Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
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| Target ID | T70532 | Target Info | |||
| Target Name | NCK adaptor protein 1 (NCK1) | ||||
| Synonyms |
SH2/SH3 adaptor protein NCKalpha; SH2/SH3 adaptor protein NCK-alpha; Nck1; Nck-1; NCK; Cytoplasmic protein NCK1
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| Target Type | Clinical trial Target | ||||
| Gene Name | NCK1 | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
6-Methylquinolin-2-amine
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Investigative | Compound Info | ||
| Synonyms |
2-Quinolinamine, 6-methyl-; 6-Methyl-2-quinazolinamine; CHEMBL361660; 2-AMINO-6-METHYLQUINOLINE; 6-Methyl-quinolin-2-ylamine; SCHEMBL7048523; 6-METHYL-2-QUINOLINAMINE; DTXSID30431808; BDBM50154583; MFCD08235109; ZINC13584275; AKOS013465536; AB43746; AC-14800; AM806345; AS-54795
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| Activity |
EC50 = 90000 nM
|
[1] | |||
| Compound Name |
2-Aminoquinoline
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Investigative | Compound Info | ||
| Synonyms |
quinolin-2-amine; 2-Quinolinamine; Aminoquinoline; Quinolinamine; Quinoline, 2-amino-; quinolin-2-ylamine; 2-amino-quinoline; Fragment 19; UNII-GR9M8HW75Z; GR9M8HW75Z; CHEMBL61236; 2-quinolylamine; CCRIS 1677; EINECS 209-458-8; NSC 57739; NSC 58387; BRN 0113163; quinolimine; amino-quinoline; a-Aminoquinoline; 2-Quinolinylamine; 2-?Quinolinamine; quinoline-2-amine; 2-Aminoquinoline 1; PubChem5818; 2-Quinolinamine, 9CI; 2-Aminoquinoline, 97%; ACMC-1AH5U; 2-1H-QUINOLINIMINE; SCHEMBL38775; 5-22-10-00220 (Beilstein Handbook Reference); KSC223A9P; 2-imino-1,2-dihydroquinoline; SCHEMBL1146984; DTXSID2060381; BDBM14322; CTK1C3097; CTK4C1715; KS-00000FQW; HMS1719H05; ACT03947; BCP30417; NSC57739; NSC58387; ANW-32862; BBL100884; MFCD00038079; NSC-57739; NSC-58387; SBB051994; STL554678; ZINC19074717; AKOS000279069; CS-W007524; MCULE-9057285409; PS-4207; VQ10090; 2-Aminoquinoline pound>>2-Quinolinamine; NCGC00188269-01; AC-13271; AK-26798; BR-26798; SC-05494; DB-005975; fragment 2 (J. med. chem.,50,1116); A0417; AM20061864; FT-0632430; ST50409632; EN300-10204; S-1912; 22860-EP2286812A1; 22860-EP2295421A1; 22860-EP2308848A1; 22860-EP2315502A1; 22860-EP2371810A1; 22860-EP2371812A1; 580A223; A831703; AC-907/25014242; Q209310; J-400243; Z56347237
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| Activity |
EC50 = 150000 nM
|
[1] | |||
| Non Binders of This Target (in total, 2 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
2-Quinolinamine, 6-(1,3-dioxolan-2-yl)-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL366327; BDBM50154587; 6-(1,3-Dioxolane-2-yl)quinoline-2-amine; 6-[1,3]Dioxolan-2-yl-quinolin-2-ylamine
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| Activity |
EC50 = 300000 nM
|
[1] | |||
| Compound Name |
6-(1,3-Dioxane-2-yl)quinoline-2-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL426622; BDBM50154582; ZINC13584281; 6-[1,3]Dioxan-2-yl-quinolin-2-ylamine
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| Activity |
EC50 > 500000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Identification and specificity studies of small-molecule ligands for SH3 protein domains. J Med Chem. 2004 Oct 21;47(22):5405-17. | ||||
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