-Aminophenyl)-5-(1-(3-nitrophenethyl)-1H-1,2,3-triazol-4-yl)thiophene-2-carboxamide; BDBM50121211; T-326; N-(2-aminophenyl)-5-[1-[2-(3-nitrophenyl)ethyl]triazol-4-yl]thiophene-2-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[48] | |||
| Compound Name |
2-[(4-Hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-(4-methoxyphenyl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1307946; SMR000104980; CBMicro_000564; Oprea1_387281; Oprea1_513871; MLS000109033; REGID_for_CID_722456; HMS2167C19; HMS3314O04; SMSF0007972; ZINC8632101; BDBM50348374; STK927199; STL281551; AKOS000566015; AKOS002232718; AKOS008969277; CB01814; MCULE-2661039450; BIM-0000433.P001; ST50112774; AB00097791-01; AB00097791-06; SR-01000417195; SR-01000417195-1; 2-[2-(4-methoxyphenyl)-2-oxoethylthio]-6-methyl-3-hydropyrimidin-4-one; 2-{[2-(4-methoxyphenyl)-2-oxoethyl]sulfanyl}-6-methylpyrimidin-4(3H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
(R)-7-(Biphenyl-3-ylamino)-7-oxo-6-(pyridine-3-carbonylamino)heptylboronic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL491926; BDBM50250100
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
S-7-Oxo-7-(4-phenylthiazol-2-ylamino)heptyl 2-methyl-3-phenylpropanethioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL384522; BDBM50203548; 2-Methyl-3-phenylpropanethioic acid S-[7-oxo-7-[(4-phenyl-2-thiazolyl)amino]heptyl] ester
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
Chembl4209492
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50457064
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
N-[4-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)oxy]acetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800246; BDBM50348393
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
6-[3-(4-Benzenesulfonylamino-benzoyl)-ureido]-hexanoic acid hydroxyamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1084019; BDBM50319218
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[50] | |||
| Compound Name |
Methyl 2-((4-hydroxy-6-methylpyrimidin-2-yl)thio)acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800380; methyl 2-(6-methyl-4-oxo-3-hydropyrimidin-2-ylthio)acetate; BDBM50348381; SBB062603; STK641838; STL281936; ZINC13739146; AKOS002262380; AKOS002308199; AKOS008981057; MCULE-6551097558; 2-Methoxycarbonylmethylenethio-6-methyluracil; ST50186106; methyl [(4-hydroxy-6-methylpyrimidin-2-yl)sulfanyl]acetate; methyl [(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetate; [(4-Oxo-3,4-dihydro-6-methylpyrimidine-2-yl)thio]acetic acid methyl ester; METHYL ((4-METHYL-6-OXO-1,6-DIHYDRO-2-PYRIMIDINYL)THIO)ACETATE; Methyl [(4-methyl-6-oxo-1,6-dihydro-2-pyrimidinyl)sulfanyl]acetate #
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-(2-Aminophenyl)-4-((naphthalen-2-ylmethylthio)methyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163806; BDBM50320751
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[51] | |||
| Compound Name |
N-Hydroxy-4-[methyl-(2-oxo-1-phenylpyrrolidin-3-yl)amino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3415447; BDBM50078751
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
(e)-n-(2-Aminophenyl)-3-(4-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)phenyl)acrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630115; SCHEMBL4079463; SCHEMBL4079470; BDBM50332488
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
1-(3,4-Dihydroxyphenyl)-2-[(4-hydroxy-6-methylpyrimidin-2-YL)thio]ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL209453; CHEMBRDG-BB 6606317; MLS001212148; SMR000518041; 1-(3,4-Dihydroxy-phenyl)-2-(4-hydroxy-6-methyl-pyrimidin-2-ylsulfanyl)-ethanone; 1-(3,4-Dihydroxyphenyl)-2-((4-hydroxy-6-methylpyrimidin-2-yl)thio)ethanone; Cambridge id 6606317; Oprea1_441814; cid_687937; SCHEMBL17382815; BDBM55151; CTK4I6835; DTXSID20350771; KUC104368N; BDBM50477568; MFCD02366437; STK770887; ZINC18163844; 2-[2-(3,4-dihydroxyphenyl)-2-oxoethyl]sulfanyl-6-methyl-1H-pyrimidin-4-one; AKOS000563316; AKOS001653377; AKOS008967906; KSC-10-146; MCULE-3270859217; W-9419; 2-[[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio]-6-methyl-1H-pyrimidin-4-one; 2-{[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio}-6-methylpyrimidin-4(3H)-one; 1-(3,4-dihydroxyphenyl)-2-(4-hydroxy-6-methyl-pyrimidin-2-yl)sulfanyl-ethanone; 1-(3,4-Dihydroxyphenyl)-2-[(4-hydroxy-6-methyl-2-pyrimidinyl)thio]ethanone; 2-[[2-(3,4-dihydroxyphenyl)-2-keto-ethyl]thio]-6-methyl-1H-pyrimidin-4-one; 2-{[2-(3,4-dihydroxyphenyl)-2-oxoethyl]sulfanyl}-6-methylpyrimidin-4(3H)-one; Ethanone, 1-(3,4-dihydroxyphenyl)-2-[(4-hydroxy-6-methyl-2-pyrimidinyl)thio]-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
