Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T70654 | Target Info | |||
| Target Name | Glutathione peroxidase (GPX1) | ||||
| Synonyms |
GSHPx-1; GPX1; Cellular glutathione peroxidase
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| Target Type | Literature-reported Target | ||||
| Gene Name | GPX1 | ||||
| Biochemical Class | Peroxidases | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 1 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(E)-N'-(4-Hydroxybenzylidene)-2-(2-methyl-1H-imidazol-1-yl)acetohydrazide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2165394; SCHEMBL15202985; BDBM50395834; AKOS024609254; SR-01000014564; SR-01000014564-1; F1725-0068
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| Activity |
IC50 = 169000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Identification of a glutathione peroxidase inhibitor that reverses resistance to anticancer drugs in human B-cell lymphoma cell lines. Bioorg Med Chem Lett. 2012 Nov 1;22(21):6712-5. | ||||
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