(E)-3-[4-[3-(1-Adamantyl)-4-hydroxyphenyl]phenyl]-N-hydroxyprop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3235463; SCHEMBL3295457; SCHEMBL3295460; BDBM50005744; E-3-[3'-(1-adamantyl)-4'-hydroxy-biphenyl-4-yl]-N-hydroxy-acrylamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
6-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]-1,3-dihydroindol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800378; SCHEMBL17382803; BDBM50348379
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-[4-[2-(4-Methoxy-6-methylpyrimidin-2-yl)sulfanylacetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800243; BDBM50348390
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
(E)-N-(2-Aminophenyl)-3-[4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluorophenyl]prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3948452; BDBM50199119
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
6-Methyl-2-{[2-oxo-2-(thiophen-2-yl)ethyl]sulfanyl}-3,4-dihydropyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800379; ChemDiv3_001859; SCHEMBL13401534; HMS1478E11; BDBM50348380; ZINC18084678; AKOS001038722; AKOS008966863; CCG-107559; MCULE-5001803542; IDI1_020825; Z56864923
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-[4-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800373; BDBM50348373
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-(2-Aminophenyl)-4-((naphthalen-2-ylthio)ethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163553; BDBM50320750
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[51] | |||
| Compound Name |
4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[6-(3-hydroxy-2-oxopyridin-1-yl)hexyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3912767; BDBM50199112
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
(1R,14S,17R,23S)-23-Methyl-4-oxa-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3310509; BDBM50048861
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
N-Hydroxy-4-[(5-oxo-1-phenylpyrrolidin-3-yl)amino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3415450; SCHEMBL11029930; BDBM50078754
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
Chembl4206055
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50457049
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
2-Azidoethyl 8-[4-[(3-azido-5-methoxyphenyl)methoxy]anilino]-8-oxooctanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2170173; BDBM50397359
Click to Show/Hide
|
||||
| Activity |
IC50 = 111000 nM
|
[35] | |||
| Compound Name |
2-(4-Hydroxybenzylidene)-1-benzofuran-3(2H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NSC657003; CHEMBL199974; (Z)-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one; (2Z)-2-(4-hydroxybenzylidene)-1-benzofuran-3(2H)-one; SCHEMBL19462962; (2Z)-2-[(4-hydroxyphenyl)methylidene]-1-benzofuran-3-one; BDBM50036880; ZINC12341651; AKOS001694044; NSC-657003; AN-308/15495080; 2-[(Z)-4-Hydroxybenzylidene]benzofuran-3(2H)-one; (2Z)-2-[(4-hydroxyphenyl)methylene]benzofuran-3-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 129200 nM
|
[52] | |||
| Compound Name |
3-(Cyclohexylamino)-N-hydroxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3800299; BDBM50164657
Click to Show/Hide
|
||||
| Activity |
IC50 = 129900 nM
|
[53] | |||
| Compound Name |
Chembl4173739
Click to Show/Hide
|
Investigative | Compound Info | ||
| Activity |
IC50 ~ 160000 nM
|
[54] | |||
| Compound Name |
2-Hexyl-N-hydroxy-N'-phenyloctanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3982264; BDBM50212243
Click to Show/Hide
|
||||
| Activity |
IC50 = 180000 nM
|
[33] | |||
| Compound Name |
N-(2-Aminophenyl)-6-((2S,8S)-8-(3-guanidinopropyl)-3,6,9,12-tetraoxo-1,4,7,10-tetraazacyclododecan-2-yl)hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL559576; BDBM50294533
Click to Show/Hide
|
||||
| Activity |
IC50 = 191000 nM
|
[32] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 12 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Acetohydroxamic Acid
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
AHA; Acethydroxamsaeure; Acethydroxamsaure; Acetohydroxamate; HAE; Lithostat; Acethydroxamic acid; Acethydroxamsaeure [German]; Acetohydroximic acid; Acetyl hydroxyamino; Acetylhydroxamic acid; Acide acetohydroxamique; Acide acetohydroxamique [French]; Acido acetohidroxamico; Acido acetohidroxamico [Spanish]; Acidum acetohydroxamicum; Acidum acetohydroxamicum [Latin]; Cetohyroxamic acid; Methylhydroxamic acid; SJX HLdmMAH; AHA (TN); Acetic acid, oxime; Acetohydroxamic acid [USAN:INN]; Lithostat (TN); N-Acetyl hydroxyacetamide; N-Acetylhydroxylamine; N-Hydroxyacetamide; N-hydroxyacetimidic acid; N-hydroxyethanimidic acid; S14-0751; Acetohydroxamic acid (USP/INN); Acetamide, N-hydroxy-(9CI)
Click to Show/Hide
|
||||
| Activity |
IC50 = 625000 nM
|
[55] | |||
| Compound Name |
Tubacin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Tubacin; 537049-40-4; AC1O7Y2P; CHEMBL356769; 1350555-93-9; N1-(4-((2R,4R,6S)-4-(((4,5-Diphenyloxazol-2-yl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxyoctanediamide; Tubacin (BML-GR362); Octanediamide, N1-(4-((2R,4R,6S)-4-(((4,5-diphenyl-2-oxazolyl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxy-, rel-; N-[4-[(2R,4R,6S)-4-[[(4,5-Diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N'-hydroxyoctanediamide; SCHEMBL4741166
Click to Show/Hide
|
||||
| Activity |
EC50 = 217000 nM
|
[56] | |||
| Compound Name |
5-Methylquinoline-8-thiol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
8-Quinolinethiol, 5-methyl-; CHEMBL4084782; 5-methyl-8-quinolinethiol; SCHEMBL13977568; CTK1H9946; DTXSID70500764; BDBM50264484
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[11] | |||
| Compound Name |
4-Methylquinoline-8-thiol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
8-Quinolinethiol, 4-methyl-; CHEMBL4063134; 4-methyl-8-quinolinethiol; SCHEMBL15703126; CTK0B7293; DTXSID80492580; BDBM50264490
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[11] | |||
| Compound Name |
8-Mercaptoquinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
quinoline-8-thiol; 8-Quinolinethiol; SQT-8; 8-thioquinoline; [S]c1cccc2cccnc12; 8-Mercaptoquinoline (8TQ); NCIOpen2_001790; SCHEMBL536578; CHEMBL4076575; DTXSID70197678; BDBM224013; HMS1788G22; ZINC389710; NSC48888; NSC-48888; AKOS022191814; AKOS024342879; MCULE-9204136169; DB-070965; FT-0735097; MLS-0472512.0001; 8-Quinolinethiol;Quinoline-8-thiol;8-Thioquinoline; F9994-0398
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[11] | |||
| Compound Name |
3-[[(E)-3-[4-(Dimethylamino)phenyl]prop-2-enoyl]amino]-N-hydroxypropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2088203; BDBM50421336
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| Activity |
IC50 > 250000 nM
|
[28] | |||
| Compound Name |
(2R)-2-[(1-Hydroxy-6-sulfanylidenepyridine-2-carbonyl)amino]propanoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3260857; BDBM50014160
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| Activity |
IC50 = 270000 nM
|
[36] | |||
| Compound Name |
(2S)-2-Hexyl-N-hydroxy-N'-phenyloctanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3891027; BDBM50212244
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| Activity |
IC50 = 330000 nM
|
[33] | |||
| Compound Name |
2-((S)-2-(2-((S)-2-Amino-3-phenylpropanamido)acetamido)-8-(2-aminophenylamino)-8-oxooctanamido)acetic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL561909; BDBM50294535
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||||
| Activity |
IC50 = 532000 nM
|
[32] | |||
| Compound Name |
N-Hydroxy-2-propylpentanamide
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Investigative | Compound Info | ||
| Synonyms |
Valproic acid hydroxamate; Valpropylhydroxamic Acid; CHEMBL186311; 2-Propylpentanehydroximic acid; SCHEMBL15310210; DTXSID50147530; Pentanamide, N-hydroxy-2-propyl-; VAHA, >=98% (HPLC); ZINC5298743; 2-Propyl-pentanoic acid hydroxyamide; BDBM50336884; AKOS017536923; BCB03_000831; J-001544; BRD-K96146874-001-01-2; Q27216290
Click to Show/Hide
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| Activity |
IC50 = 560000 nM
|
[57] | |||
| Compound Name |
Bavarostat
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4165724; 4-(((((3r,5r,7r)-adamantan-1-yl)methyl)(methyl)amino)methyl)-3-fluoro-N-hydroxybenzamide; SCHEMBL20535390; GTPL11119; BDBM50369345; compound 4 [PMID: 30118224]
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| Activity |
IC50 > 1000000 nM
|
[58] | |||
| Compound Name |
3-(4-Chlorophenyl)-1-phenylpyrazolo[3,4-d]pyrimidin-4-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2408783; SCHEMBL13019674; BDBM50005017
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| Activity |
Ki > 12500000 nM
|
[59] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